Multivariable Analysis of Risk Factors for Enlargement of the Tracheoesophageal Puncture After Total Laryngectomy
Identifieur interne : 004455 ( Ncbi/Checkpoint ); précédent : 004454; suivant : 004456Multivariable Analysis of Risk Factors for Enlargement of the Tracheoesophageal Puncture After Total Laryngectomy
Auteurs : Katherine A. Hutcheson [États-Unis] ; Jan S. Lewin [États-Unis] ; Erich M. Sturgis [États-Unis] ; Jan Risser [États-Unis]Source :
- Head & neck [ 1043-3074 ] ; 2011.
Abstract
Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high risk individuals, as well as surgical and prosthetic correlates of TEP enlargement.
Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5-year retrospective cohort.
Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow-up and timing of TEP, advanced (N2 or N3) nodal disease (ORadjusted: 4.3, 95% CI: 1.0-19.1), postoperative stricture (ORadjusted: 3.2, 95% CI: 1.2-8.6), and diagnosis of locoregional recurrence or distant metastasis after laryngectomy (ORadjusted: 6.2, 95% CI: 2.3-16.4) increased risk of enlarged TEP. Extended resection and preoperative nutritional status were also significantly associated with enlarged TEP. Prosthetic parameters did not significantly correlate with enlargement.
Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors.
Url:
DOI: 10.1002/hed.21777
PubMed: 21692129
PubMed Central: 4012756
Affiliations:
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<author><name sortKey="Hutcheson, Katherine A" sort="Hutcheson, Katherine A" uniqKey="Hutcheson K" first="Katherine A." last="Hutcheson">Katherine A. Hutcheson</name>
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<author><name sortKey="Lewin, Jan S" sort="Lewin, Jan S" uniqKey="Lewin J" first="Jan S." last="Lewin">Jan S. Lewin</name>
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<series><title level="j">Head & neck</title>
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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Enlarged tracheoesophageal puncture (TEP) is a challenging complication of surgical prosthetic voice restoration. Prevention of this complication requires identification of high risk individuals, as well as surgical and prosthetic correlates of TEP enlargement.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Multivariable logistic regression methods were used to analyze preoperative, perioperative, and postoperative risk factors for enlarged TEP in a 5-year retrospective cohort.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Enlarged TEP only occurred in irradiated patients. Adjusting for length of follow-up and timing of TEP, advanced (N2 or N3) nodal disease (OR<sub>adjusted</sub>
: 4.3, 95% CI: 1.0-19.1), postoperative stricture (OR<sub>adjusted</sub>
: 3.2, 95% CI: 1.2-8.6), and diagnosis of locoregional recurrence or distant metastasis after laryngectomy (OR<sub>adjusted</sub>
: 6.2, 95% CI: 2.3-16.4) increased risk of enlarged TEP. Extended resection and preoperative nutritional status were also significantly associated with enlarged TEP. Prosthetic parameters did not significantly correlate with enlargement.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Development of enlarged TEP is a multifactorial process related to both baseline and postoperative factors.</p>
</sec>
</div>
</front>
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<region><li>Texas</li>
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<name sortKey="Lewin, Jan S" sort="Lewin, Jan S" uniqKey="Lewin J" first="Jan S." last="Lewin">Jan S. Lewin</name>
<name sortKey="Risser, Jan" sort="Risser, Jan" uniqKey="Risser J" first="Jan" last="Risser">Jan Risser</name>
<name sortKey="Sturgis, Erich M" sort="Sturgis, Erich M" uniqKey="Sturgis E" first="Erich M." last="Sturgis">Erich M. Sturgis</name>
<name sortKey="Sturgis, Erich M" sort="Sturgis, Erich M" uniqKey="Sturgis E" first="Erich M." last="Sturgis">Erich M. Sturgis</name>
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