Acute ataxia, graves' disease, and stiff person syndrome
Identifieur interne : 004398 ( Main/Merge ); précédent : 004397; suivant : 004399Acute ataxia, graves' disease, and stiff person syndrome
Auteurs : Su-Ynn Chia [Singapour] ; Richard Chua [Singapour] ; Yew-Long Lo [Singapour] ; Meng-Cheong Wong [Singapour] ; Ling-Ling Chan [Singapour] ; Eng-King Tan [Singapour]Source :
- Movement disorders [ 0885-3185 ] ; 2007.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years.
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Pascal:08-0015802Le document en format XML
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<author><name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
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<author><name sortKey="Chan, Ling Ling" sort="Chan, Ling Ling" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name>
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<author><name sortKey="Tan, Eng King" sort="Tan, Eng King" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Acute ataxia, graves' disease, and stiff person syndrome</title>
<author><name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
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<sZ>3 aut.</sZ>
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<country>Singapour</country>
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<s3>SGP</s3>
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<author><name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name>
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<s3>SGP</s3>
<sZ>1 aut.</sZ>
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<country>Singapour</country>
<wicri:noRegion>Department of Neurology, National Neuroscience Institute, Singapore General Hospital</wicri:noRegion>
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<author><name sortKey="Wong, Meng Cheong" sort="Wong, Meng Cheong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name>
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<author><name sortKey="Chan, Ling Ling" sort="Chan, Ling Ling" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name>
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<s3>SGP</s3>
<sZ>5 aut.</sZ>
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<author><name sortKey="Tan, Eng King" sort="Tan, Eng King" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name>
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<s3>SGP</s3>
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<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
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<seriesStmt><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ataxia</term>
<term>Graves disease</term>
<term>Nervous system diseases</term>
<term>Stiff man syndrome</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Pathologie du système nerveux</term>
<term>Ataxie</term>
<term>Maladie de Basedow</term>
<term>Syndrome de l'homme raide</term>
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<front><div type="abstract" xml:lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years.</div>
</front>
</TEI>
<affiliations><list><country><li>Singapour</li>
</country>
</list>
<tree><country name="Singapour"><noRegion><name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
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<name sortKey="Chan, Ling Ling" sort="Chan, Ling Ling" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name>
<name sortKey="Chia, Su Ynn" sort="Chia, Su Ynn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name>
<name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name>
<name sortKey="Lo, Yew Long" sort="Lo, Yew Long" uniqKey="Lo Y" first="Yew-Long" last="Lo">Yew-Long Lo</name>
<name sortKey="Tan, Eng King" sort="Tan, Eng King" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name>
<name sortKey="Wong, Meng Cheong" sort="Wong, Meng Cheong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name>
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