MovDisordV3, PubMed, Corpus, bibRecord, 001D68

Gender differences in the association between antidepressant use and restless legs syndrome.

Identifieur interne : 001D68 ( PubMed/Corpus ); précédent : 001D67; suivant : 001D69

Gender differences in the association between antidepressant use and restless legs syndrome.

Auteurs : Kristin R. Baughman ; Claire C. Bourguet ; Scott K. Ober

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2009.

RBID : pubmed:19353713

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Antidepressive Agents (adverse effects), Antidepressive Agents (classification), Female, Humans, Male, Middle Aged, Observation, Primary Health Care (statistics & numerical data), Regression Analysis, Restless Legs Syndrome (chemically induced), Risk Factors, Sex Characteristics, Veterans, Young Adult.
MESH :
- chemical , adverse effects : Antidepressive Agents.
- chemical , classification : Antidepressive Agents.
- chemically induced : Restless Legs Syndrome.
- statistics & numerical data : Primary Health Care.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Observation, Regression Analysis, Risk Factors, Sex Characteristics, Veterans, Young Adult.

Abstract

Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary care from the Cleveland VA Medical Center and obtained prescription drug information from their medical records. Overall, use of an antidepressant was associated with RLS for men (RR = 1.77, CI = 1.26, 2.48) but not for women (RR = 0.79, CI = 0.43, 1.47). Analyses of individual antidepressants revealed an association between RLS and fluoxetine for women (RR = 2.47, CI = 1.33, 4.56), and associations between RLS and citalopram, (RR = 2.09, CI = 1.20, 3.64), paroxetine (RR = 1.97, CI = 1.02, 3.79), and amitriptyline (RR = 2.40, CI = 1.45, 4.00) for men. We conclude that RLS may be associated with antidepressant use, but the association varies by gender and type of antidepressant. Antidepressant use is more strongly associated with RLS in men than in women.

DOI: 10.1002/mds.22517
PubMed: 19353713

Links to Exploration step

pubmed:19353713

Le document en format XML

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<author><name sortKey="Baughman, Kristin R" sort="Baughman, Kristin R" uniqKey="Baughman K" first="Kristin R" last="Baughman">Kristin R. Baughman</name>
<affiliation><nlm:affiliation>Department of Behavioral and Community Health Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio 44272, USA. kbaughma@neoucom.edu</nlm:affiliation>
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<author><name sortKey="Bourguet, Claire C" sort="Bourguet, Claire C" uniqKey="Bourguet C" first="Claire C" last="Bourguet">Claire C. Bourguet</name>
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<author><name sortKey="Ober, Scott K" sort="Ober, Scott K" uniqKey="Ober S" first="Scott K" last="Ober">Scott K. Ober</name>
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<term>Antidepressive Agents (classification)</term>
<term>Female</term>
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<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary care from the Cleveland VA Medical Center and obtained prescription drug information from their medical records. Overall, use of an antidepressant was associated with RLS for men (RR = 1.77, CI = 1.26, 2.48) but not for women (RR = 0.79, CI = 0.43, 1.47). Analyses of individual antidepressants revealed an association between RLS and fluoxetine for women (RR = 2.47, CI = 1.33, 4.56), and associations between RLS and citalopram, (RR = 2.09, CI = 1.20, 3.64), paroxetine (RR = 1.97, CI = 1.02, 3.79), and amitriptyline (RR = 2.40, CI = 1.45, 4.00) for men. We conclude that RLS may be associated with antidepressant use, but the association varies by gender and type of antidepressant. Antidepressant use is more strongly associated with RLS in men than in women.</div>
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<Abstract><AbstractText>Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary care from the Cleveland VA Medical Center and obtained prescription drug information from their medical records. Overall, use of an antidepressant was associated with RLS for men (RR = 1.77, CI = 1.26, 2.48) but not for women (RR = 0.79, CI = 0.43, 1.47). Analyses of individual antidepressants revealed an association between RLS and fluoxetine for women (RR = 2.47, CI = 1.33, 4.56), and associations between RLS and citalopram, (RR = 2.09, CI = 1.20, 3.64), paroxetine (RR = 1.97, CI = 1.02, 3.79), and amitriptyline (RR = 2.40, CI = 1.45, 4.00) for men. We conclude that RLS may be associated with antidepressant use, but the association varies by gender and type of antidepressant. Antidepressant use is more strongly associated with RLS in men than in women.</AbstractText>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Gender differences in the association between antidepressant use and restless legs syndrome.

Gender differences in the association between antidepressant use and restless legs syndrome.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki