LymphedemaV1, PubMed, Corpus, bibRecord, 004F35

Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.

Identifieur interne : 004F35 ( PubMed/Corpus ); précédent : 004F34; suivant : 004F36

Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.

Auteurs : E. Mallon ; S. Powell ; P. Mortimer ; T J Ryan

Source :

The British journal of dermatology [ 0007-0963 ] ; 1997.

RBID : pubmed:9470909

English descriptors

KwdEn :
- Adult, Aged, Breast Neoplasms (surgery), Dermatitis, Allergic Contact (immunology), Dinitrochlorobenzene (immunology), Dose-Response Relationship, Immunologic, Female, Humans, Immunity, Cellular, Immunocompetence, Lymphedema (etiology), Lymphedema (immunology), Mastectomy (adverse effects), Middle Aged, Patch Tests.
MESH :
- chemical , immunology : Dinitrochlorobenzene.
- adverse effects : Mastectomy.
- etiology : Lymphedema.
- immunology : Dermatitis, Allergic Contact, Lymphedema.
- surgery : Breast Neoplasms.
- Adult, Aged, Dose-Response Relationship, Immunologic, Female, Humans, Immunity, Cellular, Immunocompetence, Middle Aged, Patch Tests.

Abstract

Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.

PubMed: 9470909

Links to Exploration step

pubmed:9470909

Le document en format XML

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<author><name sortKey="Mallon, E" sort="Mallon, E" uniqKey="Mallon E" first="E" last="Mallon">E. Mallon</name>
<affiliation><nlm:affiliation>Department of Dermatology, Churchill Hospital, Oxford, U.K.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Powell, S" sort="Powell, S" uniqKey="Powell S" first="S" last="Powell">S. Powell</name>
</author>
<author><name sortKey="Mortimer, P" sort="Mortimer, P" uniqKey="Mortimer P" first="P" last="Mortimer">P. Mortimer</name>
</author>
<author><name sortKey="Ryan, T J" sort="Ryan, T J" uniqKey="Ryan T" first="T J" last="Ryan">T J Ryan</name>
</author>
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<date when="1997">1997</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.</title>
<author><name sortKey="Mallon, E" sort="Mallon, E" uniqKey="Mallon E" first="E" last="Mallon">E. Mallon</name>
<affiliation><nlm:affiliation>Department of Dermatology, Churchill Hospital, Oxford, U.K.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Powell, S" sort="Powell, S" uniqKey="Powell S" first="S" last="Powell">S. Powell</name>
</author>
<author><name sortKey="Mortimer, P" sort="Mortimer, P" uniqKey="Mortimer P" first="P" last="Mortimer">P. Mortimer</name>
</author>
<author><name sortKey="Ryan, T J" sort="Ryan, T J" uniqKey="Ryan T" first="T J" last="Ryan">T J Ryan</name>
</author>
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<series><title level="j">The British journal of dermatology</title>
<idno type="ISSN">0007-0963</idno>
<imprint><date when="1997" type="published">1997</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Breast Neoplasms (surgery)</term>
<term>Dermatitis, Allergic Contact (immunology)</term>
<term>Dinitrochlorobenzene (immunology)</term>
<term>Dose-Response Relationship, Immunologic</term>
<term>Female</term>
<term>Humans</term>
<term>Immunity, Cellular</term>
<term>Immunocompetence</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (immunology)</term>
<term>Mastectomy (adverse effects)</term>
<term>Middle Aged</term>
<term>Patch Tests</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Dinitrochlorobenzene</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Mastectomy</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Dermatitis, Allergic Contact</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Dose-Response Relationship, Immunologic</term>
<term>Female</term>
<term>Humans</term>
<term>Immunity, Cellular</term>
<term>Immunocompetence</term>
<term>Middle Aged</term>
<term>Patch Tests</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9470909</PMID>
<DateCreated><Year>1998</Year>
<Month>02</Month>
<Day>23</Day>
</DateCreated>
<DateCompleted><Year>1998</Year>
<Month>02</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0007-0963</ISSN>
<JournalIssue CitedMedium="Print"><Volume>137</Volume>
<Issue>6</Issue>
<PubDate><Year>1997</Year>
<Month>Dec</Month>
</PubDate>
</JournalIssue>
<Title>The British journal of dermatology</Title>
<ISOAbbreviation>Br. J. Dermatol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.</ArticleTitle>
<Pagination><MedlinePgn>928-33</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Patients with chronic lymphoedema are prone to develop chronic infections and various tumours in the lymphoedematous limb, suggesting that regional immune surveillance is impaired. To test the hypothesis that cutaneous cell-mediated immunity is impaired, 35 women with postmastectomy lymphoedema were investigated using dinitrochlorobenzene to test the afferent and efferent loops of the allergic contact immune response. The results support the role of lymphatics as an important component of the immune response to allergens by the demonstration of impairment of both the afferent and efferent loops of the allergic contact dermatitis reaction, and confirm that there is suppression of immune competence in a lymphoedematous limb.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mallon</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Dermatology, Churchill Hospital, Oxford, U.K.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Powell</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Mortimer</LastName>
<ForeName>P</ForeName>
<Initials>P</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ryan</LastName>
<ForeName>T J</ForeName>
<Initials>TJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType>
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<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Br J Dermatol</MedlineTA>
<NlmUniqueID>0004041</NlmUniqueID>
<ISSNLinking>0007-0963</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>GE3IBT7BMN</RegistryNumber>
<NameOfSubstance UI="D004137">Dinitrochlorobenzene</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017449" MajorTopicYN="N">Dermatitis, Allergic Contact</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004137" MajorTopicYN="N">Dinitrochlorobenzene</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004306" MajorTopicYN="N">Dose-Response Relationship, Immunologic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007111" MajorTopicYN="N">Immunity, Cellular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007121" MajorTopicYN="Y">Immunocompetence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008408" MajorTopicYN="N">Mastectomy</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010328" MajorTopicYN="N">Patch Tests</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1998</Year>
<Month>2</Month>
<Day>21</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1998</Year>
<Month>2</Month>
<Day>21</Day>
<Hour>0</Hour>
<Minute>1</Minute>
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<PubMedPubDate PubStatus="entrez"><Year>1998</Year>
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<Minute>0</Minute>
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</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">9470909</ArticleId>
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Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.

Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki