Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients
Identifieur interne : 002C19 ( Main/Curation ); précédent : 002C18; suivant : 002C20Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients
Auteurs : Anja Weyer [Allemagne] ; Michael Abele [Allemagne] ; Tanja Schmitz-Hübsch [Allemagne] ; Beate Schoch [Allemagne] ; Markus Frings [Allemagne] ; Dagmar Timmann [Allemagne] ; Thomas Klockgether [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-08-15.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adolescent, Adult, Ataxia, Ataxia (diagnosis), Ataxia (physiopathology), Evaluation scale, Female, Health Status Indicators, Human, Humans, Male, Middle Aged, Nervous system diseases, Outcome Assessment (Health Care) (methods), Reliability, Reproducibility of Results, SARA reliability, Sensitivity and Specificity, Severity of Illness Index, Validity, ataxia, clinical assessment.
- MESH :
- diagnosis : Ataxia.
- methods : Outcome Assessment (Health Care).
- physiopathology : Ataxia.
- Adolescent, Adult, Female, Health Status Indicators, Humans, Male, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index.
Abstract
The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21544
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ISTEX:3F9BADDF48F84B5EE6369A91174635D4E3A4B988Le document en format XML
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<front><div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.</div>
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<front><div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</div>
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