Urinary Isoprostanes in Friedreich Ataxia : Lack of Correlation with Disease Features
Identifieur interne : 003635 ( Main/Merge ); précédent : 003634; suivant : 003636Urinary Isoprostanes in Friedreich Ataxia : Lack of Correlation with Disease Features
Auteurs : Lauren M. Myers [États-Unis] ; David R. Lynch [États-Unis] ; Jennifer M. Farmer [États-Unis] ; Lisa S. Friedman [États-Unis] ; John A. Lawson [États-Unis] ; Robert B. Wilson [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2008.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Oxygène.
English descriptors
- KwdEn :
Abstract
To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F2-isoprostanes in patients with FA and healthy control subjects. Levels of urinary F2-isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F2-isoprostanes are not a useful biomarker in FA.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 001079
- to stream PascalFrancis, to step Curation: 001C40
- to stream PascalFrancis, to step Checkpoint: 001027
Links to Exploration step
Pascal:08-0522211Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Urinary Isoprostanes in Friedreich Ataxia : Lack of Correlation with Disease Features</title><author><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M." last="Myers">Lauren M. Myers</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R." last="Lynch">David R. Lynch</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M." last="Farmer">Jennifer M. Farmer</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A." last="Lawson">John A. Lawson</name><affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Department of Pharmacology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B." last="Wilson">Robert B. Wilson</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">08-0522211</idno><date when="2008">2008</date><idno type="stanalyst">PASCAL 08-0522211 INIST</idno><idno type="RBID">Pascal:08-0522211</idno><idno type="wicri:Area/PascalFrancis/Corpus">001079</idno><idno type="wicri:Area/PascalFrancis/Curation">001C40</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001027</idno><idno type="wicri:doubleKey">0885-3185:2008:Myers L:urinary:isoprostanes:in</idno><idno type="wicri:Area/Main/Merge">003635</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Urinary Isoprostanes in Friedreich Ataxia : Lack of Correlation with Disease Features</title><author><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M." last="Myers">Lauren M. Myers</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R." last="Lynch">David R. Lynch</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M." last="Farmer">Jennifer M. Farmer</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Neurology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Pediatrics, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>The Children's Hospital of Philadelphia</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A." last="Lawson">John A. Lawson</name><affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Department of Pharmacology, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B." last="Wilson">Robert B. Wilson</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine</s1><s2>Philadelphia, Pennsylvania</s2><s3>USA</s3><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ataxia</term><term>Friedreich ataxia</term><term>Nervous system diseases</term><term>Oxygen</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Hérédodégénérescence spinocérébelleuse de Friedreich</term><term>Ataxie</term><term>Pathologie du système nerveux</term><term>Oxygène</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Oxygène</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F<sub>2</sub>-isoprostanes in patients with FA and healthy control subjects. Levels of urinary F<sub>2</sub>-isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F<sub>2</sub>-isoprostanes are not a useful biomarker in FA.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M." last="Myers">Lauren M. Myers</name></region><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M." last="Farmer">Jennifer M. Farmer</name><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M." last="Farmer">Jennifer M. Farmer</name><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M." last="Farmer">Jennifer M. Farmer</name><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S." last="Friedman">Lisa S. Friedman</name><name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A." last="Lawson">John A. Lawson</name><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R." last="Lynch">David R. Lynch</name><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R." last="Lynch">David R. Lynch</name><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R." last="Lynch">David R. Lynch</name><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M." last="Myers">Lauren M. Myers</name><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M." last="Myers">Lauren M. Myers</name><name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B." last="Wilson">Robert B. Wilson</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003635 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003635 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= Pascal:08-0522211
|texte= Urinary Isoprostanes in Friedreich Ataxia : Lack of Correlation with Disease Features
}}
| This area was generated with Dilib version V0.6.23. |  |