1232 | Humans |
995 | Sirolimus |
939 | Animals |
934 | Signal Transduction |
818 | Saccharomyces cerevisiae |
768 | TOR Serine-Threonine Kinases |
686 | Saccharomyces cerevisiae Proteins |
496 | Mice |
420 | Autophagy |
372 | Female |
354 | Male |
343 | Phosphorylation |
343 | Mechanistic Target of Rapamycin Complex 1 |
317 | Immunosuppressive Agents |
308 | Gene Expression Regulation, Fungal |
292 | Transcription Factors |
279 | Protein-Serine-Threonine Kinases |
279 | Phosphatidylinositol 3-Kinases |
254 | Multiprotein Complexes |
235 | Mutation |
199 | Cell Line, Tumor |
197 | Cell Line |
194 | Cell Proliferation |
187 | Protein Kinases |
181 | Fungal Proteins |
177 | Middle Aged |
177 | Mice, Inbred C57BL |
176 | Cells, Cultured |
173 | Proto-Oncogene Proteins c-akt |
169 | Antifungal Agents |
169 | Adult |
160 | Molecular Sequence Data |
160 | Amino Acid Sequence |
148 | Carrier Proteins |
146 | Protein Binding |
139 | Nitrogen |
137 | Models, Biological |
137 | Apoptosis |
134 | Transcription, Genetic |
134 | Cell Cycle Proteins |
133 | Virus Replication |
126 | Kidney Transplantation |
126 | Adaptor Proteins, Signal Transducing |
121 | Mechanistic Target of Rapamycin Complex 2 |
117 | DNA-Binding Proteins |
109 | Tacrolimus |
108 | Gene Expression Regulation |
108 | Cell Survival |
105 | Phosphotransferases (Alcohol Group Acceptor) |
101 | Time Factors |
100 | Schizosaccharomyces |
100 | RNA, Messenger |
100 | Intracellular Signaling Peptides and Proteins |
97 | Protein Biosynthesis |
95 | Disease Models, Animal |
93 | Mitochondria |
91 | Gene Deletion |
90 | Macrophages |
90 | Aged |
89 | Mice, Knockout |
87 | Blotting, Western |
87 | Antineoplastic Agents |
87 | Amino Acids |
86 | Genes, Fungal |
85 | Protein Kinase Inhibitors |
85 | Host-Pathogen Interactions |
83 | Repressor Proteins |
83 | Protein Transport |
82 | Membrane Proteins |
81 | Enzyme Activation |
80 | Cell Differentiation |
77 | Schizosaccharomyces pombe Proteins |
75 | Stress, Physiological |
74 | Gene Expression Profiling |
73 | Phosphoproteins |
73 | Mice, Inbred BALB C |
73 | Base Sequence |
71 | Vacuoles |
71 | Cell Nucleus |
70 | Everolimus |
70 | Cytokines |
69 | Phenotype |
68 | Graft Rejection |
68 | Glucose |
67 | Gene Expression |
67 | Cell Cycle |
65 | T-Lymphocytes |
65 | Down-Regulation |
64 | Tacrolimus Binding Proteins |
64 | Polyenes |
64 | Lymphocyte Activation |
64 | Cell Membrane |
63 | Oxidative Stress |
62 | Recombinant Fusion Proteins |
62 | Reactive Oxygen Species |
61 | Phagosomes |
60 | Promoter Regions, Genetic |
60 | Cyclosporine |
59 | Yeasts |
59 | Treatment Outcome |
58 | Antibiotics, Antineoplastic |
57 | RNA, Small Interfering |
57 | Microtubule-Associated Proteins |
57 | Lysosomes |
56 | Protein Phosphatase 2 |
55 | Flow Cytometry |
54 | Ribosomal Protein S6 Kinases, 70-kDa |
54 | Phosphoinositide-3 Kinase Inhibitors |
52 | Risk Factors |
52 | HeLa Cells |
52 | Cyclic AMP-Dependent Protein Kinases |
52 | AMP-Activated Protein Kinases |
51 | Up-Regulation |
51 | Rats |
51 | Graft Survival |
51 | Cell Division |
51 | Candida albicans |
51 | Antiviral Agents |
50 | Immunity, Innate |
49 | HEK293 Cells |
48 | Fibroblasts |
48 | Drug Resistance, Fungal |
48 | Anti-Bacterial Agents |
47 | Sequence Homology, Amino Acid |
47 | Retrospective Studies |
47 | Neoplasms |
47 | Monomeric GTP-Binding Proteins |
47 | Enzyme Inhibitors |
46 | Ribosomes |
46 | Phosphoprotein Phosphatases |
46 | Immunosuppression |
46 | Cytomegalovirus Infections |
45 | RNA Interference |
45 | Proteins |
44 | Viral Load |
44 | Protein Processing, Post-Translational |
44 | Microscopy, Fluorescence |
44 | Inflammation |
44 | Heat-Shock Proteins |
44 | Drug Therapy, Combination |
44 | Cytoplasm |
43 | Mice, Transgenic |
43 | Longevity |
43 | Gene Expression Regulation, Neoplastic |
42 | T-Lymphocytes, Regulatory |
42 | Protein Structure, Tertiary |
42 | Postoperative Complications |
42 | Dose-Response Relationship, Drug |
42 | Autophagy-Related Proteins |
41 | Epithelial Cells |
41 | CD8-Positive T-Lymphocytes |
40 | Xenograft Model Antitumor Assays |
40 | Trans-Activators |
40 | Polyomavirus Infections |
40 | Peptidylprolyl Isomerase |
40 | MAP Kinase Signaling System |
40 | Green Fluorescent Proteins |
40 | B-Lymphocytes |
39 | Homeostasis |
39 | Herpesvirus 4, Human |
39 | HIV-1 |
39 | HIV Infections |
39 | CD4-Positive T-Lymphocytes |
38 | Liver Transplantation |
38 | Forkhead Transcription Factors |
38 | Cytomegalovirus |
38 | Culture Media |
37 | Young Adult |
37 | Virulence |
37 | Ribosomal Proteins |
37 | Plasmids |
37 | Mycophenolic Acid |
37 | DNA Damage |
37 | Aging |
37 | Adolescent |
36 | Transfection |
36 | Proteomics |
36 | Drug Resistance, Neoplasm |
36 | Cloning, Molecular |
36 | BK Virus |
35 | Oligonucleotide Array Sequence Analysis |
35 | Nuclear Proteins |
35 | Models, Molecular |
35 | Mitogen-Activated Protein Kinases |
35 | Liver Neoplasms |
35 | Binding Sites |
34 | Sequence Alignment |
34 | Recombinant Proteins |
34 | Epstein-Barr Virus Infections |
34 | Energy Metabolism |
33 | Sarcoma, Kaposi |
33 | Polymerase Chain Reaction |
33 | Hepacivirus |
33 | Biomarkers |
32 | Tumor Suppressor Proteins |
32 | Immunocompromised Host |
32 | Bacterial Proteins |
31 | Transcriptome |
31 | Reverse Transcriptase Polymerase Chain Reaction |
31 | NF-kappa B |
31 | Carcinoma, Hepatocellular |
31 | Amino Acid Transport Systems |
30 | Tacrolimus Binding Protein 1A |
30 | Microbial Viability |
30 | Mice, Nude |
30 | Immunoblotting |
30 | Herpesvirus 8, Human |
30 | Hepatitis C |
30 | Glutamine |
30 | Genome, Fungal |
30 | Endoplasmic Reticulum |
30 | Dendritic Cells |
30 | Cell Movement |
30 | Biological Transport |
30 | Beclin-1 |
30 | Active Transport, Cell Nucleus |
29 | Tumor Virus Infections |
29 | Swine |
29 | PTEN Phosphohydrolase |
29 | Lung |
29 | Interferon-gamma |
29 | Glycogen Synthase Kinase 3 |
29 | GATA Transcription Factors |
29 | Calcineurin |
29 | Breast Neoplasms |
28 | Viral Proteins |
28 | Transcriptional Activation |
28 | Cell Wall |
28 | Calcineurin Inhibitors |
28 | Apoptosis Regulatory Proteins |
27 | Vesicular Transport Proteins |
27 | Tumor Cells, Cultured |
27 | Transplantation, Homologous |
27 | RNA, Viral |
27 | Organ Transplantation |
27 | Morpholines |
27 | Microbial Sensitivity Tests |
27 | Immunologic Memory |
27 | Hepatocytes |
27 | Glycolysis |
27 | Genotype |
27 | Gene Regulatory Networks |
27 | Gene Knockdown Techniques |
27 | DNA, Viral |
27 | Autophagosomes |
27 | Actins |
26 | Temperature |
26 | Sphingolipids |
26 | Real-Time Polymerase Chain Reaction |
26 | RNA-Binding Proteins |
26 | RNA, Fungal |
26 | Mycobacterium tuberculosis |
26 | Liver |
26 | Immunohistochemistry |
26 | Hyphae |
26 | Gene Knockout Techniques |
26 | Follow-Up Studies |
26 | Drug Synergism |
26 | Drosophila Proteins |
26 | Disease Progression |
26 | DNA, Fungal |
26 | DNA Primers |
26 | Conserved Sequence |
26 | Child |
26 | Adenine |
25 | Streptomyces |
25 | Prospective Studies |
25 | MicroRNAs |
25 | Immunoprecipitation |
25 | Enzyme-Linked Immunosorbent Assay |
25 | Endosomes |
25 | Caloric Restriction |
24 | ras Proteins |
24 | Virus Activation |
24 | Lipid Metabolism |
24 | Eukaryotic Initiation Factor-4E |
24 | Endocytosis |
24 | Drosophila melanogaster |
23 | Spores, Fungal |
23 | Proto-Oncogene Proteins |
23 | Papillomavirus Infections |
23 | Neurons |
23 | Molecular Targeted Therapy |
23 | Kinetics |
23 | Interleukin-2 |
23 | Insulin |
23 | Drug Resistance, Microbial |
23 | Chromatin |
23 | Cellular Senescence |
23 | Cell Death |
23 | Antineoplastic Combined Chemotherapy Protocols |
22 | Prognosis |
22 | Monocytes |
22 | Mitosis |
22 | Membrane Transport Proteins |
22 | Kidney |
22 | Intracellular Membranes |
22 | Hepatitis B virus |
22 | DNA Replication |
22 | Carbon |
22 | Alleles |
21 | Structure-Activity Relationship |
21 | Ribosomal Protein S6 Kinases |
21 | Rapamycin-Insensitive Companion of mTOR Protein |
21 | Proteome |
21 | Protein Subunits |
21 | Peptides |
21 | Mass Spectrometry |
21 | Lymphoproliferative Disorders |
21 | Lipopolysaccharides |
21 | Histones |
21 | Golgi Apparatus |
21 | Genetic Vectors |
21 | Gene Silencing |
21 | G1 Phase |
21 | Escherichia coli |
21 | Chromones |
21 | Cell Cycle Checkpoints |
21 | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors |
21 | Antibodies, Monoclonal |
21 | Aged, 80 and over |
20 | Tuberous Sclerosis Complex 2 Protein |
20 | Sequence Analysis, DNA |
20 | STAT3 Transcription Factor |
20 | Regulatory-Associated Protein of mTOR |
20 | Mutagenesis |
20 | Mitochondrial Proteins |
20 | Mammals |
20 | Lung Neoplasms |
20 | Liver Cirrhosis |
20 | Kidney Diseases |
20 | Immune Tolerance |
20 | Computational Biology |
20 | Autophagy-Related Protein 5 |
19 | Two-Hybrid System Techniques |
19 | Tumor Necrosis Factor-alpha |
19 | Substrate Specificity |
19 | Reproducibility of Results |
19 | RNA, Transfer |
19 | Protein Conformation |
19 | Phosphatidylinositol 3-Kinase |
19 | Peptide Fragments |
19 | Models, Genetic |
19 | Mice, SCID |
19 | Metformin |
19 | Intestines |
19 | Interleukin-10 |
19 | Incidence |
19 | Chlorocebus aethiops |
19 | Caffeine |
18 | Wortmannin |
18 | Ubiquitination |
18 | Species Specificity |
18 | Rats, Sprague-Dawley |
18 | Prions |
18 | Osmotic Pressure |
18 | Oncogene Protein v-akt |
18 | Neoplasm Proteins |
18 | Molecular Structure |
18 | Microscopy, Electron, Transmission |
18 | Metabolic Networks and Pathways |
18 | Membrane Potential, Mitochondrial |
18 | Kidney Failure, Chronic |
18 | Histone Deacetylases |
18 | Hepatitis B |
18 | Hep G2 Cells |
18 | Genes, Reporter |
18 | Gastrointestinal Microbiome |
18 | Fermentation |
18 | Brain |
18 | Blotting, Northern |
18 | Arabidopsis |
18 | Androstadienes |
17 | Viremia |
17 | Vascular Endothelial Growth Factor A |
17 | Spleen |
17 | Serine |
17 | Saccharomycetales |
17 | RNA, Ribosomal |
17 | Phagocytosis |
17 | Papillomaviridae |
17 | Opportunistic Infections |
17 | Oncolytic Virotherapy |
17 | Mutagenesis, Site-Directed |
17 | Ligands |
17 | Leukocytes, Mononuclear |
17 | Killer Cells, Natural |
17 | Infant |
17 | Hypoxia-Inducible Factor 1, alpha Subunit |
17 | Glutathione Peroxidase |
17 | Gene Expression Regulation, Viral |
17 | Fungi |
17 | Fatty Acids |
17 | Eukaryotic Initiation Factors |
17 | Drug Interactions |
17 | DNA, Ribosomal |
17 | Cyclic AMP |
17 | Child, Preschool |
17 | Calcium |
17 | Caenorhabditis elegans |
16 | Tumor Suppressor Protein p53 |
16 | Tuberculosis |
16 | T-Lymphocyte Subsets |
16 | Survival Analysis |
16 | Sequestosome-1 Protein |
16 | Sequence Deletion |
16 | Proteolysis |
16 | Protein Kinase C |
16 | Phylogeny |
16 | Oxidation-Reduction |
16 | Leucine |
16 | Intestinal Mucosa |
16 | Heart Transplantation |
16 | Extracellular Signal-Regulated MAP Kinases |
16 | Epigenesis, Genetic |
16 | Cyclins |
16 | Autophagy-Related Protein-1 Homolog |
16 | Aspergillus fumigatus |
16 | 14-3-3 Proteins |
15 | Virus Latency |
15 | Virus Diseases |
15 | Triazoles |
15 | Tissue Donors |
15 | Th17 Cells |
15 | Survival Rate |
15 | Ras Homolog Enriched in Brain Protein |
15 | Rabbits |
15 | RNA Polymerase III |
15 | Pyrimidines |
15 | Pyridines |
15 | Proto-Oncogene Proteins c-bcl-2 |
15 | Protein Domains |
15 | Molecular Chaperones |
15 | MCF-7 Cells |
15 | Jurkat Cells |
15 | Interleukin-6 |
15 | Evolution, Molecular |
15 | Endosomal Sorting Complexes Required for Transport |
15 | Endoplasmic Reticulum Stress |
15 | Adenosine Triphosphate |
14 | Vero Cells |
14 | Tuberous Sclerosis Complex 1 Protein |
14 | Transplant Recipients |
14 | Transforming Growth Factor beta |
14 | Telomere |
14 | Recurrence |
14 | Receptors, Antigen, T-Cell |
14 | Point Mutation |
14 | Plant Diseases |
14 | Phosphoric Monoester Hydrolases |
14 | Neoplasm Invasiveness |
14 | Naphthyridines |
14 | Mice, Inbred NOD |
14 | Meiosis |
14 | Macaca mulatta |
14 | Immunophilins |
14 | Imidazoles |
14 | Heterografts |
14 | Genomic Instability |
14 | Gene Library |
14 | Fluorescent Antibody Technique |
14 | Fish Diseases |
14 | Doxorubicin |
14 | Diet |
14 | Cycloheximide |
14 | Cricetinae |
14 | Cattle |
14 | Carcinoma, Squamous Cell |
14 | Carcinogenesis |
14 | Amino Acid Substitution |
14 | Amino Acid Isomerases |
13 | Transplantation, Heterologous |
13 | RAW 264.7 Cells |
13 | Proto-Oncogene Proteins c-myc |
13 | Protein-Tyrosine Kinases |
13 | Protein Multimerization |
13 | Oxygen |
13 | Organisms, Genetically Modified |
13 | Open Reading Frames |
13 | Neoplastic Stem Cells |
13 | Mycoses |
13 | Lung Transplantation |
13 | Kidney Neoplasms |
13 | Hydrogen Peroxide |
13 | Herpesvirus 1, Human |
13 | Glutamic Acid |
13 | DNA Repair |
13 | Cytosol |
13 | Cohort Studies |
13 | Cell Transformation, Viral |
13 | Candidiasis |
13 | Biomarkers, Tumor |
13 | Arabidopsis Proteins |
13 | Antilymphocyte Serum |
12 | Viral Nonstructural Proteins |
12 | Ubiquitin-Protein Ligases |
12 | Th1 Cells |
12 | Staphylococcus aureus |
12 | Receptors, Cytoplasmic and Nuclear |
12 | Random Allocation |