MovDisordV3, Main, Curation, bibRecord, 002981

Autonomic dysfunction in different subtypes of multiple system atrophy

Identifieur interne : 002981 ( Main/Curation ); précédent : 002980; suivant : 002982

Autonomic dysfunction in different subtypes of multiple system atrophy

Auteurs : Claudia Schmidt [Allemagne] ; Birgit Herting [Allemagne] ; Silke Prieur [Allemagne] ; Susann Junghanns [Allemagne] ; Katherine Schweitzer [Allemagne] ; Christoph Globas [Allemagne] ; Ludger Schöls [Allemagne] ; Heinz Reichmann [Allemagne] ; Daniela Berg [Allemagne] ; Tjalf Ziemssen [Allemagne]

Source :

Movement Disorders [ 0885-3185 ] ; 2008-09-15.

RBID : ISTEX:725C3392D497BA6250201A73255EA228FF648036

Descripteurs français

Pascal (Inist)
- Atrophie multisystématisée, Homme, Pathologie du système nerveux, Soustype, Système nerveux autonome, Trouble fonctionnel.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Autonomic Nervous System (physiopathology), Autonomic Nervous System Diseases (diagnosis), Autonomic Nervous System Diseases (etiology), Autonomic nervous system, Dysfunction, Female, Human, Humans, Interview, Psychological, MSA subtypes, Male, Middle Aged, Multiple System Atrophy (classification), Multiple System Atrophy (complications), Multiple system atrophy, Nervous system diseases, Parkinson Disease (complications), Severity of Illness Index, Subtype, Supranuclear Palsy, Progressive (complications), autonomic dysfunction, autonomic nervous system, autonomic testing, multiple system atrophy, progressive supranuclear palsy.
MESH :
- classification : Multiple System Atrophy.
- complications : Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy, Progressive.
- diagnosis : Autonomic Nervous System Diseases.
- etiology : Autonomic Nervous System Diseases.
- physiopathology : Autonomic Nervous System.
- Aged, Aged, 80 and over, Female, Humans, Interview, Psychological, Male, Middle Aged, Severity of Illness Index.

Abstract

Multiple system atrophy (MSA) can clinically be divided into the cerebellar (MSA‐C) and the parkinsonian (MSA‐P) variant. However, till now, it is unknown whether autonomic dysfunction in these two entities differs regarding severity and profile. We compared the pattern of autonomic dysfunction in 12 patients with MSA‐C and 26 with MSA‐P in comparison with 27 age‐ and sex‐matched healthy controls using a standard battery of autonomic function tests and a structured anamnesis of the autonomic nervous system. MSA‐P patients complained significantly more often about the symptoms of autonomic dysfunctions than MSA‐C patients, especially regarding vasomotor, secretomotor, and gastrointestinal subsystems. However, regarding cardiovascular, sudomotor pupil, urogenital, and sleep subsystems, there were no significant quantitative or qualitative differences as analyzed by autonomic anamnesis and testing. Our results suggest that there are only minor differences in the pattern of autonomic dysfunction between the two clinical MSA phenotypes. © 2008 Movement Disorder Society

Url:

DOI: 10.1002/mds.22187

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ISTEX:725C3392D497BA6250201A73255EA228FF648036

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<term>Autonomic Nervous System (physiopathology)</term>
<term>Autonomic Nervous System Diseases (diagnosis)</term>
<term>Autonomic Nervous System Diseases (etiology)</term>
<term>Autonomic nervous system</term>
<term>Dysfunction</term>
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<term>Multiple System Atrophy (complications)</term>
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<term>Nervous system diseases</term>
<term>Parkinson Disease (complications)</term>
<term>Severity of Illness Index</term>
<term>Subtype</term>
<term>Supranuclear Palsy, Progressive (complications)</term>
<term>autonomic dysfunction</term>
<term>autonomic nervous system</term>
<term>autonomic testing</term>
<term>multiple system atrophy</term>
<term>progressive supranuclear palsy</term>
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<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Multiple system atrophy (MSA) can clinically be divided into the cerebellar (MSA‐C) and the parkinsonian (MSA‐P) variant. However, till now, it is unknown whether autonomic dysfunction in these two entities differs regarding severity and profile. We compared the pattern of autonomic dysfunction in 12 patients with MSA‐C and 26 with MSA‐P in comparison with 27 age‐ and sex‐matched healthy controls using a standard battery of autonomic function tests and a structured anamnesis of the autonomic nervous system. MSA‐P patients complained significantly more often about the symptoms of autonomic dysfunctions than MSA‐C patients, especially regarding vasomotor, secretomotor, and gastrointestinal subsystems. However, regarding cardiovascular, sudomotor pupil, urogenital, and sleep subsystems, there were no significant quantitative or qualitative differences as analyzed by autonomic anamnesis and testing. Our results suggest that there are only minor differences in the pattern of autonomic dysfunction between the two clinical MSA phenotypes. © 2008 Movement Disorder Society</div>
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<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson Research group, Department of Neurology, University of Dresden</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Parkinson Research group, Department of Neurology, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and neuroendocrinological laboratory, University of Dresden</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0487392</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0487392 INIST</idno>
<idno type="RBID">Pascal:08-0487392</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001105</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001C14</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001352</idno>
<idno type="wicri:doubleKey">0885-3185:2008:Schmidt C:autonomic:dysfunction:in</idno>
<idno type="wicri:Area/Main/Merge">003960</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Autonomic Dysfunction in Different Subtypes of Multiple System Atrophy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and neuroendocrinological laboratory, University of Dresden</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson Research group, Department of Neurology, University of Dresden</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Parkinson Research group, Department of Neurology, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and neuroendocrinological laboratory, University of Dresden</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson Research group, Department of Neurology, University of Dresden</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Parkinson Research group, Department of Neurology, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Globas, Christoph" sort="Globas, Christoph" uniqKey="Globas C" first="Christoph" last="Globas">Christoph Globas</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson Research group, Department of Neurology, University of Dresden</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Parkinson Research group, Department of Neurology, University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</s1>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and neuroendocrinological laboratory, University of Dresden</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Autonomic nervous system</term>
<term>Dysfunction</term>
<term>Multiple system atrophy</term>
<term>Nervous system diseases</term>
<term>Subtype</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Atrophie multisystématisée</term>
<term>Pathologie du   système nerveux</term>
<term>Trouble fonctionnel</term>
<term>Soustype</term>
<term>Système nerveux autonome</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Multiple system atrophy (MSA) can clinically be divided into the cerebellar (MSA-C) and the parkinsonian (MSA-P) variant. However, till now, it is unknown whether autonomic dysfunction in these two entities differs regarding severity and profile. We compared the pattern of autonomic dysfunction in 12 patients with MSA-C and 26 with MSA-P in comparison with 27 age- and sex-matched healthy controls using a standard battery of autonomic function tests and a structured anamnesis of the autonomic nervous system. MSA-P patients complained significantly more often about the symptoms of autonomic dysfunctions than MSA-C patients, especially regarding vasomotor, secretomotor, and gastrointestinal subsystems. However, regarding cardiovascular, sudomotor pupil, urogenital, and sleep subsystems, there were no significant quantitative or qualitative differences as analyzed by autonomic anamnesis and testing. Our results suggest that there are only minor differences in the pattern of autonomic dysfunction between the two clinical MSA phenotypes.</div>
</front>
</TEI>
</INIST>
<INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Center of Neurology, Department of Neurodegeneration and Hertie-Institute of Clinical Brain Research, University of Tühingen</s1>
<s2>Tühingen</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Tühingen</wicri:noRegion>
<wicri:noRegion>University of Tühingen</wicri:noRegion>
<wicri:noRegion>Tühingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Center of Neurology, Department of Neurodegeneration and Hertie-Institute of Clinical Brain Research, University of Tühingen</s1>
<s2>Tühingen</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Tühingen</wicri:noRegion>
<wicri:noRegion>University of Tühingen</wicri:noRegion>
<wicri:noRegion>Tühingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0536664</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0536664 INIST</idno>
<idno type="RBID">Pascal:08-0536664</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001071</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001C48</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001351</idno>
<idno type="wicri:doubleKey">0885-3185:2008:Schmidt C:autonomic:dysfunction:in</idno>
<idno type="wicri:Area/Main/Merge">003959</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Center of Neurology, Department of Neurodegeneration and Hertie-Institute of Clinical Brain Research, University of Tühingen</s1>
<s2>Tühingen</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Tühingen</wicri:noRegion>
<wicri:noRegion>University of Tühingen</wicri:noRegion>
<wicri:noRegion>Tühingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Center of Neurology, Department of Neurodegeneration and Hertie-Institute of Clinical Brain Research, University of Tühingen</s1>
<s2>Tühingen</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Tühingen</wicri:noRegion>
<wicri:noRegion>University of Tühingen</wicri:noRegion>
<wicri:noRegion>Tühingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</s1>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dysfunction</term>
<term>Human</term>
<term>Nervous system diseases</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Pathologie du   système nerveux</term>
<term>Trouble fonctionnel</term>
<term>Homme</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The most important features that characterize and differentiate progressive supranuclear palsy (PSP) from other parkinsonian syndromes are postural instability, supranuclear gaze palsy, pseudobulbar palsy, and cognitive disturbances. Although it has been reported that significant autonomic dysfunction is an exclusionary feature for PSP diagnosis, we could demonstrate in this study using semiquantitative clinical interview and cardiovascular testing that both PSP and idiopathic Parkinson's disease (PD) patients can present with significant autonomic dysfunction. The parasympathetic cardiovascular system seems to be involved to a similar extent in PD and PSP patients, whereas sympathetic cardiovascular dysfunction is more frequent and severe in PD patients, but can also be found in PSP patients. Our findings have a profound implication on the diagnosis and treatment of PSP patients.</div>
</front>
</TEI>
</INIST>
<ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Autonomic dysfunction in different subtypes of multiple system atrophy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
</author>
<author><name sortKey="Globas, Christoph" sort="Globas, Christoph" uniqKey="Globas C" first="Christoph" last="Globas">Christoph Globas</name>
</author>
<author><name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
</author>
</titleStmt>
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<idno type="RBID">ISTEX:725C3392D497BA6250201A73255EA228FF648036</idno>
<date when="2008" year="2008">2008</date>
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<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:18661564</idno>
<idno type="wicri:Area/PubMed/Corpus">002135</idno>
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<idno type="wicri:Area/Ncbi/Checkpoint">002228</idno>
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</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Autonomic dysfunction in different subtypes of multiple system atrophy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Parkinson Research group, Department of Neurology, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Parkinson Research group, Department of Neurology, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:regionArea>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Globas, Christoph" sort="Globas, Christoph" uniqKey="Globas C" first="Christoph" last="Globas">Christoph Globas</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:regionArea>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:regionArea>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Parkinson Research group, Department of Neurology, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurodegenerative Disorders, Hertie Institute of Clinical Brain Research, University of Tübingen</wicri:regionArea>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
<wicri:noRegion>University of Tübingen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and neuroendocrinological laboratory, University of Dresden</wicri:regionArea>
<wicri:noRegion>University of Dresden</wicri:noRegion>
<wicri:noRegion>University of Dresden</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-09-15">2008-09-15</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">12</biblScope>
<biblScope unit="page" from="1766">1766</biblScope>
<biblScope unit="page" to="1772">1772</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">725C3392D497BA6250201A73255EA228FF648036</idno>
<idno type="DOI">10.1002/mds.22187</idno>
<idno type="ArticleID">MDS22187</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Autonomic Nervous System (physiopathology)</term>
<term>Autonomic Nervous System Diseases (diagnosis)</term>
<term>Autonomic Nervous System Diseases (etiology)</term>
<term>Female</term>
<term>Humans</term>
<term>MSA subtypes</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multiple System Atrophy (classification)</term>
<term>Multiple System Atrophy (complications)</term>
<term>autonomic dysfunction</term>
<term>autonomic nervous system</term>
<term>multiple system atrophy</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Multiple System Atrophy</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Multiple System Atrophy</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Autonomic Nervous System</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
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</teiHeader>
<front><div type="abstract" xml:lang="en">Multiple system atrophy (MSA) can clinically be divided into the cerebellar (MSA‐C) and the parkinsonian (MSA‐P) variant. However, till now, it is unknown whether autonomic dysfunction in these two entities differs regarding severity and profile. We compared the pattern of autonomic dysfunction in 12 patients with MSA‐C and 26 with MSA‐P in comparison with 27 age‐ and sex‐matched healthy controls using a standard battery of autonomic function tests and a structured anamnesis of the autonomic nervous system. MSA‐P patients complained significantly more often about the symptoms of autonomic dysfunctions than MSA‐C patients, especially regarding vasomotor, secretomotor, and gastrointestinal subsystems. However, regarding cardiovascular, sudomotor pupil, urogenital, and sleep subsystems, there were no significant quantitative or qualitative differences as analyzed by autonomic anamnesis and testing. Our results suggest that there are only minor differences in the pattern of autonomic dysfunction between the two clinical MSA phenotypes. © 2008 Movement Disorder Society</div>
</front>
</TEI>
</ISTEX>
<ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Autonomic dysfunction in patients with progressive supranuclear palsy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:635C6BB39F23BFFA12F896E004C3ADA23D1DF6E0</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1002/mds.22289</idno>
<idno type="url">https://api.istex.fr/document/635C6BB39F23BFFA12F896E004C3ADA23D1DF6E0/fulltext/pdf</idno>
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<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:18792126</idno>
<idno type="wicri:Area/PubMed/Corpus">002019</idno>
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<idno type="wicri:Area/PubMed/Checkpoint">002415</idno>
<idno type="wicri:Area/Ncbi/Merge">002344</idno>
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<idno type="wicri:Area/Ncbi/Checkpoint">002344</idno>
<idno type="wicri:Area/Main/Merge">003560</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Autonomic dysfunction in patients with progressive supranuclear palsy</title>
<author><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Herting, Birgit" sort="Herting, Birgit" uniqKey="Herting B" first="Birgit" last="Herting">Birgit Herting</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Prieur, Silke" sort="Prieur, Silke" uniqKey="Prieur S" first="Silke" last="Prieur">Silke Prieur</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Junghanns, Susann" sort="Junghanns, Susann" uniqKey="Junghanns S" first="Susann" last="Junghanns">Susann Junghanns</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center of Neurology, Department of Neurodegeneration and Hertie‐Institute of Clinical Brain Research, University of Tübingen, Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Movement Disorders Research Group, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center of Neurology, Department of Neurodegeneration and Hertie‐Institute of Clinical Brain Research, University of Tübingen, Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Autonomic and Neuroendocrinological Laboratory (ANF), University Clinic Carl Gustav Carus, Dresden University of Technology</wicri:regionArea>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
<wicri:noRegion>Dresden University of Technology</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-10-30">2008-10-30</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">14</biblScope>
<biblScope unit="page" from="2083">2083</biblScope>
<biblScope unit="page" to="2089">2089</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">635C6BB39F23BFFA12F896E004C3ADA23D1DF6E0</idno>
<idno type="DOI">10.1002/mds.22289</idno>
<idno type="ArticleID">MDS22289</idno>
</biblStruct>
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<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Autonomic Nervous System Diseases (etiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Interview, Psychological</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>Severity of Illness Index</term>
<term>Supranuclear Palsy, Progressive (complications)</term>
<term>autonomic dysfunction</term>
<term>autonomic testing</term>
<term>progressive supranuclear palsy</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Autonomic Nervous System Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Interview, Psychological</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Severity of Illness Index</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The most important features that characterize and differentiate progressive supranuclear palsy (PSP) from other parkinsonian syndromes are postural instability, supranuclear gaze palsy, pseudobulbar palsy, and cognitive disturbances. Although it has been reported that significant autonomic dysfunction is an exclusionary feature for PSP diagnosis, we could demonstrate in this study using semiquantitative clinical interview and cardiovascular testing that both PSP and idiopathic Parkinson's disease (PD) patients can present with significant autonomic dysfunction. The parasympathetic cardiovascular system seems to be involved to a similar extent in PD and PSP patients, whereas sympathetic cardiovascular dysfunction is more frequent and severe in PD patients, but can also be found in PSP patients. Our findings have a profound implication on the diagnosis and treatment of PSP patients. © 2008 Movement Disorder Society</div>
</front>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Autonomic dysfunction in different subtypes of multiple system atrophy

Autonomic dysfunction in different subtypes of multiple system atrophy

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