THz Medical Imaging: in vivo Hydration Sensing
Identifieur interne : 002935 ( Main/Exploration ); précédent : 002934; suivant : 002936THz Medical Imaging: in vivo Hydration Sensing
Auteurs : Zachary D. Taylor ; Rahul S. Singh ; David B. Bennett ; Priyamvada Tewari ; Colin P. Kealey ; Neha Bajwa ; Martin O. Culjat ; Alexander Stojadinovic ; Hua Lee ; Jean-Pierre Hubschman ; Elliott R. Brown ; Warren S. GrundfestSource :
- IEEE transactions on terahertz science and technology [ 2156-342X ] ; 2011.
Abstract
The application of THz to medical imaging is experiencing a surge in both interest and federal funding. A brief overview of the field is provided along with promising and emerging applications and ongoing research. THz imaging phenomenology is discussed and tradeoffs are identified. A THz medical imaging system, operating at ~525 GHz center frequency with ~125 GHz of response normalized bandwidth is introduced and details regarding principles of operation are provided. Two promising medical applications of THz imaging are presented: skin burns and cornea. For burns, images of second degree, partial thickness burns were obtained in rat models
Url:
DOI: 10.1109/TTHZ.2011.2159551
PubMed: 26085958
PubMed Central: 4467694
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p id="P1">The application of THz to medical imaging is experiencing a surge in both interest and federal funding. A brief overview of the field is provided along with promising and emerging applications and ongoing research. THz imaging phenomenology is discussed and tradeoffs are identified. A THz medical imaging system, operating at ~525 GHz center frequency with ~125 GHz of response normalized bandwidth is introduced and details regarding principles of operation are provided. Two promising medical applications of THz imaging are presented: skin burns and cornea. For burns, images of second degree, partial thickness burns were obtained in rat models <italic>in vivo</italic>
over an 8 hour period. These images clearly show the formation and progression of edema in and around the burn wound area. For cornea, experimental data measuring the hydration of <italic>ex vivo</italic>
porcine cornea under drying is presented demonstrating utility in ophthalmologic applications.</p>
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<name sortKey="Brown, Elliott R" sort="Brown, Elliott R" uniqKey="Brown E" first="Elliott R." last="Brown">Elliott R. Brown</name>
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<name sortKey="Grundfest, Warren S" sort="Grundfest, Warren S" uniqKey="Grundfest W" first="Warren S." last="Grundfest">Warren S. Grundfest</name>
<name sortKey="Hubschman, Jean Pierre" sort="Hubschman, Jean Pierre" uniqKey="Hubschman J" first="Jean-Pierre" last="Hubschman">Jean-Pierre Hubschman</name>
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<name sortKey="Lee, Hua" sort="Lee, Hua" uniqKey="Lee H" first="Hua" last="Lee">Hua Lee</name>
<name sortKey="Singh, Rahul S" sort="Singh, Rahul S" uniqKey="Singh R" first="Rahul S." last="Singh">Rahul S. Singh</name>
<name sortKey="Stojadinovic, Alexander" sort="Stojadinovic, Alexander" uniqKey="Stojadinovic A" first="Alexander" last="Stojadinovic">Alexander Stojadinovic</name>
<name sortKey="Taylor, Zachary D" sort="Taylor, Zachary D" uniqKey="Taylor Z" first="Zachary D." last="Taylor">Zachary D. Taylor</name>
<name sortKey="Tewari, Priyamvada" sort="Tewari, Priyamvada" uniqKey="Tewari P" first="Priyamvada" last="Tewari">Priyamvada Tewari</name>
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