| Ident. | Authors (with country if any) | Title |
|---|
| 000337 (2019) |
Tanveer Sharif [Canada] ; Emma Martell [Canada] ; Cathleen Dai [Canada] ; Mohammad Saleh Ghassemi-Rad [Canada] ; Mark Robert Hanes [Canada] ; Patrick J. Murphy [Canada] ; Nandini N. Margam [Canada] ; Hirendrasinh B. Parmar [Canada] ; Carman A. Giacomantonio [Canada] ; Roy Duncan [Canada] ; Patrick W K. Lee [Canada] ; Shashi Gujar [Canada] | HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells. |
| 000338 (2019) |
Christopher Mogg [Canada] ; Christopher Bonner [Canada] ; Li Wang [Canada] ; Johann Schernthaner [Canada] ; Myron Smith [Canada] ; Darrell Desveaux [Canada] ; Rajagopal Subramaniam [Canada] | Genomic Identification of the TOR Signaling Pathway as a Target of the Plant Alkaloid Antofine in the Phytopathogen Fusarium graminearum. |
| 000354 (2019) |
Jean-Pierre Routy [Canada] ; Stéphane Isnard [Canada] ; Vikram Mehraj [Canada] ; Mario Ostrowski [Canada] ; Nicolas Chomont [Canada] ; Petronela Ancuta [Canada] ; Rosalie Ponte [Canada] ; Delphine Planas [Canada] ; Franck P. Dupuy [Canada] ; Jonathan B. Angel [Canada] | Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol. |
| 000360 (2019) |
Kara M. Ruicci [Canada] ; Paul Plantinga [Canada] ; Nicole Pinto [Canada] ; Mohammed I. Khan [Canada] ; William Stecho [Canada] ; Sandeep S. Dhaliwal [Canada] ; John Yoo [Canada] ; Kevin Fung [Canada] ; Danielle Macneil [Canada] ; Joe S. Mymryk [Canada] ; John W. Barrett [Canada] ; Christopher J. Howlett [Canada] ; Anthony C. Nichols [Canada] | Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition. |
| 000373 (2019) |
Patricia Lakin-Thomas [Canada] | Circadian rhythms, metabolic oscillators, and the target of rapamycin (TOR) pathway: the Neurospora connection. |
| 000396 (2019) |
Truc T. Losier [Canada] ; Mercy Akuma [Canada] ; Olivia C. Mckee-Muir [Canada] ; Nicholas D. Leblond [Canada] ; Yujin Suk [Canada] ; Reham M. Alsaadi [Canada] ; Zhihao Guo [Canada] ; Ryan Reshke [Canada] ; Subash Sad [Canada] ; François-Xavier Campbell-Valois [Canada] ; Derrick J. Gibbings [Canada] ; Morgan D. Fullerton [Canada] ; Ryan C. Russell [Canada] | AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. |
| 000410 (2019) |
Angela C. Zhou [Canada] ; Nathália V. Batista [Canada] ; Tania H. Watts [Canada] | 4-1BB Regulates Effector CD8 T Cell Accumulation in the Lung Tissue through a TRAF1-, mTOR-, and Antigen-Dependent Mechanism to Enhance Tissue-Resident Memory T Cell Formation during Respiratory Influenza Infection. |
| 000411 (2019) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Erhan Keles [Suisse] ; Jacob A. Mcphail [Canada] ; Reece M. Hoffmann [Canada] ; Anna Melone [Suisse] ; Chiara Borsari [Suisse] ; Rohitha Sriramaratnam [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Paul Hebeisen [Suisse] ; Doriano Fabbro [Suisse] ; Petra Hillmann [Suisse] ; John E. Burke [Canada] ; Matthias P. Wymann [Suisse] | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. |
| 000433 (2018) |
Laura Hulea [Canada] ; Simon-Pierre Gravel [Canada] ; Masahiro Morita [Japon] ; Marie Cargnello [France] ; Oro Uchenunu [Canada] ; Young Kyuen Im [Canada] ; Camille Lehuédé [Canada] ; Eric H. Ma [Canada] ; Matthew Leibovitch [Canada] ; Shannon Mclaughlan [Canada] ; Marie-José Blouin [Canada] ; Maxime Parisotto [Canada] ; Vasilios Papavasiliou [Canada] ; Cynthia Lavoie [Canada] ; Ola Larsson [Suède] ; Michael Ohh [Canada] ; Tiago Ferreira [Canada] ; Celia Greenwood [Canada] ; Gaëlle Bridon [Canada] ; Daina Avizonis [Canada] ; Gerardo Ferbeyre [Canada] ; Peter Siegel [Canada] ; Russell G. Jones [Canada] ; William Muller [Canada] ; Josie Ursini-Siegel [Canada] ; Julie St-Pierre [Canada] ; Michael Pollak [Canada] ; Ivan Topisirovic [Canada] | Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. |
| 000441 (2018) |
Fatemeh Khadir [Iran, Canada] ; Christopher R. Shaler [Canada] ; Ahmad Oryan [Iran] ; Patrick T. Rudak [Canada] ; Delfina M. Mazzuca [Canada] ; Tahereh Taheri [Iran] ; Jimmy D. Dikeakos [Canada] ; S M Mansour Haeryfar [Canada] ; Sima Rafati [Iran] | Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin. |
| 000446 (2018) |
David S. Hui [Hong Kong] ; Nelson Lee [Canada] ; Paul K. Chan [Hong Kong] ; John H. Beigel [États-Unis] | The role of adjuvant immunomodulatory agents for treatment of severe influenza. |
| 000461 (2018) |
Louis-Philippe Leroux [Canada] ; Julie Lorent [Suède] ; Tyson E. Graber [Canada] ; Visnu Chaparro [Canada] ; Laia Masvidal [Suède] ; Maria Aguirre [Canada] ; Bruno D. Fonseca [Canada] ; Léon C. Van Kempen [Canada, Pays-Bas] ; Tommy Alain [Canada] ; Ola Larsson [Suède] ; Maritza Jaramillo [Canada] | The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome. |
| 000476 (2018) |
Shekoufeh Almasi ; Barry E. Kennedy ; Mariam El-Aghil ; Andra M. Sterea ; Shashi Gujar [Canada] ; Santiago Partida-Sánchez [États-Unis] ; Yassine El Hiani [Canada] | TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway. |
| 000506 (2018) |
Elizabeth I. Vink [États-Unis] ; Sora Lee [États-Unis] ; James R. Smiley [Canada] ; Ian Mohr [États-Unis] | Remodeling mTORC1 Responsiveness to Amino Acids by the Herpes Simplex Virus UL46 and Us3 Gene Products Supports Replication during Nutrient Insufficiency. |
| 000512 (2018) |
Julie Barsalou [Canada] ; Annaliesse Blincoe [Canada] ; Isabel Fernandez [Canada] ; Dorothée Dal-Soglio [Canada] ; Lorie Marchitto [Canada] ; Silvia Selleri [Canada] ; Elie Haddad [Canada] ; Aissa Benyoucef [Canada] ; Fabien Touzot [Canada] | Rapamycin as an Adjunctive Therapy for NLRC4 Associated Macrophage Activation Syndrome. |
| 000539 (2018) |
Gabriel Castro-Falc N [États-Unis] ; Grant S. Seiler [États-Unis] ; Özlem Demir [États-Unis] ; Manoj K. Rathinaswamy [Canada] ; David Hamelin [Canada] ; Reece M. Hoffmann [Canada] ; Stefanie L. Makowski [États-Unis] ; Anne-Catrin Letzel [États-Unis] ; Seth J. Field [États-Unis] ; John E. Burke [Canada] ; Rommie E. Amaro [États-Unis] ; Chambers C. Hughes [États-Unis] | Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester. |
| 000611 (2018) |
Chao Wang [Canada] ; Maria I. Edilova [Canada] ; Lisa E. Wagar [Canada] ; Shariq Mujib [Canada] ; Meromit Singer [États-Unis] ; Nicole F. Bernard [Canada] ; Thérèse Croughs [France] ; Michael M. Lederman [États-Unis] ; Irini Sereti [États-Unis] ; Margaret A. Fischl [États-Unis] ; Elisabeth Kremmer [Allemagne] ; Mario Ostrowski [Canada] ; Jean-Pierre Routy [Canada] ; Tania H. Watts [Canada] | Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy. |
| 000613 (2018) |
Kara M. Ruicci [Canada] ; Nicole Pinto [Canada] ; Mohammed I. Khan [Canada] ; John Yoo [Canada] ; Kevin Fung [Canada] ; Danielle Macneil [Canada] ; Joe S. Mymryk [Canada] ; John W. Barrett [Canada] ; Anthony C. Nichols [Canada] | ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition. |
| 000619 (2018) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Anna Melone [Suisse] ; Jean-Baptiste Langlois [Suisse] ; Chiara Borsari [Suisse] ; Petra Hillmann [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Marketa Zvelebil [Suisse] ; Paul Hebeisen [Suisse] ; Wolfgang Löscher [Allemagne] ; John Burke [Canada] ; Doriano Fabbro [Suisse] ; Matthias P. Wymann [Suisse] | Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders. |
| 000628 (2018) |
Sneha A. Thomas [Canada] ; Devki Nandan [Canada] ; Jennifer Kass [Canada] ; Neil E. Reiner [Canada] | Countervailing, time-dependent effects on host autophagy promotes intracellular survival of Leishmania. |
| 000629 (2018) |
Iva Lu I [Autriche] ; Manoj K. Rathinaswamy [Canada] ; Linda Truebestein [Autriche] ; David J. Hamelin [Canada] ; John E. Burke [Canada] ; Thomas A. Leonard [Autriche] | Conformational sampling of membranes by Akt controls its activation and inactivation. |
