LymphedemaV1, Main, Curation, bibRecord, 00BB03

Evidence for altered cell‐mediated immunity in postmastectomy lymphoedema

Identifieur interne : 00BB03 ( Main/Curation ); précédent : 00BB02; suivant : 00BB04

Evidence for altered cell‐mediated immunity in postmastectomy lymphoedema

Auteurs : E. Mallon [Royaume-Uni] ; S. Powell [Royaume-Uni] ; Peter Mortimer (dermatologue)‎ [Royaume-Uni] ; T. J. Ryan [Royaume-Uni]

Source :

British Journal of Dermatology [ 0007-0963 ] ; 1997-12.

RBID : ISTEX:0E49BBE30841A93A8BB3BB5932CCF9E6B87079FE

Descripteurs français

KwdFr :
- 1-Chloro-2,4-dinitro-benzène (immunologie), Adulte, Adulte d'âge moyen, Eczéma de contact allergique (immunologie), Femelle, Humains, Immunité cellulaire, Immunocompétence, Lymphoedème (immunologie), Lymphoedème (étiologie), Mastectomie (effets indésirables), Relation dose-réponse (immunologie), Sujet âgé, Tests épicutanés, Tumeurs du sein ().
MESH :
- effets indésirables : Mastectomie.
- immunologie : 1-Chloro-2,4-dinitro-benzène, Eczéma de contact allergique, Lymphoedème.
- étiologie : Lymphoedème.
Pascal (Inist)
- Adulte, Adulte d'âge moyen, Association, Femelle, Homme, Humains, Immunité cellulaire, Immunocompétence, Lymphoedème, Mastectomie, Peau, Relation dose-réponse (immunologie), Réponse immune, Sujet âgé, Tests épicutanés, Tumeurs du sein.
Wicri :
- topic : Association, Homme.

English descriptors

KwdEn :
- Adult, Aged, Association, Breast Neoplasms (surgery), Cellular immunity, Dermatitis, Allergic Contact (immunology), Dinitrochlorobenzene (immunology), Dose-Response Relationship, Immunologic, Female, Human, Humans, Immune response, Immunity, Cellular, Immunocompetence, Lymphedema, Lymphedema (etiology), Lymphedema (immunology), Mastectomy, Mastectomy (adverse effects), Middle Aged, Patch Tests, Skin.
MESH :
- chemical , immunology : Dinitrochlorobenzene.
- adverse effects : Mastectomy.
- etiology : Lymphedema.
- immunology : Dermatitis, Allergic Contact, Lymphedema.
- surgery : Breast Neoplasms.
- Adult, Aged, Dose-Response Relationship, Immunologic, Female, Humans, Immunity, Cellular, Immunocompetence, Middle Aged, Patch Tests.

Abstract

Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell‐mediated immunity is impaired. 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results suppot the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.

Url:

https://api.istex.fr/document/0E49BBE30841A93A8BB3BB5932CCF9E6B87079FE/fulltext/pdf

DOI: 10.1046/j.1365-2133.1997.19872068.x

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ISTEX:0E49BBE30841A93A8BB3BB5932CCF9E6B87079FE

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<front><div type="abstract" xml:lang="en">Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell‐mediated immunity is impaired. 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results suppot the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</div>
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<term>Mastectomy</term>
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<term>Association</term>
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<front><div type="abstract" xml:lang="en">Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</div>
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<author><name sortKey="Mortimer, P" sort="Mortimer, P" uniqKey="Mortimer P" first="P." last="Mortimer">Peter Mortimer (dermatologue)‎</name>
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<author><name sortKey="Ryan, T J" sort="Ryan, T J" uniqKey="Ryan T" first="T. J." last="Ryan">T. J. Ryan</name>
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<author><name sortKey="Mortimer, P" sort="Mortimer, P" uniqKey="Mortimer P" first="P." last="Mortimer">Peter Mortimer (dermatologue)‎</name>
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<front><div type="abstract" xml:lang="en">Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell‐mediated immunity is impaired. 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results suppot the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</div>
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<term>Dose-Response Relationship, Immunologic</term>
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<term>Immunity, Cellular</term>
<term>Immunocompetence</term>
<term>Lymphedema (etiology)</term>
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<term>Mastectomy (adverse effects)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>1-Chloro-2,4-dinitro-benzène (immunologie)</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Eczéma de contact allergique (immunologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Immunité cellulaire</term>
<term>Immunocompétence</term>
<term>Lymphoedème (immunologie)</term>
<term>Lymphoedème (étiologie)</term>
<term>Mastectomie (effets indésirables)</term>
<term>Relation dose-réponse (immunologie)</term>
<term>Sujet âgé</term>
<term>Tests épicutanés</term>
<term>Tumeurs du sein ()</term>
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<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Dinitrochlorobenzene</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Mastectomy</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>1-Chloro-2,4-dinitro-benzène</term>
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<front><div type="abstract" xml:lang="en">Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</div>
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Evidence for altered cell‐mediated immunity in postmastectomy lymphoedema

Evidence for altered cell‐mediated immunity in postmastectomy lymphoedema

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