Acute ataxia, Graves' disease, and stiff person syndrome
Identifieur interne : 003628 ( Istex/Corpus ); précédent : 003627; suivant : 003629Acute ataxia, Graves' disease, and stiff person syndrome
Auteurs : Su-Ynn Chia ; Richard Chua ; Yew-Long Lo ; Meng-Cheong Wong ; Ling-Ling Chan ; Eng-King TanSource :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
English descriptors
- KwdEn :
Abstract
Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21703
Links to Exploration step
ISTEX:3070736F0F60F59E6E6CD41354614296883642EFLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute ataxia, Graves' disease, and stiff person syndrome</title><author><name sortKey="Chia, Su Nn" sort="Chia, Su Nn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Endocrinology, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Lo, Yew Ong" sort="Lo, Yew Ong" uniqKey="Lo Y" first="Yew-Long" last="Lo">Yew-Long Lo</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Wong, Meng Heong" sort="Wong, Meng Heong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Chan, Ling Ing" sort="Chan, Ling Ing" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name><affiliation><mods:affiliation>Department of Radiology, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Tan, Eng Ing" sort="Tan, Eng Ing" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3070736F0F60F59E6E6CD41354614296883642EF</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21703</idno><idno type="url">https://api.istex.fr/document/3070736F0F60F59E6E6CD41354614296883642EF/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003628</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Acute ataxia, Graves' disease, and stiff person syndrome</title><author><name sortKey="Chia, Su Nn" sort="Chia, Su Nn" uniqKey="Chia S" first="Su-Ynn" last="Chia">Su-Ynn Chia</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Endocrinology, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Chua, Richard" sort="Chua, Richard" uniqKey="Chua R" first="Richard" last="Chua">Richard Chua</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Lo, Yew Ong" sort="Lo, Yew Ong" uniqKey="Lo Y" first="Yew-Long" last="Lo">Yew-Long Lo</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Wong, Meng Heong" sort="Wong, Meng Heong" uniqKey="Wong M" first="Meng-Cheong" last="Wong">Meng-Cheong Wong</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Chan, Ling Ing" sort="Chan, Ling Ing" uniqKey="Chan L" first="Ling-Ling" last="Chan">Ling-Ling Chan</name><affiliation><mods:affiliation>Department of Radiology, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Tan, Eng Ing" sort="Tan, Eng Ing" uniqKey="Tan E" first="Eng-King" last="Tan">Eng-King Tan</name><affiliation><mods:affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-10-15">2007-10-15</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">13</biblScope><biblScope unit="page" from="1969">1969</biblScope><biblScope unit="page" to="1971">1971</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">3070736F0F60F59E6E6CD41354614296883642EF</idno><idno type="DOI">10.1002/mds.21703</idno><idno type="ArticleID">MDS21703</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Graves' disease</term><term>ataxia</term><term>stiff person syndrome</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Su‐Ynn Chia MD</name><affiliations><json:string>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</json:string><json:string>Department of Endocrinology, Singapore General Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Richard Chua MD</name><affiliations><json:string>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Yew‐Long Lo MD</name><affiliations><json:string>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Meng‐Cheong Wong MD</name><affiliations><json:string>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Ling‐Ling Chan MD</name><affiliations><json:string>Department of Radiology, Singapore General Hospital, Singapore</json:string></affiliations></json:item><json:item><name>Eng‐King Tan MD</name><affiliations><json:string>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Graves' disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>stiff person syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ataxia</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</abstract><qualityIndicators><score>2.992</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>626</abstractCharCount><pdfWordCount>1960</pdfWordCount><pdfCharCount>13267</pdfCharCount><pdfPageCount>3</pdfPageCount><abstractWordCount>86</abstractWordCount></qualityIndicators><title>Acute ataxia, Graves' disease, and stiff person syndrome</title><genre><json:string>Serial article</json:string></genre><host><volume>22</volume><pages><total>3</total><last>1971</last><first>1969</first></pages><issn><json:string>0885-3185</json:string></issn><issue>13</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2007</publicationDate><copyrightDate>2007</copyrightDate><doi><json:string>10.1002/mds.21703</json:string></doi><id>3070736F0F60F59E6E6CD41354614296883642EF</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/3070736F0F60F59E6E6CD41354614296883642EF/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/3070736F0F60F59E6E6CD41354614296883642EF/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3070736F0F60F59E6E6CD41354614296883642EF/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Acute ataxia, Graves' disease, and stiff person syndrome</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2007</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Acute ataxia, Graves' disease, and stiff person syndrome</title><author><persName><forename type="first">Su‐Ynn</forename><surname>Chia</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><affiliation>Department of Endocrinology, Singapore General Hospital, Singapore</affiliation></author><author><persName><forename type="first">Richard</forename><surname>Chua</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation></author><author><persName><forename type="first">Yew‐Long</forename><surname>Lo</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation></author><author><persName><forename type="first">Meng‐Cheong</forename><surname>Wong</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation></author><author><persName><forename type="first">Ling‐Ling</forename><surname>Chan</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Radiology, Singapore General Hospital, Singapore</affiliation></author><author><persName><forename type="first">Eng‐King</forename><surname>Tan</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore</p></note><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-10-15"></date><biblScope unit="vol">22</biblScope><biblScope unit="issue">13</biblScope><biblScope unit="page" from="1969">1969</biblScope><biblScope unit="page" to="1971">1971</biblScope></imprint></monogr><idno type="istex">3070736F0F60F59E6E6CD41354614296883642EF</idno><idno type="DOI">10.1002/mds.21703</idno><idno type="ArticleID">MDS21703</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Graves' disease</term></item><item><term>stiff person syndrome</term></item><item><term>ataxia</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-06-22">Received</change><change when="2007-07-18">Registration</change><change when="2007-10-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3070736F0F60F59E6E6CD41354614296883642EF/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="130"><doi origin="wiley" registered="yes">10.1002/mds.v22:13</doi><numberingGroup><numbering type="journalVolume" number="22">22</numbering><numbering type="journalIssue">13</numbering></numberingGroup><coverDate startDate="2007-10-15">15 October 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="220" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.21703</doi><idGroup><id type="unit" value="MDS21703"></id></idGroup><countGroup><count type="pageTotal" number="3"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2007 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2007-06-22"></event><event type="manuscriptRevised" date="2007-07-16"></event><event type="manuscriptAccepted" date="2007-07-18"></event><event type="firstOnline" date="2007-08-21"></event><event type="publishedOnlineFinalForm" date="2007-10-26"></event><event type="publishedOnlineAcceptedOrEarlyUnpaginated" date="2007-08-21"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.4.7 mode:FullText source:FullText result:FullText" date="2011-02-24"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">1969</numbering><numbering type="pageLast">1971</numbering></numberingGroup><correspondenceTo>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS21703.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="12"></count><count type="wordTotal" number="1660"></count></countGroup><titleGroup><title type="main" xml:lang="en">Acute ataxia, Graves' disease, and stiff person syndrome</title><title type="short" xml:lang="en">Acute Ataxia, Graves' Disease, and SPS</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>Su‐Ynn</givenNames><familyName>Chia</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Richard</givenNames><familyName>Chua</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Yew‐Long</givenNames><familyName>Lo</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Meng‐Cheong</givenNames><familyName>Wong</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Ling‐Ling</givenNames><familyName>Chan</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Eng‐King</givenNames><familyName>Tan</familyName><degrees>MD</degrees></personName><contactDetails><email>gnrtek@sgh.com.sg</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="SG" type="organization"><unparsedAffiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="SG" type="organization"><unparsedAffiliation>Department of Endocrinology, Singapore General Hospital, Singapore</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="SG" type="organization"><unparsedAffiliation>Department of Radiology, Singapore General Hospital, Singapore</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Graves' disease</keyword><keyword xml:id="kwd2">stiff person syndrome</keyword><keyword xml:id="kwd3">ataxia</keyword></keywordGroup><supportingInformation><p> This article includes supplementary video clips, available online at <url href="http://www.interscience.wiley.com/jpages/0885-3185/suppmat"> http://www.interscience.wiley.com/jpages/0885‐3185/suppmat </url></p><supportingInfoItem><mediaResource alt="supporting information" href="urn-x:wiley:08853185:media:mds21703:mds21703-MDS21703"></mediaResource><caption>Segment 1. The patient presented with an acute onset of slurred speech and unsteady gait. She had evidence of poor coordination manifested by bilateral dysmetria, dysdiadochokinesia, and truncal ataxia.Segment 2. The patient had a dysarthric speech.Segment 3. The patient had a markedly increased extensor tone in her neck and trunk, together with a broad‐based gait and extremely poor balance requiring assistance to walk.</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 3-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Acute ataxia, Graves' disease, and stiff person syndrome</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Acute Ataxia, Graves' Disease, and SPS</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Acute ataxia, Graves' disease, and stiff person syndrome</title></titleInfo><name type="personal"><namePart type="given">Su‐Ynn</namePart><namePart type="family">Chia</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><affiliation>Department of Endocrinology, Singapore General Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Richard</namePart><namePart type="family">Chua</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yew‐Long</namePart><namePart type="family">Lo</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Meng‐Cheong</namePart><namePart type="family">Wong</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ling‐Ling</namePart><namePart type="family">Chan</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Radiology, Singapore General Hospital, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eng‐King</namePart><namePart type="family">Tan</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore</affiliation><description>Correspondence: Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-10-15</dateIssued><dateCaptured encoding="w3cdtf">2007-06-22</dateCaptured><dateValid encoding="w3cdtf">2007-07-18</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">1</extent><extent unit="references">12</extent><extent unit="words">1660</extent></physicalDescription><abstract lang="en">Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Graves' disease</topic><topic>stiff person syndrome</topic><topic>ataxia</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><note type="content"> This article includes supplementary video clips, available online at http://www.interscience.wiley.com/jpages/0885‐3185/suppmatSupporting Info Item: Segment 1. The patient presented with an acute onset of slurred speech and unsteady gait. She had evidence of poor coordination manifested by bilateral dysmetria, dysdiadochokinesia, and truncal ataxia.Segment 2. The patient had a dysarthric speech.Segment 3. The patient had a markedly increased extensor tone in her neck and trunk, together with a broad‐based gait and extremely poor balance requiring assistance to walk. - </note><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>13</number></detail><extent unit="pages"><start>1969</start><end>1971</end><total>3</total></extent></part></relatedItem><identifier type="istex">3070736F0F60F59E6E6CD41354614296883642EF</identifier><identifier type="DOI">10.1002/mds.21703</identifier><identifier type="ArticleID">MDS21703</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003628 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 003628 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:3070736F0F60F59E6E6CD41354614296883642EF
|texte= Acute ataxia, Graves' disease, and stiff person syndrome
}}
| This area was generated with Dilib version V0.6.23. |  |