Set‐shifting and behavioral dysfunction in primary focal dystonia
Identifieur interne : 002632 ( Main/Curation ); précédent : 002631; suivant : 002633Set‐shifting and behavioral dysfunction in primary focal dystonia
Auteurs : Paulo Bugalho [Portugal] ; Bernardo Corrêa [Portugal] ; João Guimarães [Portugal] ; Miguel Xavier [Portugal]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Attention (physiology), Behavioral Symptoms (etiology), Cognitive disorder, Dysfunction, Dystonia, Dystonic Disorders (complications), Female, Humans, Male, Middle Aged, Nervous system diseases, Neuropsychological Tests, Obsessive compulsive disorder, Set (Psychology), Severity of Illness Index, executive dysfunction, frontostriatal circuits., obsessive compulsive symptoms, primary dystonia.
- MESH :
- complications : Dystonic Disorders.
- etiology : Behavioral Symptoms.
- physiology : Attention.
- Female, Humans, Male, Middle Aged, Neuropsychological Tests, Set (Psychology), Severity of Illness Index.
Abstract
The occurrence of cognitive and behavioral symptoms in patients with primary dystonia remains a matter of debate. We compared 45 patients with primary dystonia with 27 control subjects for performance on neuropsychological tasks with a load on executive‐Wisconsin Card Sorting Test (WCST) and Stroop test, and visuospatial‐Benton's visual retention test (BVRT) and Block assembly test from Wechsler Adult Intelligence Scale BAT‐functions, as well as for intensity of obsessive‐compulsive symptoms (Yale Brown Obsessive Compulsive Scale, Y‐BOCS). Correlation analysis was performed between neuropsychological performance, dystonia characteristics (duration, age of onset) and severity (Unified Dystonia Rating Scale, UDRS), and Y‐BOCS. Patients made more perseverative errors on the WCST (P = 0.042) and had a higher mean Y‐BOCS (P = 0.003) score than controls. Timed tests (BVRT, BAT, Stroop test) correlated with UDRS. Y‐BOCS, WCST, and UDRS scores were not significantly correlated with one another.These results suggest that patients with primary dystonia may have set‐shifting deficits and a higher intensity of obsessive compulsive symptoms when compared to healthy subjects. This may reflect a pattern of complex neurophysiological dysfunction involving dorsolateral, orbitofrontal, and motor frontostriatal circuits. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21784
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-01-30">2008-01-30</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="200">200</biblScope><biblScope unit="page" to="206">206</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">0D92C89C99720074C60D8B7075AB71C3EA5F1DEC</idno><idno type="DOI">10.1002/mds.21784</idno><idno type="ArticleID">MDS21784</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Attention (physiology)</term><term>Behavioral Symptoms (etiology)</term><term>Cognitive disorder</term><term>Dysfunction</term><term>Dystonia</term><term>Dystonic Disorders (complications)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Neuropsychological Tests</term><term>Obsessive compulsive disorder</term><term>Set (Psychology)</term><term>Severity of Illness Index</term><term>executive dysfunction</term><term>frontostriatal circuits.</term><term>obsessive compulsive symptoms</term><term>primary dystonia</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Dystonic Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Behavioral Symptoms</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Attention</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Set (Psychology)</term><term>Severity of Illness Index</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Dystonie</term><term>Obsession compulsion</term><term>Pathologie du système nerveux</term><term>Trouble cognitif</term><term>Trouble fonctionnel</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The occurrence of cognitive and behavioral symptoms in patients with primary dystonia remains a matter of debate. We compared 45 patients with primary dystonia with 27 control subjects for performance on neuropsychological tasks with a load on executive‐Wisconsin Card Sorting Test (WCST) and Stroop test, and visuospatial‐Benton's visual retention test (BVRT) and Block assembly test from Wechsler Adult Intelligence Scale BAT‐functions, as well as for intensity of obsessive‐compulsive symptoms (Yale Brown Obsessive Compulsive Scale, Y‐BOCS). Correlation analysis was performed between neuropsychological performance, dystonia characteristics (duration, age of onset) and severity (Unified Dystonia Rating Scale, UDRS), and Y‐BOCS. Patients made more perseverative errors on the WCST (P = 0.042) and had a higher mean Y‐BOCS (P = 0.003) score than controls. Timed tests (BVRT, BAT, Stroop test) correlated with UDRS. Y‐BOCS, WCST, and UDRS scores were not significantly correlated with one another.These results suggest that patients with primary dystonia may have set‐shifting deficits and a higher intensity of obsessive compulsive symptoms when compared to healthy subjects. This may reflect a pattern of complex neurophysiological dysfunction involving dorsolateral, orbitofrontal, and motor frontostriatal circuits. © 2007 Movement Disorder Society</div></front></TEI><double idat="0885-3185:2008:Bugalho P:set:shifting:and"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Set-Shifting and Behavioral Dysfunction in Primary Focal Dystonia</title><author><name sortKey="Bugalho, Paulo" sort="Bugalho, Paulo" uniqKey="Bugalho P" first="Paulo" last="Bugalho">Paulo Bugalho</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Correa, Bernardo" sort="Correa, Bernardo" uniqKey="Correa B" first="Bernardo" last="Correa">Bernardo Correa</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Guimaraes, Joao" sort="Guimaraes, Joao" uniqKey="Guimaraes J" first="Joao" last="Guimaraes">Joao Guimaraes</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Xavier, Miguel" sort="Xavier, Miguel" uniqKey="Xavier M" first="Miguel" last="Xavier">Miguel Xavier</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">08-0133661</idno><date when="2008">2008</date><idno type="stanalyst">PASCAL 08-0133661 INIST</idno><idno type="RBID">Pascal:08-0133661</idno><idno type="wicri:Area/PascalFrancis/Corpus">001391</idno><idno type="wicri:Area/PascalFrancis/Curation">001928</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001096</idno><idno type="wicri:doubleKey">0885-3185:2008:Bugalho P:set:shifting:and</idno><idno type="wicri:Area/Main/Merge">003704</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Set-Shifting and Behavioral Dysfunction in Primary Focal Dystonia</title><author><name sortKey="Bugalho, Paulo" sort="Bugalho, Paulo" uniqKey="Bugalho P" first="Paulo" last="Bugalho">Paulo Bugalho</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Correa, Bernardo" sort="Correa, Bernardo" uniqKey="Correa B" first="Bernardo" last="Correa">Bernardo Correa</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Guimaraes, Joao" sort="Guimaraes, Joao" uniqKey="Guimaraes J" first="Joao" last="Guimaraes">Joao Guimaraes</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Xavier, Miguel" sort="Xavier, Miguel" uniqKey="Xavier M" first="Miguel" last="Xavier">Miguel Xavier</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Faculdade de Ciências Médicas, Universidade Nova de Lisboa</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cognitive disorder</term><term>Dysfunction</term><term>Dystonia</term><term>Nervous system diseases</term><term>Obsessive compulsive disorder</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Dystonie</term><term>Trouble cognitif</term><term>Obsession compulsion</term><term>Pathologie du système nerveux</term><term>Trouble fonctionnel</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">: The occurrence of cognitive and behavioral symptoms in patients with primary dystonia remains a matter of debate. We compared 45 patients with primary dystonia with 27 control subjects for performance on neuropsychological tasks with a load on executive-Wisconsin Card Sorting Test (WCST) and Stroop test, and visuospatial-Benton's visual retention test (BVRT) and Block assembly test from Wechsler Adult Intelligence Scale BAT-functions, as well as for intensity of obsessive-compulsive symptoms (Yale Brown Obsessive Compulsive Scale, Y-BOCS). Correlation analysis was performed between neuropsychological performance, dystonia characteristics (duration, age of onset) and severity (Unified Dystonia Rating Scale, UDRS), and Y-BOCS. Patients made more perseverative errors on the WCST (P = 0.042) and had a higher mean Y-BOCS (P = 0.003) score than controls. Timed tests (BVRT, BAT, Stroop test) correlated with UDRS. Y-BOCS, WCST, and UDRS scores were not significantly correlated with one another.These results suggest that patients with primary dystonia may have set-shifting deficits and a higher intensity of obsessive compulsive symptoms when compared to healthy subjects. This may reflect a pattern of complex neurophysiological dysfunction involving dorsolateral, orbitofrontal, and motor frontostriatal circuits.</div></front></TEI></INIST><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Set‐shifting and behavioral dysfunction in primary focal dystonia</title><author><name sortKey="Bugalho, Paulo" sort="Bugalho, Paulo" uniqKey="Bugalho P" first="Paulo" last="Bugalho">Paulo Bugalho</name></author><author><name sortKey="Correa, Bernardo" sort="Correa, Bernardo" uniqKey="Correa B" first="Bernardo" last="Corrêa">Bernardo Corrêa</name></author><author><name sortKey="Guimaraes, Joao" sort="Guimaraes, Joao" uniqKey="Guimaraes J" first="João" last="Guimarães">João Guimarães</name></author><author><name sortKey="Xavier, Miguel" sort="Xavier, Miguel" uniqKey="Xavier M" first="Miguel" last="Xavier">Miguel Xavier</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0D92C89C99720074C60D8B7075AB71C3EA5F1DEC</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1002/mds.21784</idno><idno type="url">https://api.istex.fr/document/0D92C89C99720074C60D8B7075AB71C3EA5F1DEC/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001910</idno><idno type="wicri:Area/Istex/Curation">001910</idno><idno type="wicri:Area/Istex/Checkpoint">001188</idno><idno type="wicri:doubleKey">0885-3185:2008:Bugalho P:set:shifting:and</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:18044708</idno><idno type="wicri:Area/PubMed/Corpus">002424</idno><idno type="wicri:Area/PubMed/Curation">002424</idno><idno type="wicri:Area/PubMed/Checkpoint">002087</idno><idno type="wicri:Area/Ncbi/Merge">001F35</idno><idno type="wicri:Area/Ncbi/Curation">001F35</idno><idno type="wicri:Area/Ncbi/Checkpoint">001F35</idno><idno type="wicri:Area/Main/Merge">003210</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Set‐shifting and behavioral dysfunction in primary focal dystonia</title><author><name sortKey="Bugalho, Paulo" sort="Bugalho, Paulo" uniqKey="Bugalho P" first="Paulo" last="Bugalho">Paulo Bugalho</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Correa, Bernardo" sort="Correa, Bernardo" uniqKey="Correa B" first="Bernardo" last="Corrêa">Bernardo Corrêa</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Guimaraes, Joao" sort="Guimaraes, Joao" uniqKey="Guimaraes J" first="João" last="Guimarães">João Guimarães</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Neurology, Hospital Egas Moniz, Rua da Junqueira, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Xavier, Miguel" sort="Xavier, Miguel" uniqKey="Xavier M" first="Miguel" last="Xavier">Miguel Xavier</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Psychiatry and Mental Health, Hospital São Francisco Xavier, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-01-30">2008-01-30</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="200">200</biblScope><biblScope unit="page" to="206">206</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">0D92C89C99720074C60D8B7075AB71C3EA5F1DEC</idno><idno type="DOI">10.1002/mds.21784</idno><idno type="ArticleID">MDS21784</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Attention (physiology)</term><term>Behavioral Symptoms (etiology)</term><term>Dystonic Disorders (complications)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Set (Psychology)</term><term>Severity of Illness Index</term><term>executive dysfunction</term><term>frontostriatal circuits.</term><term>obsessive compulsive symptoms</term><term>primary dystonia</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Dystonic Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Behavioral Symptoms</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Attention</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Set (Psychology)</term><term>Severity of Illness Index</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The occurrence of cognitive and behavioral symptoms in patients with primary dystonia remains a matter of debate. We compared 45 patients with primary dystonia with 27 control subjects for performance on neuropsychological tasks with a load on executive‐Wisconsin Card Sorting Test (WCST) and Stroop test, and visuospatial‐Benton's visual retention test (BVRT) and Block assembly test from Wechsler Adult Intelligence Scale BAT‐functions, as well as for intensity of obsessive‐compulsive symptoms (Yale Brown Obsessive Compulsive Scale, Y‐BOCS). Correlation analysis was performed between neuropsychological performance, dystonia characteristics (duration, age of onset) and severity (Unified Dystonia Rating Scale, UDRS), and Y‐BOCS. Patients made more perseverative errors on the WCST (P = 0.042) and had a higher mean Y‐BOCS (P = 0.003) score than controls. Timed tests (BVRT, BAT, Stroop test) correlated with UDRS. Y‐BOCS, WCST, and UDRS scores were not significantly correlated with one another.These results suggest that patients with primary dystonia may have set‐shifting deficits and a higher intensity of obsessive compulsive symptoms when compared to healthy subjects. This may reflect a pattern of complex neurophysiological dysfunction involving dorsolateral, orbitofrontal, and motor frontostriatal circuits. © 2007 Movement Disorder Society</div></front></TEI></ISTEX></double></record>Pour manipuler ce document sous Unix (Dilib)
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