SrasV1, Main, Exploration, bibRecord, 004476

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)

Identifieur interne : 004476 ( Main/Exploration ); précédent : 004475; suivant : 004477

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)

Auteurs : Chung K. Chu [États-Unis] ; Srinivas Gadthula [États-Unis] ; XIN CHEN [États-Unis] ; HYUNAH CHOO [États-Unis] ; Sureyya Olgen [États-Unis] ; Dale L. Barnard [États-Unis] ; Robert W. Sidwell [États-Unis]

Source :

Antiviral chemistry & chemotherapy [ 0956-3202 ] ; 2006.

RBID : Pascal:07-0101457

Descripteurs français

KwdFr :
- Animaux, Antiviraux (), Antiviraux (pharmacologie), Cellules Vero, Nucléosides (), Nucléosides (pharmacologie), Relation structure-activité, Réplication virale (), Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS ().
MESH :
- pharmacologie : Antiviraux, Nucléosides.
Pascal (Inist)
- Animaux, Antiviral, Analogue nucléoside, Antiviraux, Cellules Vero, Nucléosides, Relation structure-activité, Réplication virale, Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS, Virus syndrome respiratoire aigu sévère, Syndrome respiratoire aigu sévère, In vitro, Activité biologique.

English descriptors

KwdEn :
- Animals, Antiviral, Antiviral Agents (chemistry), Antiviral Agents (pharmacology), Biological activity, Chlorocebus aethiops, In vitro, Microbial Sensitivity Tests, Molecular Structure, Nucleoside analog, Nucleosides (chemistry), Nucleosides (pharmacology), SARS Virus (drug effects), Severe acute respiratory syndrome, Severe acute respiratory syndrome virus, Structure-Activity Relationship, Vero Cells, Virus Replication (drug effects).
MESH :
- chemical , chemistry : Antiviral Agents, Nucleosides.
- chemical , pharmacology : Antiviral Agents, Nucleosides.
- drug effects : SARS Virus, Virus Replication.
- Animals, Chlorocebus aethiops, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Vero Cells.

Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

Affiliations:

Le document en format XML

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<term>Antiviral Agents (pharmacology)</term>
<term>Biological activity</term>
<term>Chlorocebus aethiops</term>
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<term>Nucleosides (pharmacology)</term>
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<front><div type="abstract" xml:lang="en">The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.</div>
</front>
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<tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Chu, Chung K" sort="Chu, Chung K" uniqKey="Chu C" first="Chung K." last="Chu">Chung K. Chu</name>
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<name sortKey="Gadthula, Srinivas" sort="Gadthula, Srinivas" uniqKey="Gadthula S" first="Srinivas" last="Gadthula">Srinivas Gadthula</name>
<name sortKey="Hyunah Choo" sort="Hyunah Choo" uniqKey="Hyunah Choo" last="Hyunah Choo">HYUNAH CHOO</name>
<name sortKey="Olgen, Sureyya" sort="Olgen, Sureyya" uniqKey="Olgen S" first="Sureyya" last="Olgen">Sureyya Olgen</name>
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<name sortKey="Xin Chen" sort="Xin Chen" uniqKey="Xin Chen" last="Xin Chen">XIN CHEN</name>
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Serveur d'exploration SRAS

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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