| Ident. | Authors (with country if any) | Title |
|---|
| 000028 (2020) |
Qian Wang [République populaire de Chine] ; Nannan Zhu [République populaire de Chine] ; Jiayuan Hu [République populaire de Chine] ; Yan Wang [République populaire de Chine] ; Jun Xu [République populaire de Chine] ; Qiong Gu [République populaire de Chine] ; Paul M. Lieberman [États-Unis] ; Yan Yuan [États-Unis] | The mTOR inhibitor manassantin B reveals a crucial role of mTORC2 signaling in Epstein-Barr virus reactivation. |
| 000198 (2019) |
Sophie Reidman [Israël] ; Adiel Cohen [Israël] ; Martin Kupiec [Israël] ; Ronit Weisman [Israël] | The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast. |
| 000199 (2019) |
Christos Andreadis [République populaire de Chine] ; Lydia Hulme [Royaume-Uni] ; Katherine Wensley [Royaume-Uni] ; Ji-Long Liu [République populaire de Chine, Royaume-Uni] | The TOR pathway modulates cytoophidium formation in Schizosaccharomyces pombe. |
| 000277 (2019) |
Rui Sun [États-Unis] ; Erdong Cheng [États-Unis] ; Celestino Velásquez [États-Unis] ; Yuan Chang [États-Unis] ; Patrick S. Moore [États-Unis] | Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E). |
| 000312 (2019) |
Saeedah Musaed Almutairi [Canada, Arabie saoudite] ; Alaa Kassim Ali [Canada] ; William He [Canada] ; Doo-Seok Yang [Canada] ; Peyman Ghorbani [Canada] ; Lisheng Wang [Canada] ; Morgan D. Fullerton [Canada] ; Seung-Hwan Lee [Canada] | Interleukin-18 up-regulates amino acid transporters and facilitates amino acid-induced mTORC1 activation in natural killer cells. |
| 000468 (2018) |
Clélia Bourgoint [Suisse] ; Delphine Rispal [Suisse] ; Marina Berti [Suisse] ; Ireos Filipuzzi [Suisse] ; Stephen B. Helliwell [Suisse] ; Manoël Prouteau [Suisse] ; Robbie Loewith [Suisse] | Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae. |
| 000476 (2018) |
Shekoufeh Almasi ; Barry E. Kennedy ; Mariam El-Aghil ; Andra M. Sterea ; Shashi Gujar [Canada] ; Santiago Partida-Sánchez [États-Unis] ; Yassine El Hiani [Canada] | TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway. |
| 000481 (2018) |
Adiel Cohen ; Aline Habib [Israël] ; Dana Laor [Israël] ; Sudhanshu Yadav ; Martin Kupiec [Israël] ; Ronit Weisman [Israël] | TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. |
| 000548 (2018) |
Kathleen A. Boyle [États-Unis] ; Jonathan Van Wickle ; R Blake Hill [États-Unis] ; Adriano Marchese [États-Unis] ; Balaraman Kalyanaraman [États-Unis] ; Michael B. Dwinell [États-Unis] | Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. |
| 000576 (2018) |
Grant R. Campbell [États-Unis] ; Rachel S. Bruckman [États-Unis] ; Shayna D. Herns [États-Unis] ; Shweta Joshi [États-Unis] ; Donald L. Durden [États-Unis] ; Stephen A. Spector [États-Unis] | Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. |
| 000628 (2018) |
Sneha A. Thomas [Canada] ; Devki Nandan [Canada] ; Jennifer Kass [Canada] ; Neil E. Reiner [Canada] | Countervailing, time-dependent effects on host autophagy promotes intracellular survival of Leishmania. |
| 000651 (2018) |
Nitesh Kumar Khandelwal [Inde] ; Neeraj Chauhan [États-Unis] ; Parijat Sarkar [Inde] ; Brooke D. Esquivel [États-Unis] ; Paola Coccetti [Italie] ; Ashutosh Singh [Inde] ; Alix T. Coste [Suisse] ; Meghna Gupta [Inde, États-Unis] ; Dominique Sanglard [Suisse] ; Theodore C. White [États-Unis] ; Murielle Chauvel [France] ; Christophe D'Enfert [France] ; Amitabha Chattopadhyay [Inde] ; Naseem A. Gaur ; Alok Kumar Mondal [Inde] ; Rajendra Prasad [Oman, Inde] | Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling. |
| 000688 (2017) |
Kristin Dauner ; Walaa Eid [Canada] ; Riya Raghupathy ; John F. Presley [Canada] ; Xiaohui Zha [Canada] | mTOR complex 1 activity is required to maintain the canonical endocytic recycling pathway against lysosomal delivery. |
| 000693 (2017) |
Tomoko Kawamata ; Tetsuro Horie [Japon] ; Miou Matsunami ; Michiko Sasaki ; Yoshinori Ohsumi [Japon] | Zinc starvation induces autophagy in yeast. |
| 000694 (2017) |
Binbin Ding [États-Unis] ; Qing Zhong [États-Unis] | Zinc deficiency: An unexpected trigger for autophagy. |
| 000757 (2017) |
Cecilia Primo ; Alba Ferri-Blázquez ; Robbie Loewith [Suisse] ; Lynne Yenush [Espagne] | Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation. |
| 000768 (2017) |
Cheng-Kang Chiang [Canada, Taïwan] ; Aleksander Tworak ; Brian M. Kevany ; Bo Xu [Canada] ; Janice Mayne [Canada] ; Zhibin Ning [Canada] ; Daniel Figeys [Canada] ; Krzysztof Palczewski [États-Unis] | Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium. |
| 000835 (2017) |
Kimberly M. Alonge ; Gordon P. Meares [États-Unis] ; F Bradley Hillgartner [États-Unis] | Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4. |
| 000838 (2017) |
Wenjie Yuan [République populaire de Chine] ; Shuguang Guo ; Jiaoqi Gao [République populaire de Chine] ; Mingming Zhong ; Gonghong Yan ; Wangmeng Wu ; Yapeng Chao [République populaire de Chine] ; Yu Jiang [États-Unis] | General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin Complex 1 in Response to Amino Acid Starvation in Saccharomyces cerevisiae. |
| 000896 (2017) |
Barbara Kroczynska [États-Unis] ; Gavin T. Blyth ; Robert L. Rafidi ; Beata Majchrzak-Kita [Canada] ; Lucy Xu ; Diana Saleiro ; Ewa M. Kosciuczuk [États-Unis] ; Jacek Jemielity [Pologne] ; Bing Su [République populaire de Chine] ; Jessica K. Altman [États-Unis] ; Elizabeth A. Eklund [États-Unis] ; Eleanor N. Fish [Canada] ; Leonidas C. Platanias [États-Unis] | Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses. |
| 000A05 (2016) |
Reinhard Zech [Allemagne] ; Stephan Kiontke [Allemagne] ; Uwe Mueller ; Andrea Oeckinghaus ; Daniel Kümmel [Allemagne] | Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis. |
| 000A33 (2016) |
Shanshan Pei ; Mohammad Minhajuddin ; Angelo D'Alessandro [États-Unis] ; Travis Nemkov [États-Unis] ; Brett M. Stevens ; Biniam Adane ; Nabilah Khan ; Fred K. Hagen ; Vinod K. Yadav ; Subhajyoti De ; John M. Ashton [États-Unis] ; Kirk C. Hansen [États-Unis] ; Jonathan A. Gutman ; Daniel A. Pollyea ; Peter A. Crooks [États-Unis] ; Clayton Smith ; Craig T. Jordan [États-Unis] | Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells. |
| 000A72 (2016) |
Handong Zheng ; Xing Zhang ; Eliseo F. Castillo ; Yan Luo [République populaire de Chine] ; Meilian Liu [États-Unis] ; Xuexian O. Yang [États-Unis] | Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease. |
| 000B00 (2016) |
Adiel Cohen ; Martin Kupiec [Israël] ; Ronit Weisman [Israël] | Gad8 Protein Is Found in the Nucleus Where It Interacts with the MluI Cell Cycle Box-binding Factor (MBF) Transcriptional Complex to Regulate the Response to DNA Replication Stress. |
| 000B74 (2015) |
William C. Merrick [États-Unis] | eIF4F: a retrospective. |
| 000B85 (2015) |
Ge Niu ; Huan Zhang ; Dan Liu ; Li Chen ; Chandra Belani [États-Unis] ; Hong-Gang Wang [États-Unis] ; Hua Cheng [États-Unis] | Tid1, the Mammalian Homologue of Drosophila Tumor Suppressor Tid56, Mediates Macroautophagy by Interacting with Beclin1-containing Autophagy Protein Complex. |
| 000B96 (2015) |
Diego Rojas-Benitez ; Patrick C. Thiaville ; Valérie De Crécy-Lagard ; Alvaro Glavic [Chili] | The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth. |
| 000C05 (2015) |
Delphine Rispal [Suisse] ; Sandra Eltschinger [Suisse] ; Michael Stahl [Suisse] ; Stefania Vaga [Suisse] ; Bernd Bodenmiller [Suisse] ; Yann Abraham ; Ireos Filipuzzi ; N Rao Movva ; Ruedi Aebersold [Suisse] ; Stephen B. Helliwell [Oman] ; Robbie Loewith [Suisse] | Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways. |
| 000C25 (2015) |
Tatsuhiro Sato [Japon] ; Hitomi Akasu ; Wataru Shimono ; Chisa Matsu ; Yuki Fujiwara ; Yoshio Shibagaki ; Jeffrey J. Heard ; Fuyuhiko Tamanoi ; Seisuke Hattori | Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity. |
| 000C76 (2015) |
Bruno D. Fonseca [Oman] ; Chadi Zakaria [Canada] ; Jian-Jun Jia [Canada] ; Tyson E. Graber [Canada] ; Yuri Svitkin [Canada] ; Soroush Tahmasebi [Canada] ; Danielle Healy [Canada] ; Huy-Dung Hoang [Canada] ; Jacob M. Jensen [Danemark] ; Ilo T. Diao [Danemark] ; Alexandre Lussier [Canada] ; Christopher Dajadian [Canada] ; Niranjan Padmanabhan [Canada] ; Walter Wang [Canada] ; Edna Matta-Camacho [Canada] ; Jaclyn Hearnden [Canada] ; Ewan M. Smith [Royaume-Uni] ; Yoshinori Tsukumo [Canada] ; Akiko Yanagiya [Canada] ; Masahiro Morita [Canada] ; Emmanuel Petroulakis [Canada] ; Jose L. González [Mexique] ; Greco Hernández [Mexique] ; Tommy Alain [Canada] ; Christian K. Damgaard [Danemark] | La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1). |
| 000D12 (2015) |
Manuel E. Sanchez-Casalongue ; Jaehoon Lee ; Aviva Diamond ; Scott Shuldiner ; Robyn D. Moir ; Ian M. Willis [États-Unis] | Differential phosphorylation of a regulatory subunit of protein kinase CK2 by target of rapamycin complex 1 signaling and the Cdc-like kinase Kns1. |
| 000D18 (2015) |
Marie-Elodie Cattin [Canada] ; Jessica Wang ; Jonathan J. Weldrick [Canada] ; Cassandra L. Roeske [Canada] ; Esther Mak [Canada] ; Stephanie L. Thorn [Canada] ; Jean N. Dasilva [Canada] ; Yibin Wang ; Aldon J. Lusis ; Patrick G. Burgon [Canada] | Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. |
| 000D44 (2015) |
Ann K. Rosenthal ; Claudia M. Gohr [États-Unis] ; Elizabeth Mitton-Fitzgerald [États-Unis] ; Rupinder Grewal [États-Unis] ; James Ninomiya ; Carolyn B. Coyne [États-Unis] ; William T. Jackson | Autophagy modulates articular cartilage vesicle formation in primary articular chondrocytes. |
| 000D45 (2015) |
Grant R. Campbell [États-Unis] ; Rachel S. Bruckman [États-Unis] ; Yen-Lin Chu [États-Unis] ; Stephen A. Spector [États-Unis] | Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1. |
| 000D46 (2015) |
Masaaki Nakayama ; Tetsuyoshi Inoue ; Mariko Naito [Japon] ; Koji Nakayama [Japon] ; Naoya Ohara [Japon] | Attenuation of the phosphatidylinositol 3-kinase/Akt signaling pathway by Porphyromonas gingivalis gingipains RgpA, RgpB, and Kgp. |
| 000E07 (2014) |
Myriam Crapeau [Belgique] ; Ahmad Merhi [Belgique] ; Bruno André [Belgique] | Stress conditions promote yeast Gap1 permease ubiquitylation and down-regulation via the arrestin-like Bul and Aly proteins. |
| 000E19 (2014) |
Stephanie K. Evans [Royaume-Uni] ; Karl E V. Burgess [Royaume-Uni] ; Joseph V. Gray [Royaume-Uni] | Recovery from rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (TORC1) supports residual proliferation that dilutes rapamycin among progeny cells. |
| 000E41 (2014) |
Daniele Stracka ; Szymon Jozefczuk [Suisse] ; Florian Rudroff [Suisse] ; Uwe Sauer [Suisse] ; Michael N. Hall [Suisse] | Nitrogen source activates TOR (target of rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins. |
| 000E82 (2014) |
Michael J. Lang [États-Unis] ; Jorge Y. Martinez-Marquez [États-Unis] ; Derek C. Prosser ; Laura R. Ganser [États-Unis] ; Destiney Buelto [États-Unis] ; Beverly Wendland ; Mara C. Duncan [États-Unis] | Glucose starvation inhibits autophagy via vacuolar hydrolysis and induces plasma membrane internalization by down-regulating recycling. |
| 000E83 (2014) |
Adiel Cohen ; Martin Kupiec [Israël] ; Ronit Weisman [Israël] | Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway. |
| 000E95 (2014) |
Nour El Houda Benbahouche [France] ; Ioannis Iliopoulos ; István Török ; Joachim Marhold ; Julien Henri ; Andrey V. Kajava ; Robert Farkaš ; Tore Kempf ; Martina Schnölzer ; Philippe Meyer ; István Kiss ; Edouard Bertrand ; Bernard M. Mechler ; Bérengère Pradet-Balade | Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries. |
| 000F05 (2014) |
Rajendra Rai [États-Unis] ; Jennifer J. Tate ; Isabelle Georis ; Evelyne Dubois ; Terrance G. Cooper | Constitutive and nitrogen catabolite repression-sensitive production of Gat1 isoforms. |
| 000F09 (2014) |
Kimberly Coffman [États-Unis] ; Bing Yang ; Jie Lu ; Ashley L. Tetlow ; Emelia Pelliccio ; Shan Lu ; Da-Chuan Guo ; Chun Tang ; Meng-Qiu Dong ; Fuyuhiko Tamanoi | Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis. |
| 000F35 (2014) |
Rajendra Rai [États-Unis] ; Jennifer J. Tate [États-Unis] ; Karthik Shanmuganatham [États-Unis] ; Martha M. Howe [États-Unis] ; Terrance G. Cooper [États-Unis] | A domain in the transcription activator Gln3 specifically required for rapamycin responsiveness. |
| 000F45 (2013) |
Rajendra Rai [États-Unis] ; Jennifer J. Tate ; David R. Nelson ; Terrance G. Cooper | gln3 mutations dissociate responses to nitrogen limitation (nitrogen catabolite repression) and rapamycin inhibition of TorC1. |
| 000F54 (2013) |
Tammy Pracheil [États-Unis] ; Zhengchang Liu | Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum. |
| 000F68 (2013) |
Miriam Schonbrun [Israël] ; Masha Kolesnikov ; Martin Kupiec ; Ronit Weisman | TORC2 is required to maintain genome stability during S phase in fission yeast. |
| 000F75 (2013) |
Yoan R. Monneau [France] ; Heddy Soufari ; Christopher J. Nelson ; Cameron D. Mackereth | Structure and activity of the peptidyl-prolyl isomerase domain from the histone chaperone Fpr4 toward histone H3 proline isomerization. |
| 001008 (2013) |
Charulatha Gururaj [États-Unis] ; Ross S. Federman ; Ross Federman ; Amy Chang | Orm proteins integrate multiple signals to maintain sphingolipid homeostasis. |
| 001050 (2013) |
Jennifer J. Tate [États-Unis] ; Terrance G. Cooper | Five conditions commonly used to down-regulate tor complex 1 generate different physiological situations exhibiting distinct requirements and outcomes. |
| 001076 (2013) |
Andre Feller [Belgique] ; Isabelle Georis ; Jennifer J. Tate ; Terrance G. Cooper ; Evelyne Dubois | Alterations in the Ure2 αCap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitation. |
