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Evidence for altered cell-mediated immunity in postmastectomy lymphoedema

Identifieur interne : 000B15 ( PascalFrancis/Corpus ); précédent : 000B14; suivant : 000B16

Evidence for altered cell-mediated immunity in postmastectomy lymphoedema

Auteurs : E. Mallon ; S. Powell ; P. Mortimer ; T. J. Ryan

Source :

RBID : Pascal:98-0066833

Descripteurs français

English descriptors

Abstract

Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0007-0963
A02 01      @0 BJDEAZ
A03   1    @0 Br. j. dermatol. : (1951)
A05       @2 137
A06       @2 6
A08 01  1  ENG  @1 Evidence for altered cell-mediated immunity in postmastectomy lymphoedema
A11 01  1    @1 MALLON (E.)
A11 02  1    @1 POWELL (S.)
A11 03  1    @1 MORTIMER (P.)
A11 04  1    @1 RYAN (T. J.)
A14 01      @1 Department of Dermatology, Churchill Hospital @2 Oxford @3 GBR @Z 1 aut. @Z 2 aut. @Z 4 aut.
A14 02      @1 Department of Dermatology, St George's Hospital @2 London @3 GBR @Z 3 aut.
A20       @1 928-933
A21       @1 1997
A23 01      @0 ENG
A43 01      @1 INIST @2 1043 @5 354000079810390120
A44       @0 0000 @1 © 1998 INIST-CNRS. All rights reserved.
A45       @0 36 ref.
A47 01  1    @0 98-0066833
A60       @1 P
A61       @0 A
A64   1    @0 British journal of dermatology : (1951)
A66 01      @0 GBR
C01 01    ENG  @0 Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.
C02 01  X    @0 002B12B04
C03 01  X  FRE  @0 Mastectomie @5 01
C03 01  X  ENG  @0 Mastectomy @5 01
C03 01  X  SPA  @0 Mastectomía @5 01
C03 02  X  FRE  @0 Association @5 02
C03 02  X  ENG  @0 Association @5 02
C03 02  X  SPA  @0 Asociación @5 02
C03 03  X  FRE  @0 Lymphoedème @5 04
C03 03  X  ENG  @0 Lymphedema @5 04
C03 03  X  SPA  @0 Linfedema @5 04
C03 04  X  FRE  @0 Immunité cellulaire @5 05
C03 04  X  ENG  @0 Cellular immunity @5 05
C03 04  X  SPA  @0 Inmunidad celular @5 05
C03 05  X  FRE  @0 Peau @5 06
C03 05  X  ENG  @0 Skin @5 06
C03 05  X  SPA  @0 Piel @5 06
C03 06  X  FRE  @0 Réponse immune @5 07
C03 06  X  ENG  @0 Immune response @5 07
C03 06  X  SPA  @0 Respuesta inmune @5 07
C03 07  X  FRE  @0 Homme @5 08
C03 07  X  ENG  @0 Human @5 08
C03 07  X  SPA  @0 Hombre @5 08
C07 01  X  FRE  @0 Peau pathologie @5 37
C07 01  X  ENG  @0 Skin disease @5 37
C07 01  X  SPA  @0 Piel patología @5 37
C07 02  X  FRE  @0 Appareil circulatoire pathologie @5 45
C07 02  X  ENG  @0 Cardiovascular disease @5 45
C07 02  X  SPA  @0 Aparato circulatorio patología @5 45
C07 03  X  FRE  @0 Lymphatique pathologie @5 46
C07 03  X  ENG  @0 Lymphatic vessel disease @5 46
C07 03  X  SPA  @0 Linfático patología @5 46
N21       @1 040

Format Inist (serveur)

NO : PASCAL 98-0066833 INIST
ET : Evidence for altered cell-mediated immunity in postmastectomy lymphoedema
AU : MALLON (E.); POWELL (S.); MORTIMER (P.); RYAN (T. J.)
AF : Department of Dermatology, Churchill Hospital/Oxford/Royaume-Uni (1 aut., 2 aut., 4 aut.); Department of Dermatology, St George's Hospital/London/Royaume-Uni (3 aut.)
DT : Publication en série; Niveau analytique
SO : British journal of dermatology : (1951); ISSN 0007-0963; Coden BJDEAZ; Royaume-Uni; Da. 1997; Vol. 137; No. 6; Pp. 928-933; Bibl. 36 ref.
LA : Anglais
EA : Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.
CC : 002B12B04
FD : Mastectomie; Association; Lymphoedème; Immunité cellulaire; Peau; Réponse immune; Homme
FG : Peau pathologie; Appareil circulatoire pathologie; Lymphatique pathologie
ED : Mastectomy; Association; Lymphedema; Cellular immunity; Skin; Immune response; Human
EG : Skin disease; Cardiovascular disease; Lymphatic vessel disease
SD : Mastectomía; Asociación; Linfedema; Inmunidad celular; Piel; Respuesta inmune; Hombre
LO : INIST-1043.354000079810390120
ID : 98-0066833

Links to Exploration step

Pascal:98-0066833

Le document en format XML

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<ET>Evidence for altered cell-mediated immunity in postmastectomy lymphoedema</ET>
<AU>MALLON (E.); POWELL (S.); MORTIMER (P.); RYAN (T. J.)</AU>
<AF>Department of Dermatology, Churchill Hospital/Oxford/Royaume-Uni (1 aut., 2 aut., 4 aut.); Department of Dermatology, St George's Hospital/London/Royaume-Uni (3 aut.)</AF>
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<EA>Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</EA>
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