Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications
Identifieur interne : 000312 ( Main/Exploration ); précédent : 000311; suivant : 000313Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications
Auteurs : Julien Perchoux ; Adam Quotb ; Reza Atashkhooei ; Francisco J. Azcona ; Evelio E. Ramírez-Miquet [Cuba] ; Olivier Bernal ; Ajit Jha ; Antonio Luna-Arriaga ; Carlos Yanez ; Jesus Caum ; Thierry Bosch ; Santiago RoyoSource :
- Sensors (Basel, Switzerland) [ 1424-8220 ] ; 2016.
English descriptors
Abstract
Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both
Url:
DOI: 10.3390/s16050694
PubMed: 27187406
PubMed Central: 4883385
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications</title><author><name sortKey="Perchoux, Julien" sort="Perchoux, Julien" uniqKey="Perchoux J" first="Julien" last="Perchoux">Julien Perchoux</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Quotb, Adam" sort="Quotb, Adam" uniqKey="Quotb A" first="Adam" last="Quotb">Adam Quotb</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Atashkhooei, Reza" sort="Atashkhooei, Reza" uniqKey="Atashkhooei R" first="Reza" last="Atashkhooei">Reza Atashkhooei</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Azcona, Francisco J" sort="Azcona, Francisco J" uniqKey="Azcona F" first="Francisco J." last="Azcona">Francisco J. Azcona</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Ramirez Miquet, Evelio E" sort="Ramirez Miquet, Evelio E" uniqKey="Ramirez Miquet E" first="Evelio E." last="Ramírez-Miquet">Evelio E. Ramírez-Miquet</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af3-sensors-16-00694">Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, Calle 30, No. 502, Miramar, La Habana 11300, Cuba</nlm:aff><country xml:lang="fr">Cuba</country><wicri:regionArea>Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, Calle 30, No. 502, Miramar, La Habana 11300</wicri:regionArea><wicri:noRegion>La Habana 11300</wicri:noRegion></affiliation></author><author><name sortKey="Bernal, Olivier" sort="Bernal, Olivier" uniqKey="Bernal O" first="Olivier" last="Bernal">Olivier Bernal</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Jha, Ajit" sort="Jha, Ajit" uniqKey="Jha A" first="Ajit" last="Jha">Ajit Jha</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Luna Arriaga, Antonio" sort="Luna Arriaga, Antonio" uniqKey="Luna Arriaga A" first="Antonio" last="Luna-Arriaga">Antonio Luna-Arriaga</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Yanez, Carlos" sort="Yanez, Carlos" uniqKey="Yanez C" first="Carlos" last="Yanez">Carlos Yanez</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Caum, Jesus" sort="Caum, Jesus" uniqKey="Caum J" first="Jesus" last="Caum">Jesus Caum</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Bosch, Thierry" sort="Bosch, Thierry" uniqKey="Bosch T" first="Thierry" last="Bosch">Thierry Bosch</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Royo, Santiago" sort="Royo, Santiago" uniqKey="Royo S" first="Santiago" last="Royo">Santiago Royo</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> 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(T.B.)</nlm:aff></affiliation></author><author><name sortKey="Quotb, Adam" sort="Quotb, Adam" uniqKey="Quotb A" first="Adam" last="Quotb">Adam Quotb</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Atashkhooei, Reza" sort="Atashkhooei, Reza" uniqKey="Atashkhooei R" first="Reza" last="Atashkhooei">Reza Atashkhooei</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Azcona, Francisco J" sort="Azcona, Francisco J" uniqKey="Azcona F" first="Francisco J." last="Azcona">Francisco J. Azcona</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Ramirez Miquet, Evelio E" sort="Ramirez Miquet, Evelio E" uniqKey="Ramirez Miquet E" first="Evelio E." last="Ramírez-Miquet">Evelio E. Ramírez-Miquet</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af3-sensors-16-00694">Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, Calle 30, No. 502, Miramar, La Habana 11300, Cuba</nlm:aff><country xml:lang="fr">Cuba</country><wicri:regionArea>Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, Calle 30, No. 502, Miramar, La Habana 11300</wicri:regionArea><wicri:noRegion>La Habana 11300</wicri:noRegion></affiliation></author><author><name sortKey="Bernal, Olivier" sort="Bernal, Olivier" uniqKey="Bernal O" first="Olivier" last="Bernal">Olivier Bernal</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Jha, Ajit" sort="Jha, Ajit" uniqKey="Jha A" first="Ajit" last="Jha">Ajit Jha</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Luna Arriaga, Antonio" sort="Luna Arriaga, Antonio" uniqKey="Luna Arriaga A" first="Antonio" last="Luna-Arriaga">Antonio Luna-Arriaga</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Yanez, Carlos" sort="Yanez, Carlos" uniqKey="Yanez C" first="Carlos" last="Yanez">Carlos Yanez</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Caum, Jesus" sort="Caum, Jesus" uniqKey="Caum J" first="Jesus" last="Caum">Jesus Caum</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Bosch, Thierry" sort="Bosch, Thierry" uniqKey="Bosch T" first="Thierry" last="Bosch">Thierry Bosch</name><affiliation><nlm:aff id="af1-sensors-16-00694">LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 Allée Emile Monso, 31400 Toulouse, France;<email>julien.perchoux@enseeiht.fr</email> (J.P.);<email>adam.quotb@enseeiht.fr</email> (A.Q.);<email>ermiquet@ceaden.edu.cu</email> (E.E.R.-M.);<email>olivier.bernal@enseeiht.fr</email> (O.B.);<email>antonio.lunaarriaga@enseeiht.fr</email> (A.L.-A.);<email>thierry.bosch@enseeiht.fr</email> (T.B.)</nlm:aff></affiliation></author><author><name sortKey="Royo, Santiago" sort="Royo, Santiago" uniqKey="Royo S" first="Santiago" last="Royo">Santiago Royo</name><affiliation><nlm:aff id="af2-sensors-16-00694">Centre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, Spain;<email>reza.atashkhooei@cd6.upc.edu</email> (R.A.);<email>francisco.javier.azcona@cd6.upc.edu</email> (F.J.A.);<email>ajit.jha@cd6.upc.edu</email> (A.J.);<email>carlos.yanez@cd6.upc.edu</email> (C.Y.);<email>caum@oo.upc.edu</email> (J.C.)</nlm:aff></affiliation></author></analytic><series><title level="j">Sensors (Basel, Switzerland)</title><idno type="eISSN">1424-8220</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>biophotonics</term><term>biosensors</term><term>flowmetry</term><term>metrology</term><term>optical feedback interferometry</term><term>vibrometry</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both <italic>in vivo</italic> and <italic>ex vivo</italic>. This work is intended to present the variety of opportunities and potential applications related to OFI that are available in the field. The activities presented are divided into two main sensing strategies: The measurement of optical path changes and the monitoring of flows, which correspond to sensing strategies linked to the reconstruction of changes of amplitude from the interferometric signal, and to classical Doppler frequency measurements, respectively. For optical path change measurements, measurements of transient pulses, usual in biosensing, together with the measurement of large displacements applied to designing palliative care instrumentation for Parkinson disease are discussed. Regarding the Doppler-based approach, progress in flow-related signal processing and applications in real-time monitoring of non-steady flows, human blood flow monitoring and OFI pressure myograph sensing will be presented. In all cases, experimental setups are discussed and results presented, showing the versatility of the technique. The described applications show the wide capabilities in biosensing of the OFI sensor, showing it as an enabler of low-cost, all-optical, high accuracy biomedical applications.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kane, D M" uniqKey="Kane D">D.M. Kane</name></author><author><name sortKey="Shore, K A" uniqKey="Shore K">K.A. Shore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taimre, T" uniqKey="Taimre T">T. Taimre</name></author><author><name sortKey="Nikoli, M" uniqKey="Nikoli M">M. 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Wilkes</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Cuba</li></country></list><tree><noCountry><name sortKey="Atashkhooei, Reza" sort="Atashkhooei, Reza" uniqKey="Atashkhooei R" first="Reza" last="Atashkhooei">Reza Atashkhooei</name><name sortKey="Azcona, Francisco J" sort="Azcona, Francisco J" uniqKey="Azcona F" first="Francisco J." last="Azcona">Francisco J. Azcona</name><name sortKey="Bernal, Olivier" sort="Bernal, Olivier" uniqKey="Bernal O" first="Olivier" last="Bernal">Olivier Bernal</name><name sortKey="Bosch, Thierry" sort="Bosch, Thierry" uniqKey="Bosch T" first="Thierry" last="Bosch">Thierry Bosch</name><name sortKey="Caum, Jesus" sort="Caum, Jesus" uniqKey="Caum J" first="Jesus" last="Caum">Jesus Caum</name><name sortKey="Jha, Ajit" sort="Jha, Ajit" uniqKey="Jha A" first="Ajit" last="Jha">Ajit Jha</name><name sortKey="Luna Arriaga, Antonio" sort="Luna Arriaga, Antonio" uniqKey="Luna Arriaga A" first="Antonio" last="Luna-Arriaga">Antonio Luna-Arriaga</name><name sortKey="Perchoux, Julien" sort="Perchoux, Julien" uniqKey="Perchoux J" first="Julien" last="Perchoux">Julien Perchoux</name><name sortKey="Quotb, Adam" sort="Quotb, Adam" uniqKey="Quotb A" first="Adam" last="Quotb">Adam Quotb</name><name sortKey="Royo, Santiago" sort="Royo, Santiago" uniqKey="Royo S" first="Santiago" last="Royo">Santiago Royo</name><name sortKey="Yanez, Carlos" sort="Yanez, Carlos" uniqKey="Yanez C" first="Carlos" last="Yanez">Carlos Yanez</name></noCountry><country name="Cuba"><noRegion><name sortKey="Ramirez Miquet, Evelio E" sort="Ramirez Miquet, Evelio E" uniqKey="Ramirez Miquet E" first="Evelio E." last="Ramírez-Miquet">Evelio E. 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