Movement Disorders (revue)

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Acute ataxia, graves' disease, and stiff person syndrome

Identifieur interne : 004398 ( Main/Merge ); précédent : 004397; suivant : 004399

Acute ataxia, graves' disease, and stiff person syndrome

Auteurs : Su-Ynn Chia [Singapour] ; Richard Chua [Singapour] ; Yew-Long Lo [Singapour] ; Meng-Cheong Wong [Singapour] ; Ling-Ling Chan [Singapour] ; Eng-King Tan [Singapour]

Source :

RBID : Pascal:08-0015802

Descripteurs français

English descriptors

Abstract

Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years.

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Pascal:08-0015802

Le document en format XML

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<name sortKey="Chan, Ling Ling" sort="Chan, Ling Ling" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name>
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<title level="j" type="main">Movement disorders</title>
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<term>Pathologie du système nerveux</term>
<term>Ataxie</term>
<term>Maladie de Basedow</term>
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<front>
<div type="abstract" xml:lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years.</div>
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<name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
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<name sortKey="Chan, Ling Ling" sort="Chan, Ling Ling" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name>
<name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
<name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name>
<name sortKey="Lo, Yew Long" sort="Lo, Yew Long" uniqKey="Lo Y" first="Yew-Long" last="Lo">Yew-Long Lo</name>
<name sortKey="Tan, Eng King" sort="Tan, Eng King" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name>
<name sortKey="Wong, Meng Cheong" sort="Wong, Meng Cheong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name>
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   |wiki=    Wicri/Santé
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   |étape=   Merge
   |type=    RBID
   |clé=     Pascal:08-0015802
   |texte=   Acute ataxia, graves' disease, and stiff person syndrome
}}

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