MovDisordV3, PascalFrancis, Checkpoint, bibRecord, 001351

Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy

Identifieur interne : 001351 ( PascalFrancis/Checkpoint ); précédent : 001350; suivant : 001352

Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy

Auteurs : Claudia Schmidt [Allemagne] ; Birgit Herting [Allemagne] ; Silke Prieur [Allemagne] ; Susann Junghanns [Allemagne] ; Katherine Schweitzer [Allemagne] ; Heinz Reichmann [Allemagne] ; Daniela Berg [Allemagne] ; Tjalf Ziemssen [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2008.

RBID : Pascal:08-0536664

Descripteurs français

Pascal (Inist)
- Pathologie du système nerveux, Trouble fonctionnel, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Dysfunction, Human, Nervous system diseases.

Abstract

The most important features that characterize and differentiate progressive supranuclear palsy (PSP) from other parkinsonian syndromes are postural instability, supranuclear gaze palsy, pseudobulbar palsy, and cognitive disturbances. Although it has been reported that significant autonomic dysfunction is an exclusionary feature for PSP diagnosis, we could demonstrate in this study using semiquantitative clinical interview and cardiovascular testing that both PSP and idiopathic Parkinson's disease (PD) patients can present with significant autonomic dysfunction. The parasympathetic cardiovascular system seems to be involved to a similar extent in PD and PSP patients, whereas sympathetic cardiovascular dysfunction is more frequent and severe in PD patients, but can also be found in PSP patients. Our findings have a profound implication on the diagnosis and treatment of PSP patients.

Affiliations:

Allemagne

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Pascal:08-0536664

Le document en format XML

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<front><div type="abstract" xml:lang="en">The most important features that characterize and differentiate progressive supranuclear palsy (PSP) from other parkinsonian syndromes are postural instability, supranuclear gaze palsy, pseudobulbar palsy, and cognitive disturbances. Although it has been reported that significant autonomic dysfunction is an exclusionary feature for PSP diagnosis, we could demonstrate in this study using semiquantitative clinical interview and cardiovascular testing that both PSP and idiopathic Parkinson's disease (PD) patients can present with significant autonomic dysfunction. The parasympathetic cardiovascular system seems to be involved to a similar extent in PD and PSP patients, whereas sympathetic cardiovascular dysfunction is more frequent and severe in PD patients, but can also be found in PSP patients. Our findings have a profound implication on the diagnosis and treatment of PSP patients.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy

Autonomic Dysfunction in Patients with Progressive Supranuclear Palsy

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