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Multivariable analysis of risk factors for enlargement of the tracheoesophageal puncture after total laryngectomy

Identifieur interne : 000172 ( Istex/Corpus ); précédent : 000171; suivant : 000173

Multivariable analysis of risk factors for enlargement of the tracheoesophageal puncture after total laryngectomy

Auteurs : Katherine A. Hutcheson ; Jan S. Lewin ; Erich M. Sturgis ; Jan Risser

Source :

RBID : ISTEX:0390BCBD18CC57BB3DCDA935E0FA3537BDF1FBEE

Abstract

Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high‐risk individuals, and surgical and prosthetic correlates of TEP enlargement.

Url:
DOI: 10.1002/hed.21777

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ISTEX:0390BCBD18CC57BB3DCDA935E0FA3537BDF1FBEE

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Background
<p>Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high‐risk individuals, and surgical and prosthetic correlates of TEP enlargement.</p>
Methods
<p>Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5‐year retrospective cohort.</p>
Results
<p>Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow‐up and timing of TEP, advanced (N2 or N3) nodal disease (odds ratio [OR]
<hi rend="subscript">adjusted</hi>
, 4.3; 95% confidence interval [CI], 1.0–19.1), postoperative stricture (OR
<hi rend="subscript">adjusted</hi>
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<hi rend="subscript">adjusted</hi>
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Conclusion
<p>Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors. © 2011 Wiley Periodicals, Inc. Head Neck, 2012</p>
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<keyword xml:id="kwd1">tracheoesophageal puncture</keyword>
<keyword xml:id="kwd2">total laryngectomy</keyword>
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<p>Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high‐risk individuals, and surgical and prosthetic correlates of TEP enlargement.</p>
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<p>Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5‐year retrospective cohort.</p>
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<title type="main">Results</title>
<p>Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow‐up and timing of TEP, advanced (N2 or N3) nodal disease (odds ratio [OR]
<sub>adjusted</sub>
, 4.3; 95% confidence interval [CI], 1.0–19.1), postoperative stricture (OR
<sub>adjusted</sub>
, 3.2; 95% CI, 1.2–8.6), and diagnosis of locoregional recurrence or distant metastasis after laryngectomy (OR
<sub>adjusted</sub>
, 6.2; 95% CI, 2.3–16.4) increased risk of enlarged TEP. Extended resection and preoperative nutritional status were also significantly associated with enlarged TEP. Prosthetic parameters did not significantly correlate with enlargement.</p>
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<title type="main">Conclusion</title>
<p>Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors. © 2011 Wiley Periodicals, Inc. Head Neck, 2012</p>
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<affiliation>Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas</affiliation>
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<abstract>Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high‐risk individuals, and surgical and prosthetic correlates of TEP enlargement.</abstract>
<abstract>Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5‐year retrospective cohort.</abstract>
<abstract>Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow‐up and timing of TEP, advanced (N2 or N3) nodal disease (odds ratio [OR]adjusted, 4.3; 95% confidence interval [CI], 1.0–19.1), postoperative stricture (ORadjusted, 3.2; 95% CI, 1.2–8.6), and diagnosis of locoregional recurrence or distant metastasis after laryngectomy (ORadjusted, 6.2; 95% CI, 2.3–16.4) increased risk of enlarged TEP. Extended resection and preoperative nutritional status were also significantly associated with enlarged TEP. Prosthetic parameters did not significantly correlate with enlargement.</abstract>
<abstract>Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors. © 2011 Wiley Periodicals, Inc. Head Neck, 2012</abstract>
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