Movement Disorders (revue)

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Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Identifieur interne : 001559 ( PascalFrancis/Corpus ); précédent : 001558; suivant : 001560

Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Auteurs : Anja Weyer ; Michael Abele ; Tanja Schmitz-Hübsch ; Beate Schoch ; Markus Frings ; Dagmar Timmann ; Thomas Klockgether

Source :

RBID : Pascal:07-0448801

Descripteurs français

English descriptors

Abstract

The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Mov. disord.
A05       @2 22
A06       @2 11
A08 01  1  ENG  @1 Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients
A11 01  1    @1 WEYER (Anja)
A11 02  1    @1 ABELE (Michael)
A11 03  1    @1 SCHMITZ-HÜBSCH (Tanja)
A11 04  1    @1 SCHOCH (Beate)
A11 05  1    @1 FRINGS (Markus)
A11 06  1    @1 TIMMANN (Dagmar)
A11 07  1    @1 KLOCKGETHER (Thomas)
A14 01      @1 Department of Neurology, University Hospital of Bonn @2 Bonn @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 7 aut.
A14 02      @1 Department of Neurosurgery, University Hospital Essen @2 Essen @3 DEU @Z 4 aut.
A14 03      @1 Department of Neurology, University Hospital Essen @2 Essen @3 DEU @Z 5 aut. @Z 6 aut.
A20       @1 1633-1637
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000149744800180
A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
A45       @0 12 ref.
A47 01  1    @0 07-0448801
A60       @1 P @3 CC
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.
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C03 02  X  ENG  @0 Ataxia @5 02
C03 02  X  SPA  @0 Ataxia @5 02
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C03 03  X  ENG  @0 Reliability @5 09
C03 03  X  SPA  @0 Fiabilidad @5 09
C03 04  X  FRE  @0 Validité @5 10
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C07 02  X  SPA  @0 Sistema nervosio central patología @5 38
C07 03  X  FRE  @0 Trouble neurologique @5 39
C07 03  X  ENG  @0 Neurological disorder @5 39
C07 03  X  SPA  @0 Trastorno neurológico @5 39
N21       @1 295
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 07-0448801 INIST
ET : Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients
AU : WEYER (Anja); ABELE (Michael); SCHMITZ-HÜBSCH (Tanja); SCHOCH (Beate); FRINGS (Markus); TIMMANN (Dagmar); KLOCKGETHER (Thomas)
AF : Department of Neurology, University Hospital of Bonn/Bonn/Allemagne (1 aut., 2 aut., 3 aut., 7 aut.); Department of Neurosurgery, University Hospital Essen/Essen/Allemagne (4 aut.); Department of Neurology, University Hospital Essen/Essen/Allemagne (5 aut., 6 aut.)
DT : Publication en série; Courte communication, note brève; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 11; Pp. 1633-1637; Bibl. 12 ref.
LA : Anglais
EA : The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.
CC : 002B17; 002B17F; 002B17G
FD : Système nerveux pathologie; Ataxie; Fiabilité; Validité; Echelle d'évaluation; Homme
FG : Encéphale pathologie; Système nerveux central pathologie; Trouble neurologique
ED : Nervous system diseases; Ataxia; Reliability; Validity; Evaluation scale; Human
EG : Cerebral disorder; Central nervous system disease; Neurological disorder
SD : Sistema nervioso patología; Ataxia; Fiabilidad; Validez; Escala evaluación; Hombre
LO : INIST-20953.354000149744800180
ID : 07-0448801

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Pascal:07-0448801

Le document en format XML

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<div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.</div>
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<NO>PASCAL 07-0448801 INIST</NO>
<ET>Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients</ET>
<AU>WEYER (Anja); ABELE (Michael); SCHMITZ-HÜBSCH (Tanja); SCHOCH (Beate); FRINGS (Markus); TIMMANN (Dagmar); KLOCKGETHER (Thomas)</AU>
<AF>Department of Neurology, University Hospital of Bonn/Bonn/Allemagne (1 aut., 2 aut., 3 aut., 7 aut.); Department of Neurosurgery, University Hospital Essen/Essen/Allemagne (4 aut.); Department of Neurology, University Hospital Essen/Essen/Allemagne (5 aut., 6 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 11; Pp. 1633-1637; Bibl. 12 ref.</SO>
<LA>Anglais</LA>
<EA>The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.</EA>
<CC>002B17; 002B17F; 002B17G</CC>
<FD>Système nerveux pathologie; Ataxie; Fiabilité; Validité; Echelle d'évaluation; Homme</FD>
<FG>Encéphale pathologie; Système nerveux central pathologie; Trouble neurologique</FG>
<ED>Nervous system diseases; Ataxia; Reliability; Validity; Evaluation scale; Human</ED>
<EG>Cerebral disorder; Central nervous system disease; Neurological disorder</EG>
<SD>Sistema nervioso patología; Ataxia; Fiabilidad; Validez; Escala evaluación; Hombre</SD>
<LO>INIST-20953.354000149744800180</LO>
<ID>07-0448801</ID>
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