MovDisordV3, Ncbi, Checkpoint, bibRecord, 002246

Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.

Identifieur interne : 002246 ( Ncbi/Checkpoint ); précédent : 002245; suivant : 002247

Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.

Auteurs : Lauren M. Myers [États-Unis] ; David R. Lynch ; Jennifer M. Farmer ; Lisa S. Friedman ; John A. Lawson ; Robert B. Wilson

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.

RBID : pubmed:18671287

English descriptors

KwdEn :
- Adult, Female, Friedreich Ataxia (urine), Humans, Isoprostanes (urine), Male, Middle Aged, Young Adult.
MESH :
- chemical , urine : Isoprostanes.
- urine : Friedreich Ataxia.
- Adult, Female, Humans, Male, Middle Aged, Young Adult.

Abstract

To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F(2)-isoprostanes in patients with FA and healthy control subjects. Levels of urinary F(2)-isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F(2)-isoprostanes are not a useful biomarker in FA.

DOI: 10.1002/mds.22038
PubMed: 18671287

Affiliations:

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pubmed:18671287

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.</title>
<author><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M" last="Myers">Lauren M. Myers</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R" last="Lynch">David R. Lynch</name>
</author>
<author><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M" last="Farmer">Jennifer M. Farmer</name>
</author>
<author><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S" last="Friedman">Lisa S. Friedman</name>
</author>
<author><name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A" last="Lawson">John A. Lawson</name>
</author>
<author><name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B" last="Wilson">Robert B. Wilson</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="doi">10.1002/mds.22038</idno>
<idno type="RBID">pubmed:18671287</idno>
<idno type="pmid">18671287</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.</title>
<author><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M" last="Myers">Lauren M. Myers</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R" last="Lynch">David R. Lynch</name>
</author>
<author><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M" last="Farmer">Jennifer M. Farmer</name>
</author>
<author><name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S" last="Friedman">Lisa S. Friedman</name>
</author>
<author><name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A" last="Lawson">John A. Lawson</name>
</author>
<author><name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B" last="Wilson">Robert B. Wilson</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008" type="published">2008</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Friedreich Ataxia (urine)</term>
<term>Humans</term>
<term>Isoprostanes (urine)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Isoprostanes</term>
</keywords>
<keywords scheme="MESH" qualifier="urine" xml:lang="en"><term>Friedreich Ataxia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To assess the utility of urinary isoprostanes as markers of oxidative injury in Friedreich ataxia (FA), we compared levels of urinary F(2)-isoprostanes in patients with FA and healthy control subjects. Levels of urinary F(2)-isoprostanes in FA patients were not different from controls and were not significantly associated with age, GAA repeat length, disability level, or the use of antioxidants. Thus, urinary F(2)-isoprostanes are not a useful biomarker in FA.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Pennsylvanie</li>
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</list>
<tree><noCountry><name sortKey="Farmer, Jennifer M" sort="Farmer, Jennifer M" uniqKey="Farmer J" first="Jennifer M" last="Farmer">Jennifer M. Farmer</name>
<name sortKey="Friedman, Lisa S" sort="Friedman, Lisa S" uniqKey="Friedman L" first="Lisa S" last="Friedman">Lisa S. Friedman</name>
<name sortKey="Lawson, John A" sort="Lawson, John A" uniqKey="Lawson J" first="John A" last="Lawson">John A. Lawson</name>
<name sortKey="Lynch, David R" sort="Lynch, David R" uniqKey="Lynch D" first="David R" last="Lynch">David R. Lynch</name>
<name sortKey="Wilson, Robert B" sort="Wilson, Robert B" uniqKey="Wilson R" first="Robert B" last="Wilson">Robert B. Wilson</name>
</noCountry>
<country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Myers, Lauren M" sort="Myers, Lauren M" uniqKey="Myers L" first="Lauren M" last="Myers">Lauren M. Myers</name>
</region>
</country>
</tree>
</affiliations>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.

Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki