Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients
Identifieur interne : 001F13 ( Istex/Corpus ); précédent : 001F12; suivant : 001F14Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients
Auteurs : Anja Weyer ; Michael Abele ; Tanja Schmitz-Hübsch ; Beate Schoch ; Markus Frings ; Dagmar Timmann ; Thomas KlockgetherSource :
- Movement Disorders [ 0885-3185 ] ; 2007-08-15.
English descriptors
- KwdEn :
Abstract
The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21544
Links to Exploration step
ISTEX:3F9BADDF48F84B5EE6369A91174635D4E3A4B988Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title><author><name sortKey="Weyer, Anja" sort="Weyer, Anja" uniqKey="Weyer A" first="Anja" last="Weyer">Anja Weyer</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schmitz Bsch, Tanja" sort="Schmitz Bsch, Tanja" uniqKey="Schmitz Bsch T" first="Tanja" last="Schmitz-Hübsch">Tanja Schmitz-Hübsch</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schoch, Beate" sort="Schoch, Beate" uniqKey="Schoch B" first="Beate" last="Schoch">Beate Schoch</name><affiliation><mods:affiliation>Department of Neurosurgery, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Frings, Markus" sort="Frings, Markus" uniqKey="Frings M" first="Markus" last="Frings">Markus Frings</name><affiliation><mods:affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Timmann, Dagmar" sort="Timmann, Dagmar" uniqKey="Timmann D" first="Dagmar" last="Timmann">Dagmar Timmann</name><affiliation><mods:affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3F9BADDF48F84B5EE6369A91174635D4E3A4B988</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21544</idno><idno type="url">https://api.istex.fr/document/3F9BADDF48F84B5EE6369A91174635D4E3A4B988/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001F13</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title><author><name sortKey="Weyer, Anja" sort="Weyer, Anja" uniqKey="Weyer A" first="Anja" last="Weyer">Anja Weyer</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schmitz Bsch, Tanja" sort="Schmitz Bsch, Tanja" uniqKey="Schmitz Bsch T" first="Tanja" last="Schmitz-Hübsch">Tanja Schmitz-Hübsch</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schoch, Beate" sort="Schoch, Beate" uniqKey="Schoch B" first="Beate" last="Schoch">Beate Schoch</name><affiliation><mods:affiliation>Department of Neurosurgery, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Frings, Markus" sort="Frings, Markus" uniqKey="Frings M" first="Markus" last="Frings">Markus Frings</name><affiliation><mods:affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Timmann, Dagmar" sort="Timmann, Dagmar" uniqKey="Timmann D" first="Dagmar" last="Timmann">Dagmar Timmann</name><affiliation><mods:affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name><affiliation><mods:affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-08-15">2007-08-15</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1633">1633</biblScope><biblScope unit="page" to="1637">1637</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">3F9BADDF48F84B5EE6369A91174635D4E3A4B988</idno><idno type="DOI">10.1002/mds.21544</idno><idno type="ArticleID">MDS21544</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>SARA reliability</term><term>ataxia</term><term>clinical assessment</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Anja Weyer MD</name><affiliations><json:string>Department of Neurology, University Hospital of Bonn, Bonn, Germany</json:string></affiliations></json:item><json:item><name>Michael Abele MD</name><affiliations><json:string>Department of Neurology, University Hospital of Bonn, Bonn, Germany</json:string></affiliations></json:item><json:item><name>Tanja Schmitz‐Hübsch MD</name><affiliations><json:string>Department of Neurology, University Hospital of Bonn, Bonn, Germany</json:string></affiliations></json:item><json:item><name>Beate Schoch MD</name><affiliations><json:string>Department of Neurosurgery, University Hospital Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Markus Frings MD</name><affiliations><json:string>Department of Neurology, University Hospital Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Dagmar Timmann MD</name><affiliations><json:string>Department of Neurology, University Hospital Essen, Essen, Germany</json:string></affiliations></json:item><json:item><name>Thomas Klockgether MD</name><affiliations><json:string>Department of Neurology, University Hospital of Bonn, Bonn, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>ataxia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>clinical assessment</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>SARA reliability</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P > 0.0001) and was closely correlated with Barthel index (r = −0.63, P > 0.0001) and UHDRS‐IV (r = −0.62, P > 0.0001), but only weakly correlated with disease duration (r = 0.44, P > 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</abstract><qualityIndicators><score>5.371</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1261</abstractCharCount><pdfWordCount>2983</pdfWordCount><pdfCharCount>19303</pdfCharCount><pdfPageCount>5</pdfPageCount><abstractWordCount>199</abstractWordCount></qualityIndicators><title>Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title><genre><json:string>Serial article</json:string></genre><host><volume>22</volume><pages><total>4</total><last>1637</last><first>1633</first></pages><issn><json:string>0885-3185</json:string></issn><issue>11</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><publicationDate>2007</publicationDate><copyrightDate>2007</copyrightDate><doi><json:string>10.1002/mds.21544</json:string></doi><id>3F9BADDF48F84B5EE6369A91174635D4E3A4B988</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/3F9BADDF48F84B5EE6369A91174635D4E3A4B988/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/3F9BADDF48F84B5EE6369A91174635D4E3A4B988/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3F9BADDF48F84B5EE6369A91174635D4E3A4B988/fulltext/tei"><teiHeader type="text"><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Wiley Subscription Services, Inc., A Wiley Company</p></availability><date>2007</date></publicationStmt><notesStmt><note>European Community (EUROSCA) - No. LSHM‐CT‐2004–503304;</note><note>German Ministry of Education and Research (GeneMove) - No. 01 GM 0503;</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title><author><persName><forename type="first">Anja</forename><surname>Weyer</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation></author><author><persName><forename type="first">Michael</forename><surname>Abele</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation></author><author><persName><forename type="first">Tanja</forename><surname>Schmitz‐Hübsch</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation></author><author><persName><forename type="first">Beate</forename><surname>Schoch</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurosurgery, University Hospital Essen, Essen, Germany</affiliation></author><author><persName><forename type="first">Markus</forename><surname>Frings</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</affiliation></author><author><persName><forename type="first">Dagmar</forename><surname>Timmann</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</affiliation></author><author><persName><forename type="first">Thomas</forename><surname>Klockgether</surname><roleName type="degree">MD</roleName></persName><note type="correspondence"><p>Correspondence: Department of Neurology, University Hospital of Bonn, Sigmund‐Freud‐Str. 25, D‐53105 Bonn, Germany</p></note><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-08-15"></date><biblScope unit="vol">22</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1633">1633</biblScope><biblScope unit="page" to="1637">1637</biblScope></imprint></monogr><idno type="istex">3F9BADDF48F84B5EE6369A91174635D4E3A4B988</idno><idno type="DOI">10.1002/mds.21544</idno><idno type="ArticleID">MDS21544</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>ataxia</term></item><item><term>clinical assessment</term></item><item><term>SARA reliability</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-02-05">Received</change><change when="2007-04-01">Registration</change><change when="2007-08-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/3F9BADDF48F84B5EE6369A91174635D4E3A4B988/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="110"><doi origin="wiley" registered="yes">10.1002/mds.v22:11</doi><numberingGroup><numbering type="journalVolume" number="22">22</numbering><numbering type="journalIssue">11</numbering></numberingGroup><coverDate startDate="2007-08-15">15 August 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="180" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.21544</doi><idGroup><id type="unit" value="MDS21544"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2007 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2007-02-05"></event><event type="manuscriptRevised" date="2007-03-30"></event><event type="manuscriptAccepted" date="2007-04-01"></event><event type="publishedOnlineEarlyUnpaginated" date="2007-05-21"></event><event type="firstOnline" date="2007-05-21"></event><event type="publishedOnlineFinalForm" date="2007-08-29"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">1633</numbering><numbering type="pageLast">1637</numbering></numberingGroup><correspondenceTo>Department of Neurology, University Hospital of Bonn, Sigmund‐Freud‐Str. 25, D‐53105 Bonn, Germany</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS21544.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="2"></count><count type="referenceTotal" number="12"></count><count type="wordTotal" number="2423"></count></countGroup><titleGroup><title type="main" xml:lang="en">Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title><title type="short" xml:lang="en">Reliability and Validity of the SARA in Ataxia</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Anja</givenNames><familyName>Weyer</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Michael</givenNames><familyName>Abele</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Tanja</givenNames><familyName>Schmitz‐Hübsch</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Beate</givenNames><familyName>Schoch</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Markus</givenNames><familyName>Frings</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Dagmar</givenNames><familyName>Timmann</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Thomas</givenNames><familyName>Klockgether</familyName><degrees>MD</degrees></personName><contactDetails><email normalForm="klockgether@uni-bonn.de">klockgether@uni‐bonn.de</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurosurgery, University Hospital Essen, Essen, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="DE" type="organization"><unparsedAffiliation>Department of Neurology, University Hospital Essen, Essen, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">ataxia</keyword><keyword xml:id="kwd2">clinical assessment</keyword><keyword xml:id="kwd3">SARA reliability</keyword></keywordGroup><fundingInfo><fundingAgency>European Community (EUROSCA)</fundingAgency><fundingNumber>LSHM‐CT‐2004–503304</fundingNumber></fundingInfo><fundingInfo><fundingAgency>German Ministry of Education and Research (GeneMove)</fundingAgency><fundingNumber>01 GM 0503</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (<i>P</i> < 0.0001) and was closely correlated with Barthel index (r = −0.63, <i>P</i> < 0.0001) and UHDRS‐IV (r = −0.62, <i>P</i> < 0.0001), but only weakly correlated with disease duration (r = 0.44, <i>P</i> < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Reliability and Validity of the SARA in Ataxia</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients</title></titleInfo><name type="personal"><namePart type="given">Anja</namePart><namePart type="family">Weyer</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michael</namePart><namePart type="family">Abele</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Tanja</namePart><namePart type="family">Schmitz‐Hübsch</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Beate</namePart><namePart type="family">Schoch</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurosurgery, University Hospital Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Markus</namePart><namePart type="family">Frings</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dagmar</namePart><namePart type="family">Timmann</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital Essen, Essen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Thomas</namePart><namePart type="family">Klockgether</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, University Hospital of Bonn, Bonn, Germany</affiliation><description>Correspondence: Department of Neurology, University Hospital of Bonn, Sigmund‐Freud‐Str. 25, D‐53105 Bonn, Germany</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-08-15</dateIssued><dateCaptured encoding="w3cdtf">2007-02-05</dateCaptured><dateValid encoding="w3cdtf">2007-04-01</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">2</extent><extent unit="references">12</extent><extent unit="words">2423</extent></physicalDescription><abstract lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS‐IV). Eighteen patients were rated twice. Inter‐rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = −0.63, P < 0.0001) and UHDRS‐IV (r = −0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non‐SCA ataxia patients. © 2007 Movement Disorder Society</abstract><note type="funding">European Community (EUROSCA) - No. LSHM‐CT‐2004–503304; </note><note type="funding">German Ministry of Education and Research (GeneMove) - No. 01 GM 0503; </note><subject lang="en"><genre>Keywords</genre><topic>ataxia</topic><topic>clinical assessment</topic><topic>SARA reliability</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>11</number></detail><extent unit="pages"><start>1633</start><end>1637</end><total>4</total></extent></part></relatedItem><identifier type="istex">3F9BADDF48F84B5EE6369A91174635D4E3A4B988</identifier><identifier type="DOI">10.1002/mds.21544</identifier><identifier type="ArticleID">MDS21544</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F13 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001F13 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:3F9BADDF48F84B5EE6369A91174635D4E3A4B988
|texte= Reliability and validity of the scale for the assessment and rating of ataxia: A study in 64 ataxia patients
}}
| This area was generated with Dilib version V0.6.23. |  |