UnivTrevesV1, Ncbi, Checkpoint, bibRecord, 000A80

Somatostatin in eating disorders.

Identifieur interne : 000A80 ( Ncbi/Checkpoint ); précédent : 000A79; suivant : 000A81

Somatostatin in eating disorders.

Auteurs : K M Pirke [Allemagne] ; E. Friess ; M B Kellner ; J C Krieg ; M M Fichter

Source :

The International journal of eating disorders [ 0276-3478 ] ; 1994.

RBID : pubmed:7907255

English descriptors

KwdEn :
- Adult, Anorexia Nervosa (blood), Anorexia Nervosa (diagnosis), Energy Intake, Female, Humans, Insulin (blood), Obesity (blood), Obesity (diagnosis), Psychiatric Status Rating Scales, Radioimmunoassay, Somatostatin (blood).
MESH :
- chemical , blood : Insulin, Somatostatin.
- blood : Anorexia Nervosa, Obesity.
- diagnosis : Anorexia Nervosa, Obesity.
- Adult, Energy Intake, Female, Humans, Psychiatric Status Rating Scales, Radioimmunoassay.

Abstract

Somatostatin concentrations in plasma were measured before and after a standardized fat and protein-rich fluid test meal in patients with anorexia nervosa, weight-recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight-recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders.

PubMed: 7907255

Affiliations:

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pubmed:7907255

Le document en format XML

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<author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychoendocrinology, University of Trier, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychoendocrinology, University of Trier</wicri:regionArea>
<placeName><settlement type="city">Trèves (Allemagne)</settlement>
<region type="land" nuts="1">Rhénanie-Palatinat</region>
</placeName>
<orgName type="university">Université de Trèves</orgName>
</affiliation>
</author>
<author><name sortKey="Friess, E" sort="Friess, E" uniqKey="Friess E" first="E" last="Friess">E. Friess</name>
</author>
<author><name sortKey="Kellner, M B" sort="Kellner, M B" uniqKey="Kellner M" first="M B" last="Kellner">M B Kellner</name>
</author>
<author><name sortKey="Krieg, J C" sort="Krieg, J C" uniqKey="Krieg J" first="J C" last="Krieg">J C Krieg</name>
</author>
<author><name sortKey="Fichter, M M" sort="Fichter, M M" uniqKey="Fichter M" first="M M" last="Fichter">M M Fichter</name>
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<date when="1994">1994</date>
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<author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychoendocrinology, University of Trier, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychoendocrinology, University of Trier</wicri:regionArea>
<placeName><settlement type="city">Trèves (Allemagne)</settlement>
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<author><name sortKey="Friess, E" sort="Friess, E" uniqKey="Friess E" first="E" last="Friess">E. Friess</name>
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<author><name sortKey="Kellner, M B" sort="Kellner, M B" uniqKey="Kellner M" first="M B" last="Kellner">M B Kellner</name>
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<author><name sortKey="Krieg, J C" sort="Krieg, J C" uniqKey="Krieg J" first="J C" last="Krieg">J C Krieg</name>
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<series><title level="j">The International journal of eating disorders</title>
<idno type="ISSN">0276-3478</idno>
<imprint><date when="1994" type="published">1994</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
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<term>Anorexia Nervosa (diagnosis)</term>
<term>Energy Intake</term>
<term>Female</term>
<term>Humans</term>
<term>Insulin (blood)</term>
<term>Obesity (blood)</term>
<term>Obesity (diagnosis)</term>
<term>Psychiatric Status Rating Scales</term>
<term>Radioimmunoassay</term>
<term>Somatostatin (blood)</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Insulin</term>
<term>Somatostatin</term>
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<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Anorexia Nervosa</term>
<term>Obesity</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Anorexia Nervosa</term>
<term>Obesity</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Energy Intake</term>
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<term>Humans</term>
<term>Psychiatric Status Rating Scales</term>
<term>Radioimmunoassay</term>
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<front><div type="abstract" xml:lang="en">Somatostatin concentrations in plasma were measured before and after a standardized fat and protein-rich fluid test meal in patients with anorexia nervosa, weight-recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight-recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders.</div>
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<tree><noCountry><name sortKey="Fichter, M M" sort="Fichter, M M" uniqKey="Fichter M" first="M M" last="Fichter">M M Fichter</name>
<name sortKey="Friess, E" sort="Friess, E" uniqKey="Friess E" first="E" last="Friess">E. Friess</name>
<name sortKey="Kellner, M B" sort="Kellner, M B" uniqKey="Kellner M" first="M B" last="Kellner">M B Kellner</name>
<name sortKey="Krieg, J C" sort="Krieg, J C" uniqKey="Krieg J" first="J C" last="Krieg">J C Krieg</name>
</noCountry>
<country name="Allemagne"><region name="Rhénanie-Palatinat"><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
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</record>

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Somatostatin in eating disorders.

Somatostatin in eating disorders.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki