Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)
Identifieur interne : 000505 ( PascalFrancis/Checkpoint ); précédent : 000504; suivant : 000506Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)
Auteurs : Chung K. Chu [États-Unis] ; Srinivas Gadthula [États-Unis] ; XIN CHEN [États-Unis] ; HYUNAH CHOO [États-Unis] ; Sureyya Olgen [États-Unis] ; Dale L. Barnard [États-Unis] ; Robert W. Sidwell [États-Unis]Source :
- Antiviral chemistry & chemotherapy [ 0956-3202 ] ; 2006.
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Abstract
The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.
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Chu</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Gadthula, Srinivas" sort="Gadthula, Srinivas" uniqKey="Gadthula S" first="Srinivas" last="Gadthula">Srinivas Gadthula</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Xin Chen" sort="Xin Chen" uniqKey="Xin Chen" last="Xin Chen">XIN CHEN</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Hyunah Choo" sort="Hyunah Choo" uniqKey="Hyunah Choo" last="Hyunah Choo">HYUNAH CHOO</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Olgen, Sureyya" sort="Olgen, Sureyya" uniqKey="Olgen S" first="Sureyya" last="Olgen">Sureyya Olgen</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. 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Chu</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Gadthula, Srinivas" sort="Gadthula, Srinivas" uniqKey="Gadthula S" first="Srinivas" last="Gadthula">Srinivas Gadthula</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Xin Chen" sort="Xin Chen" uniqKey="Xin Chen" last="Xin Chen">XIN CHEN</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Hyunah Choo" sort="Hyunah Choo" uniqKey="Hyunah Choo" last="Hyunah Choo">HYUNAH CHOO</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Olgen, Sureyya" sort="Olgen, Sureyya" uniqKey="Olgen S" first="Sureyya" last="Olgen">Sureyya Olgen</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. Barnard</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Institute of Antiviral Research, Utah State University</s1><s2>Logan, UT</s2><s3>USA</s3><sZ>6 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Sidwell, Robert W" sort="Sidwell, Robert W" uniqKey="Sidwell R" first="Robert W." last="Sidwell">Robert W. Sidwell</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Institute of Antiviral Research, Utah State University</s1><s2>Logan, UT</s2><s3>USA</s3><sZ>6 aut.</sZ><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Utah</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Antiviral chemistry & chemotherapy</title><title level="j" type="abbreviated">Antivir. chem. chemother.</title><idno type="ISSN">0956-3202</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Antiviral chemistry & chemotherapy</title><title level="j" type="abbreviated">Antivir. chem. chemother.</title><idno type="ISSN">0956-3202</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral</term><term>Biological activity</term><term>In vitro</term><term>Nucleoside analog</term><term>Severe acute respiratory syndrome</term><term>Severe acute respiratory syndrome virus</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Antiviral</term><term>Analogue nucléoside</term><term>Virus syndrome respiratoire aigu sévère</term><term>Syndrome respiratoire aigu sévère</term><term>In vitro</term><term>Activité biologique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0956-3202</s0></fA01><fA03 i2="1"><s0>Antivir. chem. chemother.</s0></fA03><fA05><s2>17</s2></fA05><fA06><s2>5</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)</s1></fA08><fA11 i1="01" i2="1"><s1>CHU (Chung K.)</s1></fA11><fA11 i1="02" i2="1"><s1>GADTHULA (Srinivas)</s1></fA11><fA11 i1="03" i2="1"><s1>XIN CHEN</s1></fA11><fA11 i1="04" i2="1"><s1>HYUNAH CHOO</s1></fA11><fA11 i1="05" i2="1"><s1>OLGEN (Sureyya)</s1></fA11><fA11 i1="06" i2="1"><s1>BARNARD (Dale L.)</s1></fA11><fA11 i1="07" i2="1"><s1>SIDWELL (Robert W.)</s1></fA11><fA14 i1="01"><s1>The University of Georgia, College of Pharmacy</s1><s2>Athens, GA</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></fA14><fA14 i1="02"><s1>Institute of Antiviral Research, Utah State University</s1><s2>Logan, UT</s2><s3>USA</s3><sZ>6 aut.</sZ><sZ>7 aut.</sZ></fA14><fA20><s1>285-289</s1></fA20><fA21><s1>2006</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>22101</s2><s5>354000159494570060</s5></fA43><fA44><s0>0000</s0><s1>© 2007 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>24 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>07-0101457</s0></fA47><fA60><s1>P</s1><s3>CC</s3></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Antiviral chemistry & chemotherapy</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). 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Chu</name></region><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. Barnard</name><name sortKey="Gadthula, Srinivas" sort="Gadthula, Srinivas" uniqKey="Gadthula S" first="Srinivas" last="Gadthula">Srinivas Gadthula</name><name sortKey="Hyunah Choo" sort="Hyunah Choo" uniqKey="Hyunah Choo" last="Hyunah Choo">HYUNAH CHOO</name><name sortKey="Olgen, Sureyya" sort="Olgen, Sureyya" uniqKey="Olgen S" first="Sureyya" last="Olgen">Sureyya Olgen</name><name sortKey="Sidwell, Robert W" sort="Sidwell, Robert W" uniqKey="Sidwell R" first="Robert W." last="Sidwell">Robert W. Sidwell</name><name sortKey="Xin Chen" sort="Xin Chen" uniqKey="Xin Chen" last="Xin Chen">XIN CHEN</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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