MovDisordV3, Main, Curation, bibRecord, 002936

Cognitive dysfunction in Nigerians with Parkinson's disease

Identifieur interne : 002936 ( Main/Curation ); précédent : 002935; suivant : 002937

Cognitive dysfunction in Nigerians with Parkinson's disease

Auteurs : Rufus O. Akinyemi [Nigeria] ; Njideka N. Okubadejo [Nigeria] ; Joshua O. Akinyemi [Nigeria] ; Mayowa O. Owolabi [Nigeria] ; Lukman F. Owolabi [Nigeria] ; Adesola Ogunniyi [Nigeria]

Source :

Movement Disorders [ 0885-3185 ] ; 2008-07-30.

RBID : ISTEX:FF0A2A7AC43B3905CC63708C27059C11F9D0DA05

Descripteurs français

Pascal (Inist)
- Africain, Maladie de Parkinson, Pathologie du système nerveux, Trouble cognitif.
Wicri :
- geographic : Nigeria.

English descriptors

KwdEn :
- Adult, African, Africans, Age Factors, Age of Onset, Aged, Aged, 80 and over, Cognition Disorders (epidemiology), Cognition Disorders (etiology), Cognitive disorder, Female, Humans, Hypokinesia (etiology), Language Tests, Male, Middle Aged, Motor Activity, Nervous system diseases, Neuropsychological Tests, Nigeria (epidemiology), Nigerians, Parkinson Disease (epidemiology), Parkinson Disease (psychology), Parkinson disease, Parkinson's disease, Prefrontal Cortex (physiopathology), Tremor (etiology), cognitive dysfunction.
MESH :
- geographic , epidemiology : Nigeria.
- epidemiology : Cognition Disorders, Parkinson Disease.
- etiology : Cognition Disorders, Hypokinesia, Tremor.
- physiopathology : Prefrontal Cortex.
- psychology : Parkinson Disease.
- Adult, Age Factors, Age of Onset, Aged, Aged, 80 and over, Female, Humans, Language Tests, Male, Middle Aged, Motor Activity, Neuropsychological Tests.

Abstract

Despite the original description of Parkinson's disease (PD) as a disorder in which “the senses and intellect remain uninjured,” there is now sufficient evidence that cognitive dysfunction does occur. This research determined the frequency, pattern, and predictors of cognitive dysfunction among 51 Nigerian patients with PD compared with 50 demographically matched controls using the modified Community Screening Instrument for Dementia (CSI‘D’) and selected items from the Ibadan Neuropsychological Battery (I‐NB). In all, 21.6% patients with PD (4% of controls) exhibited cognitive impairment (P = 0.008) defined, for the purposes of this study, as total modified CSI‘D’ score below 2 SD of the mean score of the control group. Cognitive dysfunction in patients with PD encompassed memory, language, and executive dysfunction. Correlates of cognitive dysfunction included older age at PD onset (P = 0.001), older current age (P < 0.001), and higher UPDRS motor score (P = 0.005). After logistic regression, older age at onset of PD was the only independent predictor of cognitive dysfunction. (O.R = 1.29; 95% CI = 1.08–1.57, P = 0.006). Cognitive dysfunction occurs more frequently in Nigerians with PD compared to controls. Older age at disease onset is an important determinant of cognitive dysfunction in PD. © 2008 Movement Disorder Society

Url:

https://api.istex.fr/document/FF0A2A7AC43B3905CC63708C27059C11F9D0DA05/fulltext/pdf

DOI: 10.1002/mds.22087

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ISTEX:FF0A2A7AC43B3905CC63708C27059C11F9D0DA05

Le document en format XML

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<front><div type="abstract" xml:lang="en">Despite the original description of Parkinson's disease (PD) as a disorder in which “the senses and intellect remain uninjured,” there is now sufficient evidence that cognitive dysfunction does occur. This research determined the frequency, pattern, and predictors of cognitive dysfunction among 51 Nigerian patients with PD compared with 50 demographically matched controls using the modified Community Screening Instrument for Dementia (CSI‘D’) and selected items from the Ibadan Neuropsychological Battery (I‐NB). In all, 21.6% patients with PD (4% of controls) exhibited cognitive impairment (P = 0.008) defined, for the purposes of this study, as total modified CSI‘D’ score below 2 SD of the mean score of the control group. Cognitive dysfunction in patients with PD encompassed memory, language, and executive dysfunction. Correlates of cognitive dysfunction included older age at PD onset (P = 0.001), older current age (P < 0.001), and higher UPDRS motor score (P = 0.005). After logistic regression, older age at onset of PD was the only independent predictor of cognitive dysfunction. (O.R = 1.29; 95% CI = 1.08–1.57, P = 0.006). Cognitive dysfunction occurs more frequently in Nigerians with PD compared to controls. Older age at disease onset is an important determinant of cognitive dysfunction in PD. © 2008 Movement Disorder Society</div>
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<series><title level="j" type="main">Movement disorders</title>
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<front><div type="abstract" xml:lang="en">Despite the original description of Parkinson's disease (PD) as a disorder in which "the senses and intellect remain uninjured," there is now sufficient evidence that cognitive dysfunction does occur. This research determined the frequency, pattern, and predictors of cognitive dysfunction among 51 Nigerian patients with PD compared with 50 demographically matched controls using the modified Community Screening Instrument for Dementia (CSI'D') and selected items from the Ibadan Neuropsychological Battery (I-NB). In all, 21.6% patients with PD (4% of controls) exhibited cognitive impairment (P = 0.008) defined, for the purposes of this study, as total modified CSI'D' score below 2 SD of the mean score of the control group. Cognitive dysfunction in patients with PD encompassed memory, language, and executive dysfunction. Correlates of cognitive dysfunction included older age at PD onset (P = 0.001), older current age (P < 0.001), and higher UPDRS motor score (P = 0.005). After logistic regression, older age at onset of PD was the only independent predictor of cognitive dysfunction. (O.R = 1.29; 95% CI = 1.08-1.57, P - 0.006). Cognitive dysfunction occurs more frequently in Nigerians with PD compared to controls. Older age at disease onset is an important determinant of cognitive dysfunction in PD.</div>
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<front><div type="abstract" xml:lang="en">Despite the original description of Parkinson's disease (PD) as a disorder in which “the senses and intellect remain uninjured,” there is now sufficient evidence that cognitive dysfunction does occur. This research determined the frequency, pattern, and predictors of cognitive dysfunction among 51 Nigerian patients with PD compared with 50 demographically matched controls using the modified Community Screening Instrument for Dementia (CSI‘D’) and selected items from the Ibadan Neuropsychological Battery (I‐NB). In all, 21.6% patients with PD (4% of controls) exhibited cognitive impairment (P = 0.008) defined, for the purposes of this study, as total modified CSI‘D’ score below 2 SD of the mean score of the control group. Cognitive dysfunction in patients with PD encompassed memory, language, and executive dysfunction. Correlates of cognitive dysfunction included older age at PD onset (P = 0.001), older current age (P < 0.001), and higher UPDRS motor score (P = 0.005). After logistic regression, older age at onset of PD was the only independent predictor of cognitive dysfunction. (O.R = 1.29; 95% CI = 1.08–1.57, P = 0.006). Cognitive dysfunction occurs more frequently in Nigerians with PD compared to controls. Older age at disease onset is an important determinant of cognitive dysfunction in PD. © 2008 Movement Disorder Society</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Cognitive dysfunction in Nigerians with Parkinson's disease

Cognitive dysfunction in Nigerians with Parkinson's disease

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