Gender differences in the association between antidepressant use and restless legs syndrome
Identifieur interne : 002292 ( Main/Exploration ); précédent : 002291; suivant : 002293Gender differences in the association between antidepressant use and restless legs syndrome
Auteurs : Kristin R. Baughman [États-Unis] ; Claire C. Bourguet [États-Unis] ; Scott K. Ober [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-05-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Antidepressive Agents (adverse effects), Antidepressive Agents (classification), Depression, Female, Humans, Male, Middle Aged, Nervous system diseases, Observation, Primary Health Care (statistics & numerical data), Regression Analysis, Restless Legs Syndrome (chemically induced), Restless legs syndrome, Risk Factors, Sex, Sex Characteristics, Veterans, Young Adult, antidepressants, depression, gender, restless legs syndrome.
- MESH :
- chemical , adverse effects : Antidepressive Agents.
- chemical , classification : Antidepressive Agents.
- chemically induced : Restless Legs Syndrome.
- statistics & numerical data : Primary Health Care.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Observation, Regression Analysis, Risk Factors, Sex Characteristics, Veterans, Young Adult.
Abstract
Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary care from the Cleveland VA Medical Center and obtained prescription drug information from their medical records. Overall, use of an antidepressant was associated with RLS for men (RR = 1.77, CI = 1.26, 2.48) but not for women (RR = 0.79, CI = 0.43, 1.47). Analyses of individual antidepressants revealed an association between RLS and fluoxetine for women (RR = 2.47, CI = 1.33, 4.56), and associations between RLS and citalopram, (RR = 2.09, CI = 1.20, 3.64), paroxetine (RR = 1.97, CI = 1.02, 3.79), and amitriptyline (RR = 2.40, CI = 1.45, 4.00) for men. We conclude that RLS may be associated with antidepressant use, but the association varies by gender and type of antidepressant. Antidepressant use is more strongly associated with RLS in men than in women. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22517
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001C91
- to stream Istex, to step Curation: 001C91
- to stream Istex, to step Checkpoint: 000E94
- to stream PubMed, to step Corpus: 001D68
- to stream PubMed, to step Curation: 001D68
- to stream PubMed, to step Checkpoint: 001D97
- to stream Ncbi, to step Merge: 002609
- to stream Ncbi, to step Curation: 002609
- to stream Ncbi, to step Checkpoint: 002609
- to stream Main, to step Merge: 002B53
- to stream PascalFrancis, to step Corpus: 000E78
- to stream PascalFrancis, to step Curation: 001E41
- to stream PascalFrancis, to step Checkpoint: 000E65
- to stream Main, to step Merge: 002F62
- to stream Main, to step Curation: 002292
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Gender differences in the association between antidepressant use and restless legs syndrome</title><author><name sortKey="Baughman, Kristin R" sort="Baughman, Kristin R" uniqKey="Baughman K" first="Kristin R." last="Baughman">Kristin R. Baughman</name></author><author><name sortKey="Bourguet, Claire C" sort="Bourguet, Claire C" uniqKey="Bourguet C" first="Claire C." last="Bourguet">Claire C. Bourguet</name></author><author><name sortKey="Ober, Scott K" sort="Ober, Scott K" uniqKey="Ober S" first="Scott K." last="Ober">Scott K. Ober</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:34E446D5DDE5F80F5A0B7446A1023D35831190E5</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22517</idno><idno type="url">https://api.istex.fr/document/34E446D5DDE5F80F5A0B7446A1023D35831190E5/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001C91</idno><idno type="wicri:Area/Istex/Curation">001C91</idno><idno type="wicri:Area/Istex/Checkpoint">000E94</idno><idno type="wicri:doubleKey">0885-3185:2009:Baughman K:gender:differences:in</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:19353713</idno><idno type="wicri:Area/PubMed/Corpus">001D68</idno><idno type="wicri:Area/PubMed/Curation">001D68</idno><idno type="wicri:Area/PubMed/Checkpoint">001D97</idno><idno type="wicri:Area/Ncbi/Merge">002609</idno><idno type="wicri:Area/Ncbi/Curation">002609</idno><idno type="wicri:Area/Ncbi/Checkpoint">002609</idno><idno type="wicri:Area/Main/Merge">002B53</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:09-0257328</idno><idno type="wicri:Area/PascalFrancis/Corpus">000E78</idno><idno type="wicri:Area/PascalFrancis/Curation">001E41</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000E65</idno><idno type="wicri:doubleKey">0885-3185:2009:Baughman K:gender:differences:in</idno><idno type="wicri:Area/Main/Merge">002F62</idno><idno type="wicri:Area/Main/Curation">002292</idno><idno type="wicri:Area/Main/Exploration">002292</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Gender differences in the association between antidepressant use and restless legs syndrome</title><author><name sortKey="Baughman, Kristin R" sort="Baughman, Kristin R" uniqKey="Baughman K" first="Kristin R." last="Baughman">Kristin R. Baughman</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Behavioral and Community Health Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Bourguet, Claire C" sort="Bourguet, Claire C" uniqKey="Bourguet C" first="Claire C." last="Bourguet">Claire C. Bourguet</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Behavioral and Community Health Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Ober, Scott K" sort="Ober, Scott K" uniqKey="Ober S" first="Scott K." last="Ober">Scott K. Ober</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Community Outpatient Services, Louis B. Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-05-15">2009-05-15</date><biblScope unit="vol">24</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1054">1054</biblScope><biblScope unit="page" to="1059">1059</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">34E446D5DDE5F80F5A0B7446A1023D35831190E5</idno><idno type="DOI">10.1002/mds.22517</idno><idno type="ArticleID">MDS22517</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Antidepressive Agents (adverse effects)</term><term>Antidepressive Agents (classification)</term><term>Depression</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Observation</term><term>Primary Health Care (statistics & numerical data)</term><term>Regression Analysis</term><term>Restless Legs Syndrome (chemically induced)</term><term>Restless legs syndrome</term><term>Risk Factors</term><term>Sex</term><term>Sex Characteristics</term><term>Veterans</term><term>Young Adult</term><term>antidepressants</term><term>depression</term><term>gender</term><term>restless legs syndrome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antidepressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="classification" xml:lang="en"><term>Antidepressive Agents</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Restless Legs Syndrome</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Primary Health Care</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Observation</term><term>Regression Analysis</term><term>Risk Factors</term><term>Sex Characteristics</term><term>Veterans</term><term>Young Adult</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Etat dépressif</term><term>Pathologie du système nerveux</term><term>Sexe</term><term>Syndrome des jambes sans repos</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary care from the Cleveland VA Medical Center and obtained prescription drug information from their medical records. Overall, use of an antidepressant was associated with RLS for men (RR = 1.77, CI = 1.26, 2.48) but not for women (RR = 0.79, CI = 0.43, 1.47). Analyses of individual antidepressants revealed an association between RLS and fluoxetine for women (RR = 2.47, CI = 1.33, 4.56), and associations between RLS and citalopram, (RR = 2.09, CI = 1.20, 3.64), paroxetine (RR = 1.97, CI = 1.02, 3.79), and amitriptyline (RR = 2.40, CI = 1.45, 4.00) for men. We conclude that RLS may be associated with antidepressant use, but the association varies by gender and type of antidepressant. Antidepressant use is more strongly associated with RLS in men than in women. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Ohio</li></region></list><tree><country name="États-Unis"><region name="Ohio"><name sortKey="Baughman, Kristin R" sort="Baughman, Kristin R" uniqKey="Baughman K" first="Kristin R." last="Baughman">Kristin R. Baughman</name></region><name sortKey="Bourguet, Claire C" sort="Bourguet, Claire C" uniqKey="Bourguet C" first="Claire C." last="Bourguet">Claire C. Bourguet</name><name sortKey="Ober, Scott K" sort="Ober, Scott K" uniqKey="Ober S" first="Scott K." last="Ober">Scott K. Ober</name><name sortKey="Ober, Scott K" sort="Ober, Scott K" uniqKey="Ober S" first="Scott K." last="Ober">Scott K. Ober</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002292 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002292 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:34E446D5DDE5F80F5A0B7446A1023D35831190E5
|texte= Gender differences in the association between antidepressant use and restless legs syndrome
}}
| This area was generated with Dilib version V0.6.23. |  |