SrasV1, Ncbi, Curation, bibRecord, 001809

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Identifieur interne : 001809 ( Ncbi/Curation ); précédent : 001808; suivant : 001810

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Auteurs : Chung K. Chu [États-Unis] ; Srinivas Gadthula ; Xin Chen ; Hyunah Choo ; Sureyya Olgen ; Dale L. Barnard ; Robert W. Sidwell

Source :

Antiviral chemistry & chemotherapy [ 0956-3202 ] ; 2006.

RBID : pubmed:17176633

Descripteurs français

KwdFr :
- Animaux, Antiviraux (), Antiviraux (pharmacologie), Cellules Vero, Nucléosides (), Nucléosides (pharmacologie), Relation structure-activité, Réplication virale (), Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS ().
MESH :
- pharmacologie : Antiviraux, Nucléosides.
- Animaux, Antiviraux, Cellules Vero, Nucléosides, Relation structure-activité, Réplication virale, Structure moléculaire, Tests de sensibilité microbienne, Virus du SRAS.

English descriptors

KwdEn :
- Animals, Antiviral Agents (chemistry), Antiviral Agents (pharmacology), Chlorocebus aethiops, Microbial Sensitivity Tests, Molecular Structure, Nucleosides (chemistry), Nucleosides (pharmacology), SARS Virus (drug effects), Structure-Activity Relationship, Vero Cells, Virus Replication (drug effects).
MESH :
- chemical , chemistry : Antiviral Agents, Nucleosides.
- chemical , pharmacology : Antiviral Agents, Nucleosides.
- drug effects : SARS Virus, Virus Replication.
- Animals, Chlorocebus aethiops, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Vero Cells.

Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

DOI: 10.1177/095632020601700506
PubMed: 17176633

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pubmed:17176633

Le document en format XML

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<author><name sortKey="Chu, Chung K" sort="Chu, Chung K" uniqKey="Chu C" first="Chung K" last="Chu">Chung K. Chu</name>
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<author><name sortKey="Chen, Xin" sort="Chen, Xin" uniqKey="Chen X" first="Xin" last="Chen">Xin Chen</name>
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<author><name sortKey="Choo, Hyunah" sort="Choo, Hyunah" uniqKey="Choo H" first="Hyunah" last="Choo">Hyunah Choo</name>
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<author><name sortKey="Olgen, Sureyya" sort="Olgen, Sureyya" uniqKey="Olgen S" first="Sureyya" last="Olgen">Sureyya Olgen</name>
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<author><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L" last="Barnard">Dale L. Barnard</name>
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<author><name sortKey="Sidwell, Robert W" sort="Sidwell, Robert W" uniqKey="Sidwell R" first="Robert W" last="Sidwell">Robert W. Sidwell</name>
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<term>Antiviral Agents (pharmacology)</term>
<term>Chlorocebus aethiops</term>
<term>Microbial Sensitivity Tests</term>
<term>Molecular Structure</term>
<term>Nucleosides (chemistry)</term>
<term>Nucleosides (pharmacology)</term>
<term>SARS Virus (drug effects)</term>
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<term>Tests de sensibilité microbienne</term>
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<term>Nucleosides</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>SARS Virus</term>
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<term>Nucléosides</term>
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<term>Chlorocebus aethiops</term>
<term>Microbial Sensitivity Tests</term>
<term>Molecular Structure</term>
<term>Structure-Activity Relationship</term>
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<term>Tests de sensibilité microbienne</term>
<term>Virus du SRAS</term>
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<front><div type="abstract" xml:lang="en">The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.</div>
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Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki