MovDisordV3, Main, Merge, bibRecord, 004078

Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Identifieur interne : 004078 ( Main/Merge ); précédent : 004077; suivant : 004079

Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Auteurs : Anja Weyer [Allemagne] ; Michael Abele [Allemagne] ; Tanja Schmitz-Hübsch [Allemagne] ; Beate Schoch [Allemagne] ; Markus Frings [Allemagne] ; Dagmar Timmann [Allemagne] ; Thomas Klockgether [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:07-0448801

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Ataxie, Fiabilité, Validité, Echelle d'évaluation, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Ataxia, Evaluation scale, Human, Nervous system diseases, Reliability, Validity.

Abstract

The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.

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Pascal:07-0448801

Le document en format XML

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<front><div type="abstract" xml:lang="en">The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. In addition to SARA, the following assessment instruments were applied: ataxia disease stage, Barthel index and part IV (functional assessment) of the Unified Huntington's Disease Rating scale (UHDRS-IV). Eighteen patients were rated twice. Inter-rater and intrarater reliability were very high with ICCs of 0.98 and 0.99. Internal consistency was high indicated by Cronbach's α of 0.97. Factorial analysis revealed that the rating results were mainly determined by one major factor with an eigenvalue of 6.34 which explained 52.8% of the variance. SARA score increased with disease stage (P < 0.0001) and was closely correlated with Barthel index (r = -0.63, P < 0.0001) and UHDRS-IV (r = -0.62, P < 0.0001), but only weakly correlated with disease duration (r = 0.44, P < 0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients.</div>
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<tree><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Weyer, Anja" sort="Weyer, Anja" uniqKey="Weyer A" first="Anja" last="Weyer">Anja Weyer</name>
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<name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<name sortKey="Frings, Markus" sort="Frings, Markus" uniqKey="Frings M" first="Markus" last="Frings">Markus Frings</name>
<name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
<name sortKey="Schmitz Hubsch, Tanja" sort="Schmitz Hubsch, Tanja" uniqKey="Schmitz Hubsch T" first="Tanja" last="Schmitz-Hübsch">Tanja Schmitz-Hübsch</name>
<name sortKey="Schoch, Beate" sort="Schoch, Beate" uniqKey="Schoch B" first="Beate" last="Schoch">Beate Schoch</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Reliability and validity of the scale for the assessment and rating of ataxia : A study in 64 ataxia patients

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri