The Use of Antimalarial Drugs against Viral Infection
Identifieur interne : 000027 ( Main/Exploration ); précédent : 000026; suivant : 000028The Use of Antimalarial Drugs against Viral Infection
Auteurs : Sarah D Lessandro ; Diletta Scaccabarozzi ; Lucia Signorini ; Federica Perego ; Denise P. Ilboudo ; Pasquale Ferrante ; Serena DelbueSource :
- Microorganisms [ 2076-2607 ] ; 2020.
Abstract
In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.
Url:
DOI: 10.3390/microorganisms8010085
PubMed: 31936284
PubMed Central: 7022795
Affiliations:
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Le document en format XML
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<author><name sortKey="Signorini, Lucia" sort="Signorini, Lucia" uniqKey="Signorini L" first="Lucia" last="Signorini">Lucia Signorini</name>
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<author><name sortKey="Delbue, Serena" sort="Delbue, Serena" uniqKey="Delbue S" first="Serena" last="Delbue">Serena Delbue</name>
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<affiliation><nlm:aff id="af1-microorganisms-08-00085">Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy;<email>sarah.dalessandro@unimi.it</email>
(S.D.);<email>lucia.signorini@unimi.it</email>
(L.S.);<email>federica.perego@unimi.it</email>
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<author><name sortKey="Scaccabarozzi, Diletta" sort="Scaccabarozzi, Diletta" uniqKey="Scaccabarozzi D" first="Diletta" last="Scaccabarozzi">Diletta Scaccabarozzi</name>
<affiliation><nlm:aff id="af2-microorganisms-08-00085">Department of Pharmacological and Biomolecular Sciences, University of Milano, 20133 Milan, Italy;<email>diletta.scaccabarozzi@unimi.it</email>
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<author><name sortKey="Signorini, Lucia" sort="Signorini, Lucia" uniqKey="Signorini L" first="Lucia" last="Signorini">Lucia Signorini</name>
<affiliation><nlm:aff id="af1-microorganisms-08-00085">Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy;<email>sarah.dalessandro@unimi.it</email>
(S.D.);<email>lucia.signorini@unimi.it</email>
(L.S.);<email>federica.perego@unimi.it</email>
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<author><name sortKey="Perego, Federica" sort="Perego, Federica" uniqKey="Perego F" first="Federica" last="Perego">Federica Perego</name>
<affiliation><nlm:aff id="af1-microorganisms-08-00085">Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy;<email>sarah.dalessandro@unimi.it</email>
(S.D.);<email>lucia.signorini@unimi.it</email>
(L.S.);<email>federica.perego@unimi.it</email>
(F.P.);<email>pasquale.ferrante@unimi.it</email>
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<author><name sortKey="Ilboudo, Denise P" sort="Ilboudo, Denise P" uniqKey="Ilboudo D" first="Denise P." last="Ilboudo">Denise P. Ilboudo</name>
<affiliation><nlm:aff id="af3-microorganisms-08-00085">Département des Sciences de la Vie, University of Fada N’Gourma (UFDG), Fada N’Gourma BP 54, Burkina Faso;<email>denise.ilboudo@gmail.com</email>
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<author><name sortKey="Ferrante, Pasquale" sort="Ferrante, Pasquale" uniqKey="Ferrante P" first="Pasquale" last="Ferrante">Pasquale Ferrante</name>
<affiliation><nlm:aff id="af1-microorganisms-08-00085">Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy;<email>sarah.dalessandro@unimi.it</email>
(S.D.);<email>lucia.signorini@unimi.it</email>
(L.S.);<email>federica.perego@unimi.it</email>
(F.P.);<email>pasquale.ferrante@unimi.it</email>
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<author><name sortKey="Delbue, Serena" sort="Delbue, Serena" uniqKey="Delbue S" first="Serena" last="Delbue">Serena Delbue</name>
<affiliation><nlm:aff id="af1-microorganisms-08-00085">Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy;<email>sarah.dalessandro@unimi.it</email>
(S.D.);<email>lucia.signorini@unimi.it</email>
(L.S.);<email>federica.perego@unimi.it</email>
(F.P.);<email>pasquale.ferrante@unimi.it</email>
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<front><div type="abstract" xml:lang="en"><p>In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.</p>
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<tree><noCountry><name sortKey="D Lessandro, Sarah" sort="D Lessandro, Sarah" uniqKey="D Lessandro S" first="Sarah" last="D Lessandro">Sarah D Lessandro</name>
<name sortKey="Delbue, Serena" sort="Delbue, Serena" uniqKey="Delbue S" first="Serena" last="Delbue">Serena Delbue</name>
<name sortKey="Ferrante, Pasquale" sort="Ferrante, Pasquale" uniqKey="Ferrante P" first="Pasquale" last="Ferrante">Pasquale Ferrante</name>
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