Acute ataxia, Graves' disease, and stiff person syndrome
Identifieur interne : 003034 ( Main/Exploration ); précédent : 003033; suivant : 003035Acute ataxia, Graves' disease, and stiff person syndrome
Auteurs : Su-Ynn Chia [Singapour] ; Richard Chua [Singapour] ; Yew-Long Lo [Singapour] ; Meng-Cheong Wong [Singapour] ; Ling-Ling Chan [Singapour] ; Eng-King Tan [Singapour]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Antithyroid Agents (administration & dosage), Ataxia, Ataxia (diagnosis), Ataxia (immunology), Ataxia (therapy), Autoantibodies (blood), Carbimazole (administration & dosage), Combined Modality Therapy, Comorbidity, Diagnosis, Differential, Electromyography, Female, Glutamate Decarboxylase (immunology), Graves Disease (diagnosis), Graves Disease (immunology), Graves Disease (therapy), Graves disease, Graves' disease, Humans, Immunization, Passive, Immunosuppression, Middle Aged, Nervous system diseases, Neurologic Examination, Plasmapheresis, Stiff man syndrome, Stiff-Person Syndrome (diagnosis), Stiff-Person Syndrome (immunology), Stiff-Person Syndrome (therapy), Stroke (diagnosis), Thyrotoxicosis (diagnosis), Thyrotoxicosis (immunology), Thyrotoxicosis (therapy), ataxia, stiff person syndrome.
- MESH :
- chemical , administration & dosage : Antithyroid Agents, Carbimazole.
- chemical , blood : Autoantibodies.
- diagnosis : Ataxia, Graves Disease, Stiff-Person Syndrome, Stroke, Thyrotoxicosis.
- immunology : Ataxia, Glutamate Decarboxylase, Graves Disease, Stiff-Person Syndrome, Thyrotoxicosis.
- therapy : Ataxia, Graves Disease, Stiff-Person Syndrome, Thyrotoxicosis.
- Combined Modality Therapy, Comorbidity, Diagnosis, Differential, Electromyography, Female, Humans, Immunization, Passive, Immunosuppression, Middle Aged, Neurologic Examination, Plasmapheresis.
Abstract
Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21703
Affiliations:
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Le document en format XML
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<term>Ataxia</term>
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<term>Ataxia (immunology)</term>
<term>Ataxia (therapy)</term>
<term>Autoantibodies (blood)</term>
<term>Carbimazole (administration & dosage)</term>
<term>Combined Modality Therapy</term>
<term>Comorbidity</term>
<term>Diagnosis, Differential</term>
<term>Electromyography</term>
<term>Female</term>
<term>Glutamate Decarboxylase (immunology)</term>
<term>Graves Disease (diagnosis)</term>
<term>Graves Disease (immunology)</term>
<term>Graves Disease (therapy)</term>
<term>Graves disease</term>
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<term>Humans</term>
<term>Immunization, Passive</term>
<term>Immunosuppression</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Neurologic Examination</term>
<term>Plasmapheresis</term>
<term>Stiff man syndrome</term>
<term>Stiff-Person Syndrome (diagnosis)</term>
<term>Stiff-Person Syndrome (immunology)</term>
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<term>Stroke (diagnosis)</term>
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<term>Stiff-Person Syndrome</term>
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<term>Graves Disease</term>
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<term>Diagnosis, Differential</term>
<term>Electromyography</term>
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<term>Humans</term>
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<front><div type="abstract" xml:lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</div>
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<name sortKey="Chia, Su Nn" sort="Chia, Su Nn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
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