ParkinsonFranceV1, PubMed, Corpus, bibRecord, 001461

Deficit in evaluating pre-determined sequences of script events in patients with Parkinson's disease.

Identifieur interne : 001461 ( PubMed/Corpus ); précédent : 001460; suivant : 001462

Deficit in evaluating pre-determined sequences of script events in patients with Parkinson's disease.

Auteurs : T. Zalla ; A. Sirigu ; B. Pillon ; B. Dubois ; J. Grafman ; Y. Agid

Source :

Cortex; a journal devoted to the study of the nervous system and behavior [ 0010-9452 ] ; 1998.

RBID : pubmed:9800095

English descriptors

KwdEn :
- Adult, Aged, Cognition (physiology), Corpus Striatum (physiopathology), Female, Frontal Lobe (physiopathology), Higher Nervous Activity (physiology), Humans, Male, Memory (physiology), Middle Aged, Neuropsychological Tests, Parkinson Disease (physiopathology), Reaction Time (physiology).
MESH :
- physiology : Cognition, Higher Nervous Activity, Memory, Reaction Time.
- physiopathology : Corpus Striatum, Frontal Lobe, Parkinson Disease.
- Adult, Aged, Female, Humans, Male, Middle Aged, Neuropsychological Tests.

Abstract

The purpose of the present study was to assess how the striato-frontal system contributes to the manipulation of goal-directed actions. We studied a group of ten patients with Parkinson's disease (PD) in order to investigate which aspects of action knowledge processing are impaired and to define the conditions under which the deficits may occur. PD patients committed errors of sequence and inserted distractors in tasks that required them to order pre-determined events belonging to a given script in a typical sequence. Rather than attributing errors of event sequencing to a deficit of script "syntax" knowledge, we suggest that the difficulties manifested by PD patients were due to an impairment of a switching mechanism that is necessary for processing information in parallel.

PubMed: 9800095

Links to Exploration step

pubmed:9800095

Le document en format XML

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<author><name sortKey="Sirigu, A" sort="Sirigu, A" uniqKey="Sirigu A" first="A" last="Sirigu">A. Sirigu</name>
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<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
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<front><div type="abstract" xml:lang="en">The purpose of the present study was to assess how the striato-frontal system contributes to the manipulation of goal-directed actions. We studied a group of ten patients with Parkinson's disease (PD) in order to investigate which aspects of action knowledge processing are impaired and to define the conditions under which the deficits may occur. PD patients committed errors of sequence and inserted distractors in tasks that required them to order pre-determined events belonging to a given script in a typical sequence. Rather than attributing errors of event sequencing to a deficit of script "syntax" knowledge, we suggest that the difficulties manifested by PD patients were due to an impairment of a switching mechanism that is necessary for processing information in parallel.</div>
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<Abstract><AbstractText>The purpose of the present study was to assess how the striato-frontal system contributes to the manipulation of goal-directed actions. We studied a group of ten patients with Parkinson's disease (PD) in order to investigate which aspects of action knowledge processing are impaired and to define the conditions under which the deficits may occur. PD patients committed errors of sequence and inserted distractors in tasks that required them to order pre-determined events belonging to a given script in a typical sequence. Rather than attributing errors of event sequencing to a deficit of script "syntax" knowledge, we suggest that the difficulties manifested by PD patients were due to an impairment of a switching mechanism that is necessary for processing information in parallel.</AbstractText>
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Deficit in evaluating pre-determined sequences of script events in patients with Parkinson's disease.

Deficit in evaluating pre-determined sequences of script events in patients with Parkinson's disease.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki