Cortical myoclonus in levodopa‐responsive parkinsonism
Identifieur interne : 003772 ( Istex/Checkpoint ); précédent : 003771; suivant : 003773Cortical myoclonus in levodopa‐responsive parkinsonism
Auteurs : John N. Caviness [États-Unis] ; Charles H. Adler [États-Unis] ; Stephanie Newman [États-Unis] ; Richard J. Caselli [États-Unis] ; Manfred D. Muenter [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1998-05.
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Abstract
We observed myoclonic movements of the fingers and wrists in two patients with a levodopa‐responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (< 50 ms) myoclonic electromyographic discharges showed a time‐locked relationship to a focal premovement electroencephalographic potential. Somatosensoryevoked potentials were not enlarged and long‐latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.
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DOI: 10.1002/mds.870130327
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1998-05">1998-05</date><biblScope unit="vol">13</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="540">540</biblScope><biblScope unit="page" to="544">544</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">D06F7283C58F171A52AAEF4618E141466A448B8B</idno><idno type="DOI">10.1002/mds.870130327</idno><idno type="ArticleID">MDS870130327</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cortex</term><term>Electrophysiology</term><term>Myoclonus</term><term>Parkinson's disease</term><term>Parkinsonism</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We observed myoclonic movements of the fingers and wrists in two patients with a levodopa‐responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (< 50 ms) myoclonic electromyographic discharges showed a time‐locked relationship to a focal premovement electroencephalographic potential. Somatosensoryevoked potentials were not enlarged and long‐latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Arizona</li></region></list><tree><country name="États-Unis"><region name="Arizona"><name sortKey="Caviness, John N" sort="Caviness, John N" uniqKey="Caviness J" first="John N." last="Caviness">John N. Caviness</name></region><name sortKey="Adler, Charles H" sort="Adler, Charles H" uniqKey="Adler C" first="Charles H." last="Adler">Charles H. 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