| Ident. | Authors (with country if any) | Title |
|---|
| 000105 (2019) |
Ya Yu Chernoryzh [Russie] ; N E Fedorova [Russie] ; K I Yurlov [Russie] ; R A Simonov [Russie] ; A B Kornev [Russie] ; D S Karpov [Russie] ; N F Zakirova [Russie] ; A V Ivanov [Russie] ; A A Kushch [Russie] ; A L Gintsburg [Russie] | Resistance of THP-1 Leukemia Cells Infected with Cytomegalovirus to Anti-tumor Antibiotic Doxorubicin and Restoration of the Sensitivity by Inhibitors of the PI3K/AKT/mTOR Molecular Pathway. |
| 000114 (2020) |
Manuel Méndez-G Mez [Mexique] ; Elda Castro-Mercado [Mexique] ; César Arturo Pe A-Uribe [Mexique] ; Homero Reyes-De La Cruz [Mexique] ; José L Pez-Bucio [Mexique] ; Ernesto García-Pineda [Mexique] | TARGET OF RAPAMYCIN signaling plays a role in Arabidopsis growth promotion by Azospirillum brasilense Sp245. |
| 000133 (2020) |
Guochao Jia [République populaire de Chine] ; Xiaofeng Liu ; Na Che ; Yongjun Xia ; Guangqiang Wang ; Zhiqiang Xiong ; Hui Zhang ; Lianzhong Ai | Human-origin Lactobacillus salivarius AR809 protects against immunosuppression in S. aureus-induced pharyngitis via Akt-mediated NF-κB and autophagy signaling pathways. |
| 000210 (2019) |
David C. Fajgenbaum ; Ruth-Anne Langan ; Alberto Sada Japp [États-Unis] ; Helen L. Partridge ; Sheila K. Pierson ; Amrit Singh [Canada] ; Daniel J. Arenas ; Jason R. Ruth [États-Unis] ; Christopher S. Nabel [États-Unis] ; Katie Stone [États-Unis] ; Mariko Okumura [États-Unis] ; Anthony Schwarer [Australie] ; Fábio Freire Jose ; Nelson Hamerschlak [Brésil] ; Gerald B. Wertheim [États-Unis] ; Michael B. Jordan [États-Unis] ; Adam D. Cohen [États-Unis] ; Vera Krymskaya ; Arthur Rubenstein ; Michael R. Betts [États-Unis] ; Taku Kambayashi [États-Unis] ; Frits Van Rhee [États-Unis] ; Thomas S. Uldrick [États-Unis] | Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease. |
| 000214 (2019) |
Kara M. Ruicci [Canada] ; Paul Plantinga [Canada] ; Nicole Pinto [Canada] ; Mohammed I. Khan [Canada] ; William Stecho [Canada] ; Sandeep S. Dhaliwal [Canada] ; John Yoo [Canada] ; Kevin Fung [Canada] ; Danielle Macneil [Canada] ; Joe S. Mymryk [Canada] ; John W. Barrett [Canada] ; Christopher J. Howlett [Canada] ; Anthony C. Nichols [Canada] | Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition. |
| 000216 (2019) |
Claudio Scuoppo [États-Unis] ; Jiguang Wang [États-Unis] ; Mirjana Persaud [États-Unis] ; Sandeep K. Mittan [États-Unis] ; Katia Basso [États-Unis] ; Laura Pasqualucci [États-Unis] ; Raul Rabadan [États-Unis] ; Giorgio Inghirami [États-Unis] ; Carla Grandori [États-Unis] ; Francesc Bosch [États-Unis, Espagne] ; Riccardo Dalla-Favera [États-Unis] | Repurposing dasatinib for diffuse large B cell lymphoma. |
| 000226 (2019) |
Jau-Tien Lin [Taïwan] ; Yuan-Yen Chang [Taïwan] ; Yi-Chen Chen [Taïwan] ; Po-Lin Liao [Taïwan] ; Deng-Jye Yang [Taïwan] | Litchi (Litchi chinensis Sonn.) flower proanthocyanidin fraction exhibited protective efficacy to suppress nickel-induced expression for vascular endothelial growth factor in HepG2 cells. |
| 000235 (2019) |
Phillip C. Spinosa [États-Unis] ; Brock A. Humphries [États-Unis] ; Daniela Lewin Mejia [États-Unis] ; Johanna M. Buschhaus [États-Unis] ; Jennifer J. Linderman [États-Unis] ; Gary D. Luker [États-Unis] ; Kathryn E. Luker [États-Unis] | Short-term cellular memory tunes the signaling responses of the chemokine receptor CXCR4. |
| 000241 (2019) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Erhan Keles [Suisse] ; Jacob A. Mcphail [Canada] ; Reece M. Hoffmann [Canada] ; Anna Melone [Suisse] ; Chiara Borsari [Suisse] ; Rohitha Sriramaratnam [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Paul Hebeisen [Suisse] ; Doriano Fabbro [Suisse] ; Petra Hillmann [Suisse] ; John E. Burke [Canada] ; Matthias P. Wymann [Suisse] | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. |
| 000280 (2019) |
Cristiane J. Nunes-Santos [Brésil] ; Gulbu Uzel ; Sergio D. Rosenzweig | PI3K pathway defects leading to immunodeficiency and immune dysregulation. |
| 000314 (2019) |
Yueh-Han Hsu [Taïwan] ; Hui-Pei Huang [Taïwan] ; Horng-Rong Chang [Taïwan] | The uremic toxin p-cresol promotes the invasion and migration on carcinoma cells via Ras and mTOR signaling. |
| 000346 (2019) |
Ruifang Wang [République populaire de Chine] ; Yinxing Zhu [République populaire de Chine] ; Xian Lin [République populaire de Chine] ; Chenwei Ren [République populaire de Chine] ; Jiachang Zhao [République populaire de Chine] ; Fangfang Wang [République populaire de Chine] ; Xiaochen Gao [République populaire de Chine] ; Rong Xiao [République populaire de Chine] ; Lianzhong Zhao [République populaire de Chine] ; Huanchun Chen [République populaire de Chine] ; Meilin Jin [République populaire de Chine] ; Wenjun Ma [États-Unis] ; Hongbo Zhou [République populaire de Chine] | Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production. |
| 000371 (2019) |
Jing Li [France] ; Ignacio Vázquez-García [Royaume-Uni, États-Unis] ; Karl Persson [Suède] ; Asier González [Suisse] ; Jia-Xing Yue [France] ; Benjamin Barré [France] ; Michael N. Hall [Suisse] ; Anthony Long [États-Unis] ; Jonas Warringer [Suède] ; Ville Mustonen [Finlande] ; Gianni Liti [France] | Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales. |
| 000416 (2018) |
Gabriel Castro-Falc N [États-Unis] ; Grant S. Seiler [États-Unis] ; Özlem Demir [États-Unis] ; Manoj K. Rathinaswamy [Canada] ; David Hamelin [Canada] ; Reece M. Hoffmann [Canada] ; Stefanie L. Makowski [États-Unis] ; Anne-Catrin Letzel [États-Unis] ; Seth J. Field [États-Unis] ; John E. Burke [Canada] ; Rommie E. Amaro [États-Unis] ; Chambers C. Hughes [États-Unis] | Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester. |
| 000420 (2018) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Anna Melone [Suisse] ; Jean-Baptiste Langlois [Suisse] ; Chiara Borsari [Suisse] ; Petra Hillmann [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Marketa Zvelebil [Suisse] ; Paul Hebeisen [Suisse] ; Wolfgang Löscher [Allemagne] ; John Burke [Canada] ; Doriano Fabbro [Suisse] ; Matthias P. Wymann [Suisse] | Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders. |
| 000443 (2018) |
Elizabeth I. Vink [États-Unis] ; Sora Lee [États-Unis] ; James R. Smiley [Canada] ; Ian Mohr [États-Unis] | Remodeling mTORC1 Responsiveness to Amino Acids by the Herpes Simplex Virus UL46 and Us3 Gene Products Supports Replication during Nutrient Insufficiency. |
| 000444 (2018) |
Samana Batool [République populaire de Chine] ; Thomson Patrick Joseph [République populaire de Chine] ; Mushraf Hussain [République populaire de Chine] ; Miza S. Vuai [République populaire de Chine] ; Kavish H. Khinsar [République populaire de Chine] ; Syed Riaz Ud Din [République populaire de Chine] ; Arshad Ahmed Padhiar [République populaire de Chine] ; Mintao Zhong [République populaire de Chine] ; Anhong Ning [République populaire de Chine] ; Wei Zhang [République populaire de Chine] ; Jing Cao [République populaire de Chine] ; Min Huang [République populaire de Chine] | LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901. |
| 000539 (2018) |
Charlene Ranadheera [Canada] ; Kevin M. Coombs [Canada] ; Darwyn Kobasa [Canada] | Comprehending a Killer: The Akt/mTOR Signaling Pathways Are Temporally High-Jacked by the Highly Pathogenic 1918 Influenza Virus. |
| 000541 (2018) |
Andrew Hill [États-Unis] ; Brad Niles [États-Unis] ; Andrew Cuyegkeng [États-Unis] ; Ted Powers [États-Unis] | Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly. |
| 000552 (2018) |
Isabel Rodríguez-Escudero [Espagne] ; Teresa Fernández-Acero [Espagne] ; Víctor J. Cid [Espagne] ; María Molina [Espagne] | Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae. |
| 000570 (2018) |
Akihiro Kondo [Japon] ; Md Golam Mostofa [Japon] ; Katsuya Miyake [Japon] ; Mashu Terasawa [Japon] ; Islam Nafisa [Japon] ; Akter M S T. Yeasmin [Japon] ; Talukdar Muhammad Waliullah [Japon] ; Tomotake Kanki [Japon] ; Takashi Ushimaru [Japon] | Cdc14 Phosphatase Promotes TORC1-Regulated Autophagy in Yeast. |
