Cortical myoclonus in levodopa-responsive parkinsonism.
Identifieur interne : 004F72 ( Ncbi/Merge ); précédent : 004F71; suivant : 004F73Cortical myoclonus in levodopa-responsive parkinsonism.
Auteurs : J N Caviness [États-Unis] ; C H Adler ; S. Newman ; R J Caselli ; M D MuenterSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1998.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (administration & dosage), Brain Mapping, Cerebral Cortex (drug effects), Cerebral Cortex (physiopathology), Electroencephalography (drug effects), Electromyography (drug effects), Follow-Up Studies, Humans, Levodopa (administration & dosage), Male, Myoclonus (drug therapy), Myoclonus (physiopathology), Parkinson Disease (drug therapy), Parkinson Disease (physiopathology).
- MESH :
- chemical , administration & dosage : Antiparkinson Agents, Levodopa.
- drug effects : Cerebral Cortex, Electroencephalography, Electromyography.
- drug therapy : Myoclonus, Parkinson Disease.
- physiopathology : Cerebral Cortex, Myoclonus, Parkinson Disease.
- Aged, Brain Mapping, Follow-Up Studies, Humans, Male.
Abstract
We observed myoclonic movements of the fingers and wrists in two patients with a levodopa-responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (<50 ms) myoclonic electromyographic discharges showed a time-locked relationship to a focal premovement electroencephalographic potential. Somatosensory-evoked potentials were not enlarged and long-latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.
DOI: 10.1002/mds.870130327
PubMed: 9613750
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pubmed:9613750Le document en format XML
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Newman</name></author><author><name sortKey="Caselli, R J" sort="Caselli, R J" uniqKey="Caselli R" first="R J" last="Caselli">R J Caselli</name></author><author><name sortKey="Muenter, M D" sort="Muenter, M D" uniqKey="Muenter M" first="M D" last="Muenter">M D Muenter</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1998" type="published">1998</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (administration & dosage)</term><term>Brain Mapping</term><term>Cerebral Cortex (drug effects)</term><term>Cerebral Cortex (physiopathology)</term><term>Electroencephalography (drug effects)</term><term>Electromyography (drug effects)</term><term>Follow-Up Studies</term><term>Humans</term><term>Levodopa (administration & dosage)</term><term>Male</term><term>Myoclonus (drug therapy)</term><term>Myoclonus (physiopathology)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (physiopathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiparkinson Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cerebral Cortex</term><term>Electroencephalography</term><term>Electromyography</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Myoclonus</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cerebral Cortex</term><term>Myoclonus</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Brain Mapping</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We observed myoclonic movements of the fingers and wrists in two patients with a levodopa-responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (<50 ms) myoclonic electromyographic discharges showed a time-locked relationship to a focal premovement electroencephalographic potential. Somatosensory-evoked potentials were not enlarged and long-latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. These results provide evidence for a cortical origin of the myoclonus seen in these patients.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">9613750</PMID><DateCreated><Year>1998</Year><Month>08</Month><Day>10</Day></DateCreated><DateCompleted><Year>1998</Year><Month>08</Month><Day>10</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>13</Volume><Issue>3</Issue><PubDate><Year>1998</Year><Month>May</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Cortical myoclonus in levodopa-responsive parkinsonism.</ArticleTitle><Pagination><MedlinePgn>540-4</MedlinePgn></Pagination><Abstract><AbstractText>We observed myoclonic movements of the fingers and wrists in two patients with a levodopa-responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (<50 ms) myoclonic electromyographic discharges showed a time-locked relationship to a focal premovement electroencephalographic potential. Somatosensory-evoked potentials were not enlarged and long-latency reflexes were not grossly exaggerated. This pattern of electrophysiological findings can be distinguished from those previously found in other parkinsonian syndromes. 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Newman</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Caviness, J N" sort="Caviness, J N" uniqKey="Caviness J" first="J N" last="Caviness">J N Caviness</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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