Somatostatin in eating disorders
Identifieur interne : 002A82 ( Main/Exploration ); précédent : 002A81; suivant : 002A83Somatostatin in eating disorders
Auteurs : Karl M. Pirke [Allemagne] ; Elisabeth Frie [Allemagne] ; Michael B. Kellner [Allemagne] ; Jürgen-C. Krieg [Allemagne] ; Manfred M. Fichter [Allemagne]Source :
- International Journal of Eating Disorders [ 0276-3478 ] ; 1994-01.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Femme.
English descriptors
- KwdEn :
- Adult, Anorexia Nervosa (blood), Anorexia Nervosa (diagnosis), Anorexia nervosa, Eating disorder, Endocrine secretion, Energy Intake, Female, Hormonal investigation, Humans, Insulin (blood), Neuropeptide, Obesity, Obesity (blood), Obesity (diagnosis), Psychiatric Status Rating Scales, Radioimmunoassay, Somatostatin, Somatostatin (blood), Woman.
- MESH :
- chemical , blood : Insulin, Somatostatin.
- blood : Anorexia Nervosa, Obesity.
- diagnosis : Anorexia Nervosa, Obesity.
- Adult, Energy Intake, Female, Humans, Psychiatric Status Rating Scales, Radioimmunoassay.
Abstract
Somatostatin concentrations in plasma were measured before and after a standardized fat and protein‐rich fluid test meal in patients with anorexia nervosa, weight‐recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.
Url:
DOI: 10.1002/1098-108X(199401)15:1<99::AID-EAT2260150112>3.0.CO;2-X
Affiliations:
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Le document en format XML
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<term>Anorexia nervosa</term>
<term>Eating disorder</term>
<term>Endocrine secretion</term>
<term>Energy Intake</term>
<term>Female</term>
<term>Hormonal investigation</term>
<term>Humans</term>
<term>Insulin (blood)</term>
<term>Neuropeptide</term>
<term>Obesity</term>
<term>Obesity (blood)</term>
<term>Obesity (diagnosis)</term>
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<term>Radioimmunoassay</term>
<term>Somatostatin</term>
<term>Somatostatin (blood)</term>
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<term>Psychiatric Status Rating Scales</term>
<term>Radioimmunoassay</term>
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<term>Obésité</term>
<term>Somatostatine</term>
<term>Sécrétion endocrine</term>
<term>Trouble comportement alimentaire</term>
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<front><div type="abstract" xml:lang="en">Somatostatin concentrations in plasma were measured before and after a standardized fat and protein‐rich fluid test meal in patients with anorexia nervosa, weight‐recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.</div>
</front>
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<name sortKey="Krieg, Jurgen" sort="Krieg, Jurgen" uniqKey="Krieg J" first="Jürgen-C." last="Krieg">Jürgen-C. Krieg</name>
<name sortKey="Pirke, Karl M" sort="Pirke, Karl M" uniqKey="Pirke K" first="Karl M." last="Pirke">Karl M. Pirke</name>
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