Somatostatin in eating disorders
Identifieur interne : 000633 ( Istex/Corpus ); précédent : 000632; suivant : 000634Somatostatin in eating disorders
Auteurs : Karl M. Pirke ; Elisabeth Frie ; Michael B. Kellner ; Jürgen-C. Krieg ; Manfred M. FichterSource :
- International Journal of Eating Disorders [ 0276-3478 ] ; 1994-01.
Abstract
Somatostatin concentrations in plasma were measured before and after a standardized fat and protein‐rich fluid test meal in patients with anorexia nervosa, weight‐recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.
Url:
DOI: 10.1002/1098-108X(199401)15:1<99::AID-EAT2260150112>3.0.CO;2-X
Links to Exploration step
ISTEX:3C153FBF4D802C29BCF9A3FC5CDF9172BA316206Le document en format XML
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Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Karl M. 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The area under the response curve was significantly higher (p > .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.</abstract><qualityIndicators><score>2.687</score><pdfVersion>1.3</pdfVersion><pdfPageSize>504 x 720 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>759</abstractCharCount><pdfWordCount>1343</pdfWordCount><pdfCharCount>8821</pdfCharCount><pdfPageCount>4</pdfPageCount><abstractWordCount>112</abstractWordCount></qualityIndicators><title>Somatostatin in eating disorders</title><refBibs><json:item><author><json:item><name>T. Barreca</name></json:item><json:item><name>R. Franceschini</name></json:item><json:item><name>V. Messina</name></json:item><json:item><name>A. Cataldi</name></json:item><json:item><name>M. Salvemini</name></json:item><json:item><name>E. Rolandi</name></json:item></author><host><volume>31</volume><pages><last>237</last><first>234</first></pages><author></author><title>Hormone Research</title></host><title>Plasma somato‐statin and vasoactive intestinal polypeptide responses to an oral mixed test meal in obese patients</title></json:item><json:item><author><json:item><name>E. Bonora</name></json:item><json:item><name>P. Moghetti</name></json:item><json:item><name>C. Zancanaro</name></json:item><json:item><name>M. Cigolini</name></json:item><json:item><name>M. Querena</name></json:item><json:item><name>V. Cacciatori</name></json:item><json:item><name>M. Zenere</name></json:item><json:item><name>A. Corgnati</name></json:item><json:item><name>M. Muggeo</name></json:item></author><host><volume>22</volume><pages><last>588</last><first>584</first></pages><author></author><title>Hormone Metabolism Research</title></host><title>Normal inhibition by somatostatin of glucose‐stimulated B cell secretion in the obese subjects</title></json:item><json:item><author><json:item><name>R. Carretta</name></json:item><json:item><name>B. Fabris</name></json:item><json:item><name>F. Fischetti</name></json:item><json:item><name>M. Costantini</name></json:item><json:item><name>F. De Biasi</name></json:item><json:item><name>S. Muiesan</name></json:item><json:item><name>M. Bardelli</name></json:item><json:item><name>F. Vran</name></json:item><json:item><name>L. Campanacci</name></json:item></author><host><volume>7</volume><pages><last>197</last><first>196</first></pages><issue>Suppl.</issue><author></author><title>Journal Hypertension</title></host><title>Reduction of blood pressure in obese hyperinsulinaemic hypertensive patients during somatostatin infusion</title></json:item><json:item><author><json:item><name>W. Creutzfeldt</name></json:item><json:item><name>R. Arnold</name></json:item></author><host><volume>27</volume><pages><first>1309</first></pages><author></author><title>Metabolism</title></host><title>Somatostatin and the stomach: Exocrine and endocrine aspects</title></json:item><json:item><author><json:item><name>C. B. Lamers</name></json:item></author><host><volume>286</volume><pages><last>25</last><first>19</first></pages><issue>Suppl.</issue><author></author><title>Acta Endocrinology (Copenhagen)</title></host><title>Clinical and pathophysiological aspects of somatostatin and the gastrointestinal tract</title></json:item><json:item><author><json:item><name>R. Luft</name></json:item><json:item><name>S. Efendic</name></json:item><json:item><name>T. Hökfelt</name></json:item></author><host><volume>14</volume><pages><first>1</first></pages><author></author><title>Diabetologia</title></host><title>Somatostatin—both hormone and neurotransmitter?</title></json:item><json:item><author><json:item><name>C. McIntosh</name></json:item><json:item><name>R. Arnold</name></json:item></author><host><volume>27</volume><pages><first>1317</first></pages><author></author><title>Metabolism</title></host><title>Gastrointestinal somatostatin in man and dog</title></json:item><json:item><author><json:item><name>A. G. E. Pearse</name></json:item><json:item><name>J. M. Polak</name></json:item><json:item><name>S. R. Bloom</name></json:item></author><host><volume>72</volume><pages><last>761</last><first>746</first></pages><author></author><title>Gastroenterology</title></host><title>The newer gut hormones: Cellular sources, physiology, pathology and clinical aspects</title></json:item><json:item><author><json:item><name>V. Schusdziarra</name></json:item></author><host><volume>29</volume><pages><last>80</last><first>75</first></pages><author></author><title>Hormone Research</title></host><title>Physiological significance of gastrointestinal somatostatin</title></json:item><json:item><author><json:item><name>V. Schusdziarra</name></json:item><json:item><name>E. Zyznar</name></json:item><json:item><name>D. Rouiller</name></json:item></author><host><volume>207</volume><pages><last>532</last><first>530</first></pages><author></author><title>Science</title></host><title>Splanchnic somatostatin: A hormonal regulator of nutrient homeostasis</title></json:item><json:item><author><json:item><name>A. Verrillo</name></json:item><json:item><name>A. De Teresa</name></json:item><json:item><name>C. Martino</name></json:item><json:item><name>G. Die Chiatra</name></json:item><json:item><name>L. Verrillo</name></json:item></author><host><volume>21</volume><pages><last>195</last><first>185</first></pages><author></author><title>Regulatory Peptides</title></host><title>Somatostatin response to glucose before and after prolonged fasting in lean and obese non‐diabetic subjects</title></json:item><json:item><author><json:item><name>O. Wisen</name></json:item><json:item><name>H. Bjorvell</name></json:item><json:item><name>P. Cantor</name></json:item><json:item><name>C. Johansson</name></json:item><json:item><name>E. Theodorsson</name></json:item></author><host><volume>39</volume><pages><last>54</last><first>43</first></pages><author></author><title>Regulatory Peptides</title></host><title>Plasma concentrations of regulatory peptides in obesity following modified sham feeding (MSF) and a liquid test meal</title></json:item></refBibs><genre><json:string>brief-communication</json:string></genre><host><volume>15</volume><publisherId><json:string>EAT</json:string></publisherId><pages><total>4</total><last>102</last><first>99</first></pages><issn><json:string>0276-3478</json:string></issn><issue>1</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1098-108X</json:string></eissn><title>International Journal of Eating Disorders</title><doi><json:string>10.1002/(ISSN)1098-108X</json:string></doi></host><categories><wos><json:string>social science</json:string><json:string>psychology, clinical</json:string><json:string>psychiatry</json:string><json:string>science</json:string><json:string>psychology</json:string><json:string>nutrition & dietetics</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>psychology & cognitive sciences</json:string><json:string>clinical psychology</json:string></scienceMetrix></categories><publicationDate>1994</publicationDate><copyrightDate>1994</copyrightDate><doi><json:string>10.1002/1098-108X(199401)15:1>99::AID-EAT2260150112>3.0.CO;2-X</json:string></doi><id>3C153FBF4D802C29BCF9A3FC5CDF9172BA316206</id><score>0.90301883</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/3C153FBF4D802C29BCF9A3FC5CDF9172BA316206/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/3C153FBF4D802C29BCF9A3FC5CDF9172BA316206/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3C153FBF4D802C29BCF9A3FC5CDF9172BA316206/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Somatostatin in eating disorders</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><availability><p>Copyright © 1994 Wiley Periodicals, Inc., A Wiley Company</p></availability><date>1994</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Somatostatin in eating disorders</title><author xml:id="author-1"><persName><forename type="first">Karl M.</forename><surname>Pirke</surname></persName><roleName type="degree">M.D.</roleName><note type="biography">Professor of Medicine</note><affiliation>Professor of Medicine</affiliation><affiliation>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</affiliation><affiliation>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</affiliation></author><author xml:id="author-2"><persName><forename type="first">Elisabeth</forename><surname>Frieß</surname></persName><roleName type="degree">M.D.</roleName><note type="biography">Research Assistant</note><affiliation>Research Assistant</affiliation><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation></author><author xml:id="author-3"><persName><forename type="first">Michael B.</forename><surname>Kellner</surname></persName><roleName type="degree">M.D.</roleName><note type="biography">Research Assistant</note><affiliation>Research Assistant</affiliation><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation></author><author xml:id="author-4"><persName><forename type="first">Jürgen‐C.</forename><surname>Krieg</surname></persName><roleName type="degree">M.D.</roleName><note type="biography">Professor of Psychiatry</note><affiliation>Professor of Psychiatry</affiliation><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation></author><author xml:id="author-5"><persName><forename type="first">Manfred M.</forename><surname>Fichter</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Professor of Psychiatry and Director of the Hospital of Behavioral Medicine, Roseneck 6, 8210 Prien, Germany</affiliation></author></analytic><monogr><title level="j">International Journal of Eating Disorders</title><title level="j" type="abbrev">Int. 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Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. 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Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="10"><doi origin="wiley" registered="yes">10.1002/1098-108X(199401)15:1<>1.0.CO;2-M</doi><numberingGroup><numbering type="journalVolume" number="15">15</numbering><numbering type="journalIssue">1</numbering></numberingGroup><coverDate startDate="1994-01">January 1994</coverDate></publicationMeta><publicationMeta level="unit" type="shortCommunication" position="12" status="forIssue"><doi origin="wiley" registered="yes">10.1002/1098-108X(199401)15:1<99::AID-EAT2260150112>3.0.CO;2-X</doi><idGroup><id type="unit" value="EAT2260150112"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="publisher">Copyright © 1994 Wiley Periodicals, Inc., A Wiley Company</copyright><eventGroup><event type="manuscriptAccepted" date="1993-04-30"></event><event type="firstOnline" date="2006-02-13"></event><event type="publishedOnlineFinalForm" date="2006-02-13"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-06"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-18"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-23"></event></eventGroup><numberingGroup><numbering type="pageFirst">99</numbering><numbering type="pageLast">102</numbering></numberingGroup><correspondenceTo>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:EAT.EAT2260150112.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="12"></count></countGroup><titleGroup><title type="main" xml:lang="en">Somatostatin in eating disorders</title><title type="short" xml:lang="en">Somatostatin</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Karl M.</givenNames><familyName>Pirke</familyName><degrees>M.D.</degrees></personName><jobTitle>Professor of Medicine</jobTitle></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Elisabeth</givenNames><familyName>Frieß</familyName><degrees>M.D.</degrees></personName><jobTitle>Research Assistant</jobTitle></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Michael B.</givenNames><familyName>Kellner</familyName><degrees>M.D.</degrees></personName><jobTitle>Research Assistant</jobTitle></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Jürgen‐C.</givenNames><familyName>Krieg</familyName><degrees>M.D.</degrees></personName><jobTitle>Professor of Psychiatry</jobTitle></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Manfred M.</givenNames><familyName>Fichter</familyName><degrees>M.D.</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="DE" type="organization"><unparsedAffiliation>Professor of Psychiatry and Director of the Hospital of Behavioral Medicine, Roseneck 6, 8210 Prien, Germany</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Somatostatin concentrations in plasma were measured before and after a standardized fat and protein‐rich fluid test meal in patients with anorexia nervosa, weight‐recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Somatostatin in eating disorders</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Somatostatin</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Somatostatin in eating disorders</title></titleInfo><name type="personal"><namePart type="given">Karl M.</namePart><namePart type="family">Pirke</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</affiliation><affiliation>Center of Psychbiology and Psychosomatic Research, Department of Psychoendocrinology, University of Trier, Building D, Box 3825, 54286 Trier, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role><description>Professor of Medicine</description></name><name type="personal"><namePart type="given">Elisabeth</namePart><namePart type="family">Frieß</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role><description>Research Assistant</description></name><name type="personal"><namePart type="given">Michael B.</namePart><namePart type="family">Kellner</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role><description>Research Assistant</description></name><name type="personal"><namePart type="given">Jürgen‐C.</namePart><namePart type="family">Krieg</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Max‐Planck‐lnstitut of Psychiatry, Kraepelinstr. 10, 8000 Munich 40, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role><description>Professor of Psychiatry</description></name><name type="personal"><namePart type="given">Manfred M.</namePart><namePart type="family">Fichter</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Professor of Psychiatry and Director of the Hospital of Behavioral Medicine, Roseneck 6, 8210 Prien, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="brief-communication" displayLabel="shortCommunication"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">1994-01</dateIssued><dateValid encoding="w3cdtf">1993-04-30</dateValid><copyrightDate encoding="w3cdtf">1994</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">12</extent></physicalDescription><abstract lang="en">Somatostatin concentrations in plasma were measured before and after a standardized fat and protein‐rich fluid test meal in patients with anorexia nervosa, weight‐recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p < .01) in the anorectic patients as compared with healthy controls and weight‐recovered anorectics. Obese women had blunted somatostatin responses. The findings may explain alterations in insulin secretion and in gastric emptying described earlier in patients with eating disorders. © 1994 by John Wiley & Sons, Inc.</abstract><relatedItem type="host"><titleInfo><title>International Journal of Eating Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Int. J. Eat. Disord.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0276-3478</identifier><identifier type="eISSN">1098-108X</identifier><identifier type="DOI">10.1002/(ISSN)1098-108X</identifier><identifier type="PublisherID">EAT</identifier><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>99</start><end>102</end><total>4</total></extent></part></relatedItem><identifier type="istex">3C153FBF4D802C29BCF9A3FC5CDF9172BA316206</identifier><identifier type="DOI">10.1002/1098-108X(199401)15:1<99::AID-EAT2260150112>3.0.CO;2-X</identifier><identifier type="ArticleID">EAT2260150112</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 1994 Wiley Periodicals, Inc., A Wiley Company</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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