SrasV1, Ncbi, Merge, bibRecord, 001809

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Identifieur interne : 001809 ( Ncbi/Merge ); précédent : 001808; suivant : 001810

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Auteurs : Chung K. Chu [États-Unis] ; Srinivas Gadthula ; Xin Chen ; Hyunah Choo ; Sureyya Olgen ; Dale L. Barnard ; Robert W. Sidwell

Source :

Antiviral chemistry & chemotherapy [ 0956-3202 ] ; 2006.

RBID : pubmed:17176633

Descripteurs français

KwdFr :
- Animaux, Antiviraux (), Antiviraux (pharmacologie), Cellules Vero, Nucléosides (), Nucléosides (pharmacologie), Relation structure-activité, Réplication virale (), Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS ().
MESH :
- pharmacologie : Antiviraux, Nucléosides.
- Animaux, Antiviraux, Cellules Vero, Nucléosides, Relation structure-activité, Réplication virale, Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS.

English descriptors

KwdEn :
- Animals, Antiviral Agents (chemistry), Antiviral Agents (pharmacology), Chlorocebus aethiops, Microbial Sensitivity Tests, Molecular Structure, Nucleosides (chemistry), Nucleosides (pharmacology), SARS Virus (drug effects), Structure-Activity Relationship, Vero Cells, Virus Replication (drug effects).
MESH :
- chemical , chemistry : Antiviral Agents, Nucleosides.
- chemical , pharmacology : Antiviral Agents, Nucleosides.
- drug effects : SARS Virus, Virus Replication.
- Animals, Chlorocebus aethiops, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Vero Cells.

Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

DOI: 10.1177/095632020601700506
PubMed: 17176633

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pubmed:17176633

Le document en format XML

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<author><name sortKey="Chu, Chung K" sort="Chu, Chung K" uniqKey="Chu C" first="Chung K" last="Chu">Chung K. Chu</name>
<affiliation wicri:level="2"><nlm:affiliation>The University of Georgia, College of Pharmacy, Athens, GA, USA. dchu@rx.uga.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The University of Georgia, College of Pharmacy, Athens, GA</wicri:regionArea>
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<author><name sortKey="Gadthula, Srinivas" sort="Gadthula, Srinivas" uniqKey="Gadthula S" first="Srinivas" last="Gadthula">Srinivas Gadthula</name>
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<author><name sortKey="Chen, Xin" sort="Chen, Xin" uniqKey="Chen X" first="Xin" last="Chen">Xin Chen</name>
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<author><name sortKey="Choo, Hyunah" sort="Choo, Hyunah" uniqKey="Choo H" first="Hyunah" last="Choo">Hyunah Choo</name>
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<term>Antiviral Agents (pharmacology)</term>
<term>Chlorocebus aethiops</term>
<term>Microbial Sensitivity Tests</term>
<term>Molecular Structure</term>
<term>Nucleosides (chemistry)</term>
<term>Nucleosides (pharmacology)</term>
<term>SARS Virus (drug effects)</term>
<term>Structure-Activity Relationship</term>
<term>Vero Cells</term>
<term>Virus Replication (drug effects)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
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<term>Relation structure-activité</term>
<term>Réplication virale ()</term>
<term>Structure moléculaire</term>
<term>Tests de sensibilité microbienne</term>
<term>Virus du SRAS ()</term>
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<term>Structure-Activity Relationship</term>
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<term>Antiviraux</term>
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<term>Nucléosides</term>
<term>Relation structure-activité</term>
<term>Réplication virale</term>
<term>Structure moléculaire</term>
<term>Tests de sensibilité microbienne</term>
<term>Virus du SRAS</term>
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<front><div type="abstract" xml:lang="en">The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.</div>
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Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki