Deficit in Evaluating Pre-Determinated Sequences of Script Events in Patients with Parkinson's Disease
Identifieur interne : 003F93 ( Main/Exploration ); précédent : 003F92; suivant : 003F94Deficit in Evaluating Pre-Determinated Sequences of Script Events in Patients with Parkinson's Disease
Auteurs : T. Zalla [France] ; A. Sirigu [France] ; B. Pillon [France] ; B. Dubois [France] ; J. Grafman [États-Unis] ; Yves Agid [France]Source :
- Cortex [ 0010-9452 ] ; 1998.
English descriptors
- KwdEn :
- MESH :
- physiology : Cognition, Higher Nervous Activity, Memory, Reaction Time.
- physiopathology : Corpus Striatum, Frontal Lobe, Parkinson Disease.
- Adult, Aged, Female, Humans, Male, Middle Aged, Neuropsychological Tests.
Abstract
The purpose of the present study was to assess how the striato-frontal system contributes to the manipulation of goal-directed actions. We studied a group of ten patients with Parkinson's disease (PD) in order to investigate which aspects of action knowledge processing are impaired and to define the conditions under which the deficits may occur. PD patients committed errors of sequence and inserted distractors in tasks that required them to order pre-determined events belonging to a given script in a typical sequence. Rather than attributing errors of event sequencing to a deficit of script syntax knowledge, we suggest that the difficulties manifested by PD patients were due to an impairment of a switching mechanism that is necessary for processing information in parallel.
Url:
DOI: 10.1016/S0010-9452(08)70519-7
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000C79
- to stream Istex, to step Curation: 000C77
- to stream Istex, to step Checkpoint: 001415
- to stream Main, to step Merge: 004773
- to stream PubMed, to step Corpus: 001461
- to stream PubMed, to step Curation: 001420
- to stream PubMed, to step Checkpoint: 001420
- to stream Ncbi, to step Merge: 001F45
- to stream Ncbi, to step Curation: 001F45
- to stream Ncbi, to step Checkpoint: 001F45
- to stream Main, to step Merge: 004731
- to stream Main, to step Curation: 003F93
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Deficit in Evaluating Pre-Determinated Sequences of Script Events in Patients with Parkinson's Disease</title>
<author><name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
</author>
<author><name sortKey="Sirigu, A" sort="Sirigu, A" uniqKey="Sirigu A" first="A." last="Sirigu">A. Sirigu</name>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
</author>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B." last="Dubois">B. Dubois</name>
</author>
<author><name sortKey="Grafman, J" sort="Grafman, J" uniqKey="Grafman J" first="J." last="Grafman">J. Grafman</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y." last="Agid">Yves Agid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:84DD175AACF6EA5E7E2E426D0B9F7CF21ED7588F</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1016/S0010-9452(08)70519-7</idno>
<idno type="url">https://api.istex.fr/document/84DD175AACF6EA5E7E2E426D0B9F7CF21ED7588F/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000C79</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000C79</idno>
<idno type="wicri:Area/Istex/Curation">000C77</idno>
<idno type="wicri:Area/Istex/Checkpoint">001415</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001415</idno>
<idno type="wicri:doubleKey">0010-9452:1998:Zalla T:deficit:in:evaluating</idno>
<idno type="wicri:Area/Main/Merge">004773</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9800095</idno>
<idno type="wicri:Area/PubMed/Corpus">001461</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001461</idno>
<idno type="wicri:Area/PubMed/Curation">001420</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001420</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001420</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001420</idno>
<idno type="wicri:Area/Ncbi/Merge">001F45</idno>
<idno type="wicri:Area/Ncbi/Curation">001F45</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001F45</idno>
<idno type="wicri:doubleKey">0010-9452:1998:Zalla T:deficit:in:evaluating</idno>
<idno type="wicri:Area/Main/Merge">004731</idno>
<idno type="wicri:Area/Main/Curation">003F93</idno>
<idno type="wicri:Area/Main/Exploration">003F93</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Deficit in Evaluating Pre-Determinated Sequences of Script Events in Patients with Parkinson's Disease</title>
<author><name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Inserm U. 289, Hpital de la Salptrire, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Crea Ecole Polytechnique, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Dr. Tiziana Zalla, Institut des Sciences Cognitives 67</wicri:regionArea>
<wicri:noRegion>Institut des Sciences Cognitives 67</wicri:noRegion>
<wicri:noRegion>Institut des Sciences Cognitives 67</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">France</country>
</affiliation>
</author>
<author><name sortKey="Sirigu, A" sort="Sirigu, A" uniqKey="Sirigu A" first="A." last="Sirigu">A. Sirigu</name>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Inserm U. 289, Hpital de la Salptrire, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Inserm U. 289, Hpital de la Salptrire, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B." last="Dubois">B. Dubois</name>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Inserm U. 289, Hpital de la Salptrire, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grafman, J" sort="Grafman, J" uniqKey="Grafman J" first="J." last="Grafman">J. Grafman</name>
<affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cognitive Neuroscience Section NINDS, NIH, Bethesda</wicri:regionArea>
<wicri:noRegion>Bethesda</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y." last="Agid">Yves Agid</name>
<affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>Inserm U. 289, Hpital de la Salptrire, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Cortex</title>
<title level="j" type="abbrev">CORTEX</title>
<idno type="ISSN">0010-9452</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1998">1998</date>
<biblScope unit="volume">34</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="621">621</biblScope>
<biblScope unit="page" to="627">627</biblScope>
</imprint>
<idno type="ISSN">0010-9452</idno>
</series>
<idno type="istex">84DD175AACF6EA5E7E2E426D0B9F7CF21ED7588F</idno>
<idno type="DOI">10.1016/S0010-9452(08)70519-7</idno>
<idno type="PII">S0010-9452(08)70519-7</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0010-9452</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Cognition (physiology)</term>
<term>Corpus Striatum (physiopathology)</term>
<term>Female</term>
<term>Frontal Lobe (physiopathology)</term>
<term>Higher Nervous Activity (physiology)</term>
<term>Humans</term>
<term>Male</term>
<term>Memory (physiology)</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Reaction Time (physiology)</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term>
<term>Higher Nervous Activity</term>
<term>Memory</term>
<term>Reaction Time</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Corpus Striatum</term>
<term>Frontal Lobe</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The purpose of the present study was to assess how the striato-frontal system contributes to the manipulation of goal-directed actions. We studied a group of ten patients with Parkinson's disease (PD) in order to investigate which aspects of action knowledge processing are impaired and to define the conditions under which the deficits may occur. PD patients committed errors of sequence and inserted distractors in tasks that required them to order pre-determined events belonging to a given script in a typical sequence. Rather than attributing errors of event sequencing to a deficit of script syntax knowledge, we suggest that the difficulties manifested by PD patients were due to an impairment of a switching mechanism that is necessary for processing information in parallel.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
<li>États-Unis</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
</settlement>
<orgName><li>Hôpital de la Salpêtrière</li>
</orgName>
</list>
<tree><country name="France"><region name="Île-de-France"><name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
</region>
<name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y." last="Agid">Yves Agid</name>
<name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B." last="Dubois">B. Dubois</name>
<name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
<name sortKey="Sirigu, A" sort="Sirigu, A" uniqKey="Sirigu A" first="A." last="Sirigu">A. Sirigu</name>
<name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
<name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
<name sortKey="Zalla, T" sort="Zalla, T" uniqKey="Zalla T" first="T." last="Zalla">T. Zalla</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Grafman, J" sort="Grafman, J" uniqKey="Grafman J" first="J." last="Grafman">J. Grafman</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003F93 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003F93 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:84DD175AACF6EA5E7E2E426D0B9F7CF21ED7588F |texte= Deficit in Evaluating Pre-Determinated Sequences of Script Events in Patients with Parkinson's Disease }}
![]() | This area was generated with Dilib version V0.6.29. | ![]() |