Cortical myoclonus in levodopa‐responsive parkinsonism
Identifieur interne : 005037 ( Main/Exploration ); précédent : 005036; suivant : 005038Cortical myoclonus in levodopa‐responsive parkinsonism
Auteurs : John N. Caviness [États-Unis] ; Charles H. Adler [États-Unis] ; Stephanie Newman [États-Unis] ; Richard J. Caselli [États-Unis] ; Manfred D. Muenter [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1998-05.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (administration & dosage), Brain Mapping, Case study, Cerebral Cortex (drug effects), Cerebral Cortex (physiopathology), Cerebral cortex, Cortex, Electroencephalography, Electroencephalography (drug effects), Electromyography, Electromyography (drug effects), Electrophysiology, Exploration, Follow-Up Studies, Human, Humans, Levodopa (administration & dosage), Male, Myoclonus, Myoclonus (drug therapy), Myoclonus (physiopathology), Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Parkinsonism.
- MESH :
- chemical , administration & dosage : Antiparkinson Agents, Levodopa.
- drug effects : Cerebral Cortex, Electroencephalography, Electromyography.
- drug therapy : Myoclonus, Parkinson Disease.
- physiopathology : Cerebral Cortex, Myoclonus, Parkinson Disease.
- Aged, Brain Mapping, Follow-Up Studies, Humans, Male.
Abstract
We observed myoclonic movements of the fingers and wrists in two patients with a levodopa‐responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (< 50 ms) myoclonic electromyographic discharges showed a time‐locked relationship to a focal premovement electroencephalographic potential. Somatosensoryevoked potentials were not enlarged and long‐latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.
Url:
DOI: 10.1002/mds.870130327
Affiliations:
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These patients were studied with electrophysiological techniques. Brief (< 50 ms) myoclonic electromyographic discharges showed a time‐locked relationship to a focal premovement electroencephalographic potential. Somatosensoryevoked potentials were not enlarged and long‐latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Arizona</li></region></list><tree><country name="États-Unis"><region name="Arizona"><name sortKey="Caviness, John N" sort="Caviness, John N" uniqKey="Caviness J" first="John N." last="Caviness">John N. Caviness</name></region><name sortKey="Adler, Charles H" sort="Adler, Charles H" uniqKey="Adler C" first="Charles H." last="Adler">Charles H. Adler</name><name sortKey="Caselli, Richard J" sort="Caselli, Richard J" uniqKey="Caselli R" first="Richard J." last="Caselli">Richard J. Caselli</name><name sortKey="Muenter, Manfred D" sort="Muenter, Manfred D" uniqKey="Muenter M" first="Manfred D." last="Muenter">Manfred D. Muenter</name><name sortKey="Newman, Stephanie" sort="Newman, Stephanie" uniqKey="Newman S" first="Stephanie" last="Newman">Stephanie Newman</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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