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Multivariable analysis of risk factors for enlargement of the tracheoesophageal puncture after total laryngectomy

Identifieur interne : 004750 ( Main/Merge ); précédent : 004749; suivant : 004751

Multivariable analysis of risk factors for enlargement of the tracheoesophageal puncture after total laryngectomy

Auteurs : Katherine A. Hutcheson [États-Unis] ; Jan S. Lewin [États-Unis] ; Erich M. Sturgis [États-Unis] ; Jan Risser [États-Unis]

Source :

RBID : ISTEX:0390BCBD18CC57BB3DCDA935E0FA3537BDF1FBEE

Abstract

Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high‐risk individuals, and surgical and prosthetic correlates of TEP enlargement.

Url:
DOI: 10.1002/hed.21777

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ISTEX:0390BCBD18CC57BB3DCDA935E0FA3537BDF1FBEE

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<sec id="S1">
<title>Background</title>
<p id="P1">Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high risk individuals, as well as surgical and prosthetic correlates of TEP enlargement.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5-year retrospective cohort.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow-up and timing of TEP, advanced (N2 or N3) nodal disease (OR
<sub>adjusted</sub>
: 4.3, 95% CI: 1.0-19.1), postoperative stricture (OR
<sub>adjusted</sub>
: 3.2, 95% CI: 1.2-8.6), and diagnosis of locoregional recurrence or distant metastasis after laryngectomy (OR
<sub>adjusted</sub>
: 6.2, 95% CI: 2.3-16.4) increased risk of enlarged TEP. Extended resection and preoperative nutritional status were also significantly associated with enlarged TEP. Prosthetic parameters did not significantly correlate with enlargement.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors.</p>
</sec>
</div>
</front>
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