PandemieGrippaleV1, Main, Merge, bibRecord, 004F13

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

Identifieur interne : 004F13 ( Main/Merge ); précédent : 004F12; suivant : 004F14

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

Auteurs : Rafi Ahmed [États-Unis] ; Michael B A. Oldstone [États-Unis] ; Peter Palese [États-Unis]

Source :

Nature Immunology [ 1529-2908 ] ; 2007-11.

RBID : ISTEX:348DD5371524339254650108045A66E0BB9C8A83

Descripteurs français

KwdFr :
- Adolescent, Adulte, Enfant, Facteurs de l'âge, Flambées de maladies (histoire), Grippe humaine (immunologie), Grippe humaine (mortalité), Histoire du 20ème siècle, Humains, Mémoire immunologique, Susceptibilité à une maladie (immunologie).
MESH :
- histoire : Flambées de maladies.
- immunologie : Grippe humaine, Susceptibilité à une maladie.
- mortalité : Grippe humaine.
- Adolescent, Adulte, Enfant, Facteurs de l'âge, Histoire du 20ème siècle, Humains, Mémoire immunologique.

English descriptors

KwdEn :
- Adolescent, Adult, Age Factors, Child, Disease Outbreaks (history), Disease Susceptibility (immunology), History, 20th Century, Humans, Immunologic Memory, Influenza, Human (immunology), Influenza, Human (mortality).
MESH :
- history : Disease Outbreaks.
- immunology : Disease Susceptibility, Influenza, Human.
- mortality : Influenza, Human.
- Adolescent, Adult, Age Factors, Child, History, 20th Century, Humans, Immunologic Memory.

Abstract

The influenza pandemic of 1918 killed nearly 50 million people worldwide and was characterized by an atypical W-shaped mortality curve, where adults between the ages of 30–60 years fared better than younger adults aged 18–30 years. In this review, we will discuss why this influenza virus strain was so virulent and how immunological memory to the 1918 virus may have shaped the W mortality curve. We will end on the topic of the 'honeymoon' period of infectious diseases—the clinically documented period between the ages of 4–13 years during which children demonstrate less morbidity and/or mortality to infectious diseases, in general, compared with young adults.

Url:

DOI: 10.1038/ni1530

Links to Exploration step

ISTEX:348DD5371524339254650108045A66E0BB9C8A83

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:348DD5371524339254650108045A66E0BB9C8A83</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1038/ni1530</idno>
<idno type="url">https://api.istex.fr/ark:/67375/GT4-QK5C7LBP-K/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000307</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000307</idno>
<idno type="wicri:Area/Istex/Curation">000307</idno>
<idno type="wicri:Area/Istex/Checkpoint">001513</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001513</idno>
<idno type="wicri:doubleKey">1529-2908:2007:Ahmed R:protective:immunity:and</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097533</idno>
<idno type="RBID">PMC:7097533</idno>
<idno type="wicri:Area/Pmc/Corpus">000299</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000299</idno>
<idno type="wicri:Area/Pmc/Curation">000299</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000299</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000D59</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000D59</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17952044</idno>
<idno type="wicri:Area/PubMed/Corpus">001A66</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A66</idno>
<idno type="wicri:Area/PubMed/Curation">001A66</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001A66</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001912</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001912</idno>
<idno type="wicri:Area/Ncbi/Merge">000593</idno>
<idno type="wicri:Area/Ncbi/Curation">000593</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000593</idno>
<idno type="wicri:doubleKey">1529-2908:2007:Ahmed R:protective:immunity:and</idno>
<idno type="wicri:Area/Main/Merge">004F13</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322</wicri:regionArea>
<wicri:noRegion>Georgia 30322</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Viral-Immunobiology Laboratory, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037</wicri:regionArea>
<wicri:noRegion>California 92037</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Departments of Microbiology and Medicine, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, New York 10029</wicri:regionArea>
<wicri:noRegion>New York 10029</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Nature Immunology</title>
<idno type="ISSN">1529-2908</idno>
<imprint><publisher>Nature Publishing Group</publisher>
<date when="2007-11">2007-11</date>
<biblScope unit="vol">8</biblScope>
<biblScope unit="issue">11</biblScope>
<biblScope unit="page" from="1188">1188</biblScope>
<biblScope unit="page" to="1193">1193</biblScope>
<date type="Copyright" when="2007">2007</date>
</imprint>
<idno type="ISSN">1529-2908</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1529-2908</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Factors</term>
<term>Child</term>
<term>Disease Outbreaks (history)</term>
<term>Disease Susceptibility (immunology)</term>
<term>History, 20th Century</term>
<term>Humans</term>
<term>Immunologic Memory</term>
<term>Influenza, Human (immunology)</term>
<term>Influenza, Human (mortality)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Enfant</term>
<term>Facteurs de l'âge</term>
<term>Flambées de maladies (histoire)</term>
<term>Grippe humaine (immunologie)</term>
<term>Grippe humaine (mortalité)</term>
<term>Histoire du 20ème siècle</term>
<term>Humains</term>
<term>Mémoire immunologique</term>
<term>Susceptibilité à une maladie (immunologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="histoire" xml:lang="fr"><term>Flambées de maladies</term>
</keywords>
<keywords scheme="MESH" qualifier="history" xml:lang="en"><term>Disease Outbreaks</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term>
<term>Susceptibilité à une maladie</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Disease Susceptibility</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Factors</term>
<term>Child</term>
<term>History, 20th Century</term>
<term>Humans</term>
<term>Immunologic Memory</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Enfant</term>
<term>Facteurs de l'âge</term>
<term>Histoire du 20ème siècle</term>
<term>Humains</term>
<term>Mémoire immunologique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="eng">The influenza pandemic of 1918 killed nearly 50 million people worldwide and was characterized by an atypical W-shaped mortality curve, where adults between the ages of 30–60 years fared better than younger adults aged 18–30 years. In this review, we will discuss why this influenza virus strain was so virulent and how immunological memory to the 1918 virus may have shaped the W mortality curve. We will end on the topic of the 'honeymoon' period of infectious diseases—the clinically documented period between the ages of 4–13 years during which children demonstrate less morbidity and/or mortality to infectious diseases, in general, compared with young adults.</div>
</front>
</TEI>
<double doi="10.1038/ni1530"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:348DD5371524339254650108045A66E0BB9C8A83</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1038/ni1530</idno>
<idno type="url">https://api.istex.fr/ark:/67375/GT4-QK5C7LBP-K/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000307</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000307</idno>
<idno type="wicri:Area/Istex/Curation">000307</idno>
<idno type="wicri:Area/Istex/Checkpoint">001513</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001513</idno>
<idno type="wicri:doubleKey">1529-2908:2007:Ahmed R:protective:immunity:and</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322</wicri:regionArea>
<wicri:noRegion>Georgia 30322</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Viral-Immunobiology Laboratory, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037</wicri:regionArea>
<wicri:noRegion>California 92037</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Departments of Microbiology and Medicine, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, New York 10029</wicri:regionArea>
<wicri:noRegion>New York 10029</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Nature Immunology</title>
<idno type="ISSN">1529-2908</idno>
<imprint><publisher>Nature Publishing Group</publisher>
<date when="2007-11">2007-11</date>
<biblScope unit="vol">8</biblScope>
<biblScope unit="issue">11</biblScope>
<biblScope unit="page" from="1188">1188</biblScope>
<biblScope unit="page" to="1193">1193</biblScope>
<date type="Copyright" when="2007">2007</date>
</imprint>
<idno type="ISSN">1529-2908</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1529-2908</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="eng">The influenza pandemic of 1918 killed nearly 50 million people worldwide and was characterized by an atypical W-shaped mortality curve, where adults between the ages of 30–60 years fared better than younger adults aged 18–30 years. In this review, we will discuss why this influenza virus strain was so virulent and how immunological memory to the 1918 virus may have shaped the W mortality curve. We will end on the topic of the 'honeymoon' period of infectious diseases—the clinically documented period between the ages of 4–13 years during which children demonstrate less morbidity and/or mortality to infectious diseases, in general, compared with young adults.</div>
</front>
</TEI>
</ISTEX>
<PMC><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
<affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.189967.8</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 0941 6502</institution-id>
<institution>Emory Vaccine Center and Department of Microbiology and Immunology,</institution>
<institution>Emory University School of Medicine,</institution>
</institution-wrap>
Atlanta, 30322 Georgia USA</nlm:aff>
<wicri:noCountry code="subfield">30322 Georgia USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.214007.0</institution-id>
<institution-id institution-id-type="ISNI">0000000122199231</institution-id>
<institution>Molecular and Integrative Neurosciences Department,</institution>
<institution>Viral-Immunobiology Laboratory, The Scripps Research Institute,</institution>
</institution-wrap>
10550 N. Torrey Pines Road, La Jolla, 92037 California USA</nlm:aff>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:regionArea>10550 N. Torrey Pines Road, La Jolla</wicri:regionArea>
<wicri:noRegion>La Jolla</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
<affiliation wicri:level="2"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="GRID">grid.59734.3c</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 0670 2351</institution-id>
<institution>Departments of Microbiology and Medicine,</institution>
<institution>Mount Sinai School of Medicine,</institution>
</institution-wrap>
1 Gustave L. Levy Place, New York, 10029 New York USA</nlm:aff>
<country>États-Unis</country>
<placeName><settlement type="city">New York</settlement>
<region type="state">État de New York</region>
</placeName>
<wicri:regionArea>1 Gustave L. Levy Place, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">17952044</idno>
<idno type="pmc">7097533</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097533</idno>
<idno type="RBID">PMC:7097533</idno>
<idno type="doi">10.1038/ni1530</idno>
<date when="2007">2007</date>
<idno type="wicri:Area/Pmc/Corpus">000299</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000299</idno>
<idno type="wicri:Area/Pmc/Curation">000299</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000299</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000D59</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000D59</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17952044</idno>
<idno type="wicri:Area/PubMed/Corpus">001A66</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A66</idno>
<idno type="wicri:Area/PubMed/Curation">001A66</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001A66</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001912</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001912</idno>
<idno type="wicri:Area/Ncbi/Merge">000593</idno>
<idno type="wicri:Area/Ncbi/Curation">000593</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000593</idno>
<idno type="wicri:doubleKey">1529-2908:2007:Ahmed R:protective:immunity:and</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic</title>
<author><name sortKey="Ahmed, Rafi" sort="Ahmed, Rafi" uniqKey="Ahmed R" first="Rafi" last="Ahmed">Rafi Ahmed</name>
<affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.189967.8</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 0941 6502</institution-id>
<institution>Emory Vaccine Center and Department of Microbiology and Immunology,</institution>
<institution>Emory University School of Medicine,</institution>
</institution-wrap>
Atlanta, 30322 Georgia USA</nlm:aff>
<wicri:noCountry code="subfield">30322 Georgia USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Oldstone, Michael B A" sort="Oldstone, Michael B A" uniqKey="Oldstone M" first="Michael B A" last="Oldstone">Michael B A. Oldstone</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.214007.0</institution-id>
<institution-id institution-id-type="ISNI">0000000122199231</institution-id>
<institution>Molecular and Integrative Neurosciences Department,</institution>
<institution>Viral-Immunobiology Laboratory, The Scripps Research Institute,</institution>
</institution-wrap>
10550 N. Torrey Pines Road, La Jolla, 92037 California USA</nlm:aff>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:regionArea>10550 N. Torrey Pines Road, La Jolla</wicri:regionArea>
<wicri:noRegion>La Jolla</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Palese, Peter" sort="Palese, Peter" uniqKey="Palese P" first="Peter" last="Palese">Peter Palese</name>
<affiliation wicri:level="2"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="GRID">grid.59734.3c</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 0670 2351</institution-id>
<institution>Departments of Microbiology and Medicine,</institution>
<institution>Mount Sinai School of Medicine,</institution>
</institution-wrap>
1 Gustave L. Levy Place, New York, 10029 New York USA</nlm:aff>
<country>États-Unis</country>
<placeName><settlement type="city">New York</settlement>
<region type="state">État de New York</region>
</placeName>
<wicri:regionArea>1 Gustave L. Levy Place, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature Immunology</title>
<idno type="ISSN">1529-2908</idno>
<idno type="eISSN">1529-2916</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Factors</term>
<term>Child</term>
<term>Disease Outbreaks (history)</term>
<term>Disease Susceptibility (immunology)</term>
<term>History, 20th Century</term>
<term>Humans</term>
<term>Immunologic Memory</term>
<term>Influenza, Human (immunology)</term>
<term>Influenza, Human (mortality)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Enfant</term>
<term>Facteurs de l'âge</term>
<term>Flambées de maladies (histoire)</term>
<term>Grippe humaine (immunologie)</term>
<term>Grippe humaine (mortalité)</term>
<term>Histoire du 20ème siècle</term>
<term>Humains</term>
<term>Mémoire immunologique</term>
<term>Susceptibilité à une maladie (immunologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="histoire" xml:lang="fr"><term>Flambées de maladies</term>
</keywords>
<keywords scheme="MESH" qualifier="history" xml:lang="en"><term>Disease Outbreaks</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term>
<term>Susceptibilité à une maladie</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Disease Susceptibility</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Factors</term>
<term>Child</term>
<term>History, 20th Century</term>
<term>Humans</term>
<term>Immunologic Memory</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Enfant</term>
<term>Facteurs de l'âge</term>
<term>Histoire du 20ème siècle</term>
<term>Humains</term>
<term>Mémoire immunologique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="Par1">The influenza pandemic of 1918 killed nearly 50 million people worldwide and was characterized by an atypical W-shaped mortality curve, where adults between the ages of 30–60 years fared better than younger adults aged 18–30 years. In this review, we will discuss why this influenza virus strain was so virulent and how immunological memory to the 1918 virus may have shaped the W mortality curve. We will end on the topic of the 'honeymoon' period of infectious diseases—the clinically documented period between the ages of 4–13 years during which children demonstrate less morbidity and/or mortality to infectious diseases, in general, compared with young adults.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Johnson, Np" uniqKey="Johnson N">NP Johnson</name>
</author>
<author><name sortKey="Mueller, J" uniqKey="Mueller J">J Mueller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Palese, P" uniqKey="Palese P">P Palese</name>
</author>
<author><name sortKey="Shaw, Ml" uniqKey="Shaw M">ML Shaw</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kobasa, D" uniqKey="Kobasa D">D Kobasa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kash, Jc" uniqKey="Kash J">JC Kash</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dowdle, Wr" uniqKey="Dowdle W">WR Dowdle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Crosby, Aw" uniqKey="Crosby A">AW Crosby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Langford, C" uniqKey="Langford C">C Langford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Palese, P" uniqKey="Palese P">P Palese</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Palese, P" uniqKey="Palese P">P Palese</name>
</author>
<author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
<author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A Garcia-Sastre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Doherty, Pc" uniqKey="Doherty P">PC Doherty</name>
</author>
<author><name sortKey="Turner, Sj" uniqKey="Turner S">SJ Turner</name>
</author>
<author><name sortKey="Webby, Rg" uniqKey="Webby R">RG Webby</name>
</author>
<author><name sortKey="Thomas, Pg" uniqKey="Thomas P">PG Thomas</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Horimoto, T" uniqKey="Horimoto T">T Horimoto</name>
</author>
<author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y Kawaoka</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sandbulte, Mr" uniqKey="Sandbulte M">MR Sandbulte</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Amanna, Ij" uniqKey="Amanna I">IJ Amanna</name>
</author>
<author><name sortKey="Slifka, Mk" uniqKey="Slifka M">MK Slifka</name>
</author>
<author><name sortKey="Crotty, S" uniqKey="Crotty S">S Crotty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bernasconi, Nl" uniqKey="Bernasconi N">NL Bernasconi</name>
</author>
<author><name sortKey="Traggiai, E" uniqKey="Traggiai E">E Traggiai</name>
</author>
<author><name sortKey="Lanzavecchia, A" uniqKey="Lanzavecchia A">A Lanzavecchia</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Plotkin, Sa" uniqKey="Plotkin S">SA Plotkin</name>
</author>
<author><name sortKey="Orenstein, Wa" uniqKey="Orenstein W">WA Orenstein</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Crotty, S" uniqKey="Crotty S">S Crotty</name>
</author>
<author><name sortKey="Kersh, En" uniqKey="Kersh E">EN Kersh</name>
</author>
<author><name sortKey="Cannons, J" uniqKey="Cannons J">J Cannons</name>
</author>
<author><name sortKey="Schwartzberg, Pl" uniqKey="Schwartzberg P">PL Schwartzberg</name>
</author>
<author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Manz, Ra" uniqKey="Manz R">RA Manz</name>
</author>
<author><name sortKey="Thiel, A" uniqKey="Thiel A">A Thiel</name>
</author>
<author><name sortKey="Radbruch, A" uniqKey="Radbruch A">A Radbruch</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Slifka, Mk" uniqKey="Slifka M">MK Slifka</name>
</author>
<author><name sortKey="Antia, R" uniqKey="Antia R">R Antia</name>
</author>
<author><name sortKey="Whitmire, Jk" uniqKey="Whitmire J">JK Whitmire</name>
</author>
<author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kalia, V" uniqKey="Kalia V">V Kalia</name>
</author>
<author><name sortKey="Sarkar, S" uniqKey="Sarkar S">S Sarkar</name>
</author>
<author><name sortKey="Gourley, Ts" uniqKey="Gourley T">TS Gourley</name>
</author>
<author><name sortKey="Rouse, Bt" uniqKey="Rouse B">BT Rouse</name>
</author>
<author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Crotty, S" uniqKey="Crotty S">S Crotty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hammarlund, E" uniqKey="Hammarlund E">E Hammarlund</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
<author><name sortKey="Rouse, Bt" uniqKey="Rouse B">BT Rouse</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hikono, H" uniqKey="Hikono H">H Hikono</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcmichael, Aj" uniqKey="Mcmichael A">AJ McMichael</name>
</author>
<author><name sortKey="Gotch, Fm" uniqKey="Gotch F">FM Gotch</name>
</author>
<author><name sortKey="Noble, Gr" uniqKey="Noble G">GR Noble</name>
</author>
<author><name sortKey="Beare, Pa" uniqKey="Beare P">PA Beare</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Swain, Sl" uniqKey="Swain S">SL Swain</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Feigin, Rd" uniqKey="Feigin R">RD Feigin</name>
</author>
<author><name sortKey="Cherry, J" uniqKey="Cherry J">J Cherry</name>
</author>
<author><name sortKey="Demmler, Gj" uniqKey="Demmler G">GJ Demmler</name>
</author>
<author><name sortKey="Kaplan, S" uniqKey="Kaplan S">S Kaplan</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Stadler, K" uniqKey="Stadler K">K Stadler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Finlay, Bb" uniqKey="Finlay B">BB Finlay</name>
</author>
<author><name sortKey="See, Rh" uniqKey="See R">RH See</name>
</author>
<author><name sortKey="Brunham, Rc" uniqKey="Brunham R">RC Brunham</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zinkernagel, Rm" uniqKey="Zinkernagel R">RM Zinkernagel</name>
</author>
<author><name sortKey="Hengartner, H" uniqKey="Hengartner H">H Hengartner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oldstone, Mb" uniqKey="Oldstone M">MB Oldstone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brooks, Dg" uniqKey="Brooks D">DG Brooks</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ejrnaes, M" uniqKey="Ejrnaes M">M Ejrnaes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liston, A" uniqKey="Liston A">A Liston</name>
</author>
<author><name sortKey="Rudensky, Ay" uniqKey="Rudensky A">AY Rudensky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shevach, Em" uniqKey="Shevach E">EM Shevach</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miyara, M" uniqKey="Miyara M">M Miyara</name>
</author>
<author><name sortKey="Sakaguchi, S" uniqKey="Sakaguchi S">S Sakaguchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bettelli, E" uniqKey="Bettelli E">E Bettelli</name>
</author>
<author><name sortKey="Oukka, M" uniqKey="Oukka M">M Oukka</name>
</author>
<author><name sortKey="Kuchroo, Vkt" uniqKey="Kuchroo V">VKT Kuchroo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barber, Dl" uniqKey="Barber D">DL Barber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sharpe, Ah" uniqKey="Sharpe A">AH Sharpe</name>
</author>
<author><name sortKey="Wherry, Ej" uniqKey="Wherry E">EJ Wherry</name>
</author>
<author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
<author><name sortKey="Freeman, Gj" uniqKey="Freeman G">GJ Freeman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roberts, Cw" uniqKey="Roberts C">CW Roberts</name>
</author>
<author><name sortKey="Walker, W" uniqKey="Walker W">W Walker</name>
</author>
<author><name sortKey="Alexander, J" uniqKey="Alexander J">J Alexander</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A Garcia-Sastre</name>
</author>
<author><name sortKey="Biron, Ca" uniqKey="Biron C">CA Biron</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kolumam, Ga" uniqKey="Kolumam G">GA Kolumam</name>
</author>
<author><name sortKey="Thomas, S" uniqKey="Thomas S">S Thomas</name>
</author>
<author><name sortKey="Thompson, Lj" uniqKey="Thompson L">LJ Thompson</name>
</author>
<author><name sortKey="Sprent, J" uniqKey="Sprent J">J Sprent</name>
</author>
<author><name sortKey="Murali Krishna, K" uniqKey="Murali Krishna K">K Murali-Krishna</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Duin, D" uniqKey="Van Duin D">D van Duin</name>
</author>
<author><name sortKey="Medzhitov, R" uniqKey="Medzhitov R">R Medzhitov</name>
</author>
<author><name sortKey="Shaw, Ac" uniqKey="Shaw A">AC Shaw</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pulendran, B" uniqKey="Pulendran B">B Pulendran</name>
</author>
<author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Reisinger, Ks" uniqKey="Reisinger K">KS Reisinger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Giuliarno, Ar" uniqKey="Giuliarno A">AR Giuliarno</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</PMC>
</double>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004F13 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 004F13 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    Main
   |étape=   Merge
   |type=    RBID
   |clé=     ISTEX:348DD5371524339254650108045A66E0BB9C8A83
   |texte=   Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic
}}

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021

Serveur d'exploration sur les pandémies grippales

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur les pandémies grippales
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.