MovDisordV3, Main, Exploration, bibRecordById, pubmed:18671287

Urinary isoprostanes in Friedreich ataxia: Lack of correlation with disease features

Identifieur interne : 002546 ( Main/Exploration ); précédent : 002545; suivant : 002547

Urinary isoprostanes in Friedreich ataxia: Lack of correlation with disease features

Auteurs : Lauren M. Myers [États-Unis] ; David R. Lynch [États-Unis] ; Jennifer M. Farmer [États-Unis] ; Lisa S. Friedman [États-Unis] ; John A. Lawson [États-Unis] ; Robert B. Wilson [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2008-10-15.

RBID : ISTEX:B9848DC061D01E81BC49CAFF39D2976CBC0FF5A3

Descripteurs français

Pascal (Inist)
- Ataxie, Hérédodégénérescence spinocérébelleuse de Friedreich, Oxygène, Pathologie du système nerveux.
Wicri :
- topic : Oxygène.

English descriptors

KwdEn :
- Adult, Ataxia, Female, Friedreich Ataxia (urine), Friedreich ataxia, Humans, Isoprostanes (urine), Male, Middle Aged, Nervous system diseases, Oxygen, Young Adult, ataxia, biomarker, neurogenetics, reactive oxygen species.
MESH :
- chemical , urine : Isoprostanes.
- urine : Friedreich Ataxia.
- Adult, Female, Humans, Male, Middle Aged, Young Adult.

Abstract

To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F2‐isoprostanes in patients with FA and healthy control subjects. Levels of urinary F2‐isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F2‐isoprostanes are not a useful biomarker in FA. © 2008 Movement Disorder Society.

Url:

https://api.istex.fr/document/B9848DC061D01E81BC49CAFF39D2976CBC0FF5A3/fulltext/pdf

DOI: 10.1002/mds.22038

Affiliations:

Le document en format XML

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<author><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name>
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<front><div type="abstract" xml:lang="en">To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F2‐isoprostanes in patients with FA and healthy control subjects. Levels of urinary F2‐isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F2‐isoprostanes are not a useful biomarker in FA. © 2008 Movement Disorder Society.</div>
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Movement Disorders (revue)

Urinary isoprostanes in Friedreich ataxia: Lack of correlation with disease features

Urinary isoprostanes in Friedreich ataxia: Lack of correlation with disease features

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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