11q13 is a susceptibility locus for hormone receptor positive breast cancer
Identifieur interne : 002611 ( Istex/Curation ); précédent : 002610; suivant : 00261211q13 is a susceptibility locus for hormone receptor positive breast cancer
Auteurs : Diether Lambrechts [Belgique] ; Therese Truong [France] ; Christina Justenhoven [Allemagne] ; Manjeet K. Humphreys [Royaume-Uni] ; Jean Wang [Royaume-Uni] ; John L. Hopper [Australie] ; Gillian S. Dite [Australie] ; Carmel Apicella [Australie] ; Melissa C. Southey [Australie] ; Marjanka K. Schmidt [Pays-Bas] ; Annegien Broeks [Pays-Bas] ; Sten Cornelissen [Pays-Bas] ; Richard Van Hien [Pays-Bas] ; Elinor Sawyer [Royaume-Uni] ; Ian Tomlinson [Royaume-Uni] ; Michael Kerin [Irlande (pays)] ; Nicola Miller [Irlande (pays)] ; Roger L. Milne [Espagne] ; M. Pilar Zamora [Espagne] ; José Ignacio Arias Pérez [Espagne] ; Javier Benítez [Espagne] ; Ute Hamann [Allemagne] ; Yon-Dschun Ko [Allemagne] ; Thomas Brüning [Allemagne] ; Jenny Chang-Claude [Allemagne] ; Ursel Eilber [Allemagne] ; Rebecca Hein [Allemagne] ; Stefan Nickels [Allemagne] ; Dieter Flesch-Janys [Allemagne] ; Shan Wang-Gohrke [Allemagne] ; Esther M. John [États-Unis] ; Alexander Miron [États-Unis] ; Robert Winqvist [Finlande] ; Katri Pylk S [Finlande] ; Arja Jukkola-Vuorinen [Finlande] ; Mervi Grip [Finlande] ; Georgia Chenevix-Trench [Australie] ; Jonathan Beesley [Australie] ; Xiaoqing Chen [Australie] ; Kconfab Investigators [Australie] ; Florence Menegaux [France] ; Emilie Cordina-Duverger [France] ; Chen-Yang Shen [Taïwan] ; Jyh-Cherng Yu [Taïwan] ; Pei-Ei Wu [Taïwan] ; Ming-Feng Hou [Taïwan] ; Irene L. Andrulis [Canada] ; Teresa Selander [Canada] ; Gord Glendon [Canada] ; Anna Marie Mulligan [Canada] ; Hoda Anton-Culver [États-Unis] ; Argyrios Ziogas [États-Unis] ; Kenneth R. Muir [Royaume-Uni] ; Artitaya Lophatananon [Royaume-Uni] ; Suthee Rattanamongkongul [Thaïlande] ; Puttisak Puttawibul [Thaïlande] ; Michael Jones [Royaume-Uni] ; Nicholas Orr [Royaume-Uni] ; Alan Ashworth [Royaume-Uni] ; Anthony Swerdlow [Royaume-Uni] ; Gianluca Severi [Australie] ; Laura Baglietto [Australie] ; Graham Giles [Australie] ; Melissa Southey [Australie] ; Federik Marmé [Allemagne] ; Andreas Schneeweiss [Allemagne] ; Christof Sohn [Allemagne] ; Barbara Burwinkel [Allemagne] ; Betul T. Yesilyurt [Belgique] ; Patrick Neven [Belgique] ; Robert Paridaens [Belgique] ; Hans Wildiers [Belgique] ; Hermann Brenner [Allemagne] ; Heiko Müller [Allemagne] ; Volker Arndt [Allemagne] ; Christa Stegmaier [Allemagne] ; Alfons Meindl [Allemagne] ; Sarah Schott [Allemagne] ; Claus R. Bartram [Allemagne] ; Rita K. Schmutzler [Allemagne] ; Angela Cox [Royaume-Uni] ; Ian W. Brock [Royaume-Uni] ; Graeme Elliott [Royaume-Uni] ; Simon S. Cross [Royaume-Uni] ; Peter A. Fasching [États-Unis] ; Ruediger Schulz-Wendtland [Allemagne] ; Arif B. Ekici [Allemagne] ; Matthias W. Beckmann [Allemagne] ; Olivia Fletcher [Royaume-Uni] ; Nichola Johnson [Royaume-Uni] ; Isabel Dos Santos Silva [Royaume-Uni] ; Julian Peto [Royaume-Uni] ; Heli Nevanlinna [Finlande] ; Taru A. Muranen [Finlande] ; Kristiina Aittom Ki [Finlande] ; Carl Blomqvist [Finlande] ; Thilo Dörk [Allemagne] ; Peter Schürmann [Allemagne] ; Michael Bremer [Allemagne] ; Peter Hillemanns [Allemagne] ; Natalia V. Bogdanova [Allemagne] ; Natalia N. Antonenkova [Biélorussie] ; Yuri I. Rogov [Biélorussie] ; Johann H. Karstens [Allemagne] ; Elza Khusnutdinova [Russie] ; Marina Bermisheva [Russie] ; Darya Prokofieva [Russie] ; Shamil Gancev [Russie] ; Anna Jakubowska [Pologne] ; Jan Lubinski [Pologne] ; Katarzyna Jaworska [Pologne] ; Katarzyna Durda [Pologne] ; B Rge G. Nordestgaard [Danemark] ; Stig E. Bojesen [Danemark] ; Charlotte Lanng [Danemark] ; Arto Mannermaa [Finlande] ; Vesa Kataja [Finlande] ; Veli-Matti Kosma [Finlande] ; Jaana M. Hartikainen [Finlande] ; Paolo Radice [Italie] ; Paolo Peterlongo [Italie] ; Siranoush Manoukian [Italie] ; Loris Bernard [Italie] ; Fergus J. Couch [États-Unis] ; Janet E. Olson [États-Unis] ; Xianshu Wang [États-Unis] ; Zachary Fredericksen [États-Unis] ; Grethe Grenaker Aln S [Norvège] ; Vessela Kristensen [Norvège] ; Anne-Lise B Rresen-Dale [Norvège] ; Peter Devilee [Pays-Bas] ; Robert A. E. M. Tollenaar [Pays-Bas] ; Caroline M. Seynaeve [Pays-Bas] ; Maartje J. Hooning [Pays-Bas] ; Montserrat García-Closas [Royaume-Uni] ; Stephen J. Chanock [États-Unis] ; Jolanta Lissowska [Pologne] ; Mark E. Sherman [États-Unis] ; Per Hall [Suède] ; Jianjun Liu [Suède] ; Kamila Czene [Suède] ; Daehee Kang [Corée du Sud] ; Keun-Young Yoo [Corée du Sud] ; Dong-Young Noh [Corée du Sud] ; Annika Lindblom [Suède] ; Sara Margolin [Suède] ; Alison M. Dunning [Royaume-Uni] ; Paul D. P. Pharoah [Royaume-Uni] ; Douglas F. Easton [Royaume-Uni] ; Pascal Guénel [France] ; Hiltrud Brauch [Allemagne]Source :
- Human Mutation [ 1059-7794 ] ; 2012-07.
Descripteurs français
- Wicri :
- geographic : Finlande.
- topic : Cancer, Consortium, épidémiologie, Génétique, Histologie, Recherche médicale, Médecine du travail, Oulu.
English descriptors
- KwdEn :
- Abcfs, Academia sinica, Accident insurance, Acute lymphoblastic leukaemia, Allele, Asian descent, Asian women, Association study, Bcac, Biocenter kuopio, Biomedical research centre, Biomedical sciences, Brca1, Brca1 mutations, Breakthrough breast cancer, Breakthrough breast cancer research centre, Breast, Breast cancer, Breast cancer association consortium, Breast cancer cases, Breast cancer family registry, Breast cancer patients, Breast cancer risk, Breast cancer susceptibility loci, Bsuch study, Cancer, Cancer care ontario, Cancer council victoria, Cancer epidemiology, Cancer foundation, Cancer genetics, Cancer institute, Cancer prevention institute, Cancer research, Cancer research centre, Cancer studies, Cecile study, Cell cycle control, Centre, Clin, Clin cancer, Clinical genetics, Clinical medicine, Clinical pharmacology, College london, Common variants, Consortium, Coriell institute, Coronary artery disease, Cyclin, Deutsche krebshilfe, Deutsches krebsforschungszentrum, Dkfz, Ductal, Dutch cancer society, Eastern finland, Epidemiol, Epidemiology, Erlangen, Estrogen, Estrogen breast cancer, Estrogen receptor, European descent, European women, Evangelische kliniken bonn ggmbh, Familial breast cancer risk, Family history, Federal ministry, Finland, Fondazione irccs istituto nazionale tumori, Forest plots, Foundation trust, Gene expression, General population, Genet, Genetic variants, Genetics, German cancer research center, Gwas, Heidelberg, Helmholtz society, Helsinki, Helsinki university, Herlev university hospital, Heterogeneity, Heterozygous, Hiltrud brauch, Histology, Histology ductal, Histopathological subtype, Homozygous effect, Horizontal lines, Hormone receptor status, Human cancer genetics programme, Human genetics, Human mutation, Inst, Internal medicine, Johanniter krankenhaus, Kuopio, Kuopio university hospital, Laboratory medicine, Leiden university, Lobular, Locus, Mammographic density, Many others, Mayo clinic, Medical research, Medical research council, Melbourne, Minor allele frequencies, Molecular epidemiology group, Molecular genetics, Molecular medicine, Mutation, National cancer institute, National health, Natl, Natl cancer inst, Nhmrc, Obstetrics, Occupational medicine, Odds ratio, Odds ratios, Ofbcr, Oncogenic driver, Oncology, Ontario, Ontario cancer genetics network, Other tumors, Oulu, Oulu university hospital, Ovarian cancer, Pancreatic cancer, Polymorphism, Postgraduate school, Receptor, Repair genes, Research centre, Sample sizes, Samuel lunenfeld research institute, Sigrid juselius foundation, Sinai hospital, Single nucleotide polymorphism, Snp, Study abcfs, Study participants, Subgroup analyses, Susceptibility, Tumor characteristics, Tumor subtype, Tumor subtypes, Turnbull, Ucibcs, University breast center, University hospital, University hospital erlangen, University tubingen, Unselected breast cancer patients, Variant, Victorian breast cancer research consortium group leader, Western australia, Wiley periodicals.
- Teeft :
- Abcfs, Academia sinica, Accident insurance, Acute lymphoblastic leukaemia, Allele, Asian descent, Asian women, Association study, Bcac, Biocenter kuopio, Biomedical research centre, Biomedical sciences, Brca1, Brca1 mutations, Breakthrough breast cancer, Breakthrough breast cancer research centre, Breast, Breast cancer, Breast cancer association consortium, Breast cancer cases, Breast cancer family registry, Breast cancer patients, Breast cancer risk, Breast cancer susceptibility loci, Bsuch study, Cancer, Cancer care ontario, Cancer council victoria, Cancer epidemiology, Cancer foundation, Cancer genetics, Cancer institute, Cancer prevention institute, Cancer research, Cancer research centre, Cancer studies, Cecile study, Cell cycle control, Centre, Clin, Clin cancer, Clinical genetics, Clinical medicine, Clinical pharmacology, College london, Common variants, Consortium, Coriell institute, Coronary artery disease, Cyclin, Deutsche krebshilfe, Deutsches krebsforschungszentrum, Dkfz, Ductal, Dutch cancer society, Eastern finland, Epidemiol, Epidemiology, Erlangen, Estrogen, Estrogen breast cancer, Estrogen receptor, European descent, European women, Evangelische kliniken bonn ggmbh, Familial breast cancer risk, Family history, Federal ministry, Finland, Fondazione irccs istituto nazionale tumori, Forest plots, Foundation trust, Gene expression, General population, Genet, Genetic variants, Genetics, German cancer research center, Gwas, Heidelberg, Helmholtz society, Helsinki, Helsinki university, Herlev university hospital, Heterogeneity, Heterozygous, Hiltrud brauch, Histology, Histology ductal, Histopathological subtype, Homozygous effect, Horizontal lines, Hormone receptor status, Human cancer genetics programme, Human genetics, Human mutation, Inst, Internal medicine, Johanniter krankenhaus, Kuopio, Kuopio university hospital, Laboratory medicine, Leiden university, Lobular, Locus, Mammographic density, Many others, Mayo clinic, Medical research, Medical research council, Melbourne, Minor allele frequencies, Molecular epidemiology group, Molecular genetics, Molecular medicine, Mutation, National cancer institute, National health, Natl, Natl cancer inst, Nhmrc, Obstetrics, Occupational medicine, Odds ratio, Odds ratios, Ofbcr, Oncogenic driver, Oncology, Ontario, Ontario cancer genetics network, Other tumors, Oulu, Oulu university hospital, Ovarian cancer, Pancreatic cancer, Polymorphism, Postgraduate school, Receptor, Repair genes, Research centre, Sample sizes, Samuel lunenfeld research institute, Sigrid juselius foundation, Sinai hospital, Single nucleotide polymorphism, Snp, Study abcfs, Study participants, Subgroup analyses, Susceptibility, Tumor characteristics, Tumor subtype, Tumor subtypes, Turnbull, Ucibcs, University breast center, University hospital, University hospital erlangen, University tubingen, Unselected breast cancer patients, Variant, Victorian breast cancer research consortium group leader, Western australia, Wiley periodicals.
Abstract
A recent two‐stage genome‐wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, and rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (P ≤ 3 × 10−9) and weak evidence was observed for rs2380205 (P = 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per‐allele odds ratio 1.21, P = 4 × 10−39). The association for rs614367 was specific to estrogen receptor (ER)‐positive disease and strongest for ER plus progesterone receptor (PR)‐positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype. Hum Mutat 33:1123–1132, 2012. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/humu.22089
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Southey</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. 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University Hospital Galway, Galway, Ireland</mods:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation wicri:level="1"><mods:affiliation>Clinical Science Institute. University Hospital Galway, Galway, Ireland</mods:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. 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Pilar Zamora</name><affiliation wicri:level="1"><mods:affiliation>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="José Ignacio Arias" last="Pérez">José Ignacio Arias Pérez</name><affiliation wicri:level="1"><mods:affiliation>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation wicri:level="1"><mods:affiliation>Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><mods:affiliation>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Ko, Yon Schun" sort="Ko, Yon Schun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><mods:affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum</wicri:regionArea></affiliation></author><author><name sortKey="Chang Laude, Jenny" sort="Chang Laude, Jenny" uniqKey="Chang Laude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Flesch Anys, Dieter" sort="Flesch Anys, Dieter" uniqKey="Flesch Anys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation wicri:level="1"><mods:affiliation>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg‐Eppendorf, Hamburg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg‐Eppendorf, Hamburg</wicri:regionArea></affiliation></author><author><name sortKey="Wang Ohrke, Shan" sort="Wang Ohrke, Shan" uniqKey="Wang Ohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Ulm, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name><affiliation wicri:level="2"><mods:affiliation>Cancer Prevention Institute of California, Fremont, California and Stanford University School of Medicine and Stanford Cancer Institute, Stanford, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cancer Prevention Institute of California, Fremont, California and Stanford University School of Medicine and Stanford Cancer Institute, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name><affiliation wicri:level="2"><mods:affiliation>Dana‐Farber Cancer Institute, Boston, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dana‐Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><mods:affiliation>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><mods:affiliation>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Jukkola Uorinen, Arja" sort="Jukkola Uorinen, Arja" uniqKey="Jukkola Uorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Surgery, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Investigators, Kconfab" sort="Investigators, Kconfab" uniqKey="Investigators K" first="Kconfab" last="Investigators">Kconfab Investigators</name><affiliation wicri:level="1"><mods:affiliation>Peter MacCallum Cancer Center, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Peter MacCallum Cancer Center, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Cordina Uverger, Emilie" sort="Cordina Uverger, Emilie" uniqKey="Cordina Uverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Shen, Chen Ang" sort="Shen, Chen Ang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Jyh Herng" sort="Yu, Jyh Herng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Tri‐Service General Hospital, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Surgery, Tri‐Service General Hospital, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Wu, Pei I" sort="Wu, Pei I" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Hou, Ming Eng" sort="Hou, Ming Eng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name><affiliation wicri:level="1"><mods:affiliation>Cancer Center and Department of Surgery, Kaohsiung Medical University Chung‐Ho Memorial Hospital, Kaohsiung, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Cancer Center and Department of Surgery, Kaohsiung Medical University Chung‐Ho Memorial Hospital, Kaohsiung</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><mods:affiliation>Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name><affiliation wicri:level="1"><mods:affiliation>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><mods:affiliation>Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="1"><mods:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Anton Ulver, Hoda" sort="Anton Ulver, Hoda" uniqKey="Anton Ulver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation wicri:level="2"><mods:affiliation>Department of Epidemiology, University of California Irvine, Irvine, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation wicri:level="2"><mods:affiliation>Department of Epidemiology, University of California Irvine, Irvine, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name><affiliation wicri:level="1"><mods:affiliation>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation wicri:level="1"><mods:affiliation>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea></affiliation></author><author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name><affiliation wicri:level="1"><mods:affiliation>Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok, Thailand</mods:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok</wicri:regionArea></affiliation></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Medical School, Prince Songkla University, Songkla, Thailand</mods:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Surgery, Medical School, Prince Songkla University, Songkla</wicri:regionArea></affiliation></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name><affiliation wicri:level="1"><mods:affiliation>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea></affiliation></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="1"><mods:affiliation>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation wicri:level="1"><mods:affiliation>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name><affiliation wicri:level="1"><mods:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation wicri:level="1"><mods:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name><affiliation wicri:level="1"><mods:affiliation>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation wicri:level="1"><mods:affiliation>Saarland Cancer Registry, Saarbrücken, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Saarland Cancer Registry, Saarbrücken</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><mods:affiliation>Division of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technical University of Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><affiliation wicri:level="1"><mods:affiliation>Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><mods:affiliation>Division of Molecular Gyneco‐Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Gyneco‐Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation wicri:level="1"><mods:affiliation>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="2"><mods:affiliation>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Schulz Endtland, Ruediger" sort="Schulz Endtland, Ruediger" uniqKey="Schulz Endtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><affiliation wicri:level="1"><mods:affiliation>Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation wicri:level="1"><mods:affiliation>Institute of Human Genetics, Friedrich Alexander University Erlangen‐Nuremberg, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Friedrich Alexander University Erlangen‐Nuremberg, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><mods:affiliation>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation wicri:level="1"><mods:affiliation>London School of Hygiene and Tropical Medicine, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="1"><mods:affiliation>London School of Hygiene and Tropical Medicine, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name><affiliation wicri:level="1"><mods:affiliation>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</mods:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea></affiliation></author><author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name><affiliation wicri:level="1"><mods:affiliation>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</mods:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea></affiliation></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name><affiliation wicri:level="1"><mods:affiliation>Bashkirian Medical University, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Bashkirian Medical University, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name><affiliation wicri:level="1"><mods:affiliation>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland; Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland; Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kosma, Veli Atti" sort="Kosma, Veli Atti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><mods:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><mods:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="1"><mods:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation wicri:level="1"><mods:affiliation>Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><mods:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation wicri:level="2"><mods:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation wicri:level="2"><mods:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation wicri:level="2"><mods:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine (Faculty Division Ahus), University of Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea></affiliation></author><author><name sortKey="B Rresen Ale, Anne Ise" sort="B Rresen Ale, Anne Ise" uniqKey="B Rresen Ale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine (Faculty Division Ahus), University of Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><mods:affiliation>Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Losas, Montserrat" sort="Garcia Losas, Montserrat" uniqKey="Garcia Losas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London</wicri:regionArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><mods:affiliation>Department of Cancer Epidemiology and Prevention, M. Sklodowska‐Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Cancer Epidemiology and Prevention, M. Sklodowska‐Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation wicri:level="2"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Yoo, Keun Oung" sort="Yoo, Keun Oung" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Noh, Dong Oung" sort="Noh, Dong Oung" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="1"><mods:affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology Pathology, Karolinska Institutet, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology Pathology, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="1"><mods:affiliation>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>E-mail: hiltrud.brauch@ikp‐stuttgart.de</mods:affiliation><country wicri:rule="url">Allemagne</country></affiliation><affiliation wicri:level="1"><mods:affiliation>Correspondence address: Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, Germany.</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Correspondence address: Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CC63964BFBCF9F28F183C830DFC0B4DD9582A49D</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/humu.22089</idno><idno type="url">https://api.istex.fr/document/CC63964BFBCF9F28F183C830DFC0B4DD9582A49D/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002611</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002611</idno><idno type="wicri:Area/Istex/Curation">002611</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">11q13 is a susceptibility locus for hormone receptor positive breast cancer<ref type="note" target="#fn1"></ref></title><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><mods:affiliation>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation wicri:level="1"><mods:affiliation>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen</wicri:regionArea></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Jean" sort="Wang, Jean" uniqKey="Wang J" first="Jean" last="Wang">Jean Wang</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation wicri:level="1"><mods:affiliation>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name><affiliation wicri:level="1"><mods:affiliation>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation wicri:level="1"><mods:affiliation>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="1"><mods:affiliation>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation wicri:level="1"><mods:affiliation>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Cornelissen, Sten" sort="Cornelissen, Sten" uniqKey="Cornelissen S" first="Sten" last="Cornelissen">Sten Cornelissen</name><affiliation wicri:level="1"><mods:affiliation>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Hien, Richard" sort="Van Hien, Richard" uniqKey="Van Hien R" first="Richard" last="Van Hien">Richard Van Hien</name><affiliation wicri:level="1"><mods:affiliation>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's and St. Thomas' NHS Foundation Trust in partnership with King's College London, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's and St. Thomas' NHS Foundation Trust in partnership with King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="1"><mods:affiliation>Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Kerin, Michael" sort="Kerin, Michael" uniqKey="Kerin M" first="Michael" last="Kerin">Michael Kerin</name><affiliation wicri:level="1"><mods:affiliation>Clinical Science Institute. University Hospital Galway, Galway, Ireland</mods:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation wicri:level="1"><mods:affiliation>Clinical Science Institute. University Hospital Galway, Galway, Ireland</mods:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation wicri:level="1"><mods:affiliation>Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M. Pilar" last="Zamora">M. Pilar Zamora</name><affiliation wicri:level="1"><mods:affiliation>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="José Ignacio Arias" last="Pérez">José Ignacio Arias Pérez</name><affiliation wicri:level="1"><mods:affiliation>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation wicri:level="1"><mods:affiliation>Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><mods:affiliation>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Ko, Yon Schun" sort="Ko, Yon Schun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><mods:affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum</wicri:regionArea></affiliation></author><author><name sortKey="Chang Laude, Jenny" sort="Chang Laude, Jenny" uniqKey="Chang Laude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Flesch Anys, Dieter" sort="Flesch Anys, Dieter" uniqKey="Flesch Anys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation wicri:level="1"><mods:affiliation>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg‐Eppendorf, Hamburg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg‐Eppendorf, Hamburg</wicri:regionArea></affiliation></author><author><name sortKey="Wang Ohrke, Shan" sort="Wang Ohrke, Shan" uniqKey="Wang Ohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Ulm, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name><affiliation wicri:level="2"><mods:affiliation>Cancer Prevention Institute of California, Fremont, California and Stanford University School of Medicine and Stanford Cancer Institute, Stanford, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cancer Prevention Institute of California, Fremont, California and Stanford University School of Medicine and Stanford Cancer Institute, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name><affiliation wicri:level="2"><mods:affiliation>Dana‐Farber Cancer Institute, Boston, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dana‐Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><mods:affiliation>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><mods:affiliation>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Jukkola Uorinen, Arja" sort="Jukkola Uorinen, Arja" uniqKey="Jukkola Uorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Surgery, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation wicri:level="1"><mods:affiliation>Queensland Institute of Medical Research, Brisbane, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Investigators, Kconfab" sort="Investigators, Kconfab" uniqKey="Investigators K" first="Kconfab" last="Investigators">Kconfab Investigators</name><affiliation wicri:level="1"><mods:affiliation>Peter MacCallum Cancer Center, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Peter MacCallum Cancer Center, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Cordina Uverger, Emilie" sort="Cordina Uverger, Emilie" uniqKey="Cordina Uverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Shen, Chen Ang" sort="Shen, Chen Ang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Jyh Herng" sort="Yu, Jyh Herng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Tri‐Service General Hospital, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Surgery, Tri‐Service General Hospital, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Wu, Pei I" sort="Wu, Pei I" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Hou, Ming Eng" sort="Hou, Ming Eng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name><affiliation wicri:level="1"><mods:affiliation>Cancer Center and Department of Surgery, Kaohsiung Medical University Chung‐Ho Memorial Hospital, Kaohsiung, Taiwan</mods:affiliation><country xml:lang="fr">Taïwan</country><wicri:regionArea>Cancer Center and Department of Surgery, Kaohsiung Medical University Chung‐Ho Memorial Hospital, Kaohsiung</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><mods:affiliation>Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name><affiliation wicri:level="1"><mods:affiliation>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><mods:affiliation>Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="1"><mods:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Anton Ulver, Hoda" sort="Anton Ulver, Hoda" uniqKey="Anton Ulver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation wicri:level="2"><mods:affiliation>Department of Epidemiology, University of California Irvine, Irvine, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation wicri:level="2"><mods:affiliation>Department of Epidemiology, University of California Irvine, Irvine, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name><affiliation wicri:level="1"><mods:affiliation>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation wicri:level="1"><mods:affiliation>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea></affiliation></author><author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name><affiliation wicri:level="1"><mods:affiliation>Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok, Thailand</mods:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok</wicri:regionArea></affiliation></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Medical School, Prince Songkla University, Songkla, Thailand</mods:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Surgery, Medical School, Prince Songkla University, Songkla</wicri:regionArea></affiliation></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name><affiliation wicri:level="1"><mods:affiliation>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea></affiliation></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="1"><mods:affiliation>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation wicri:level="1"><mods:affiliation>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="1"><mods:affiliation>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name><affiliation wicri:level="1"><mods:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation wicri:level="1"><mods:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name><affiliation wicri:level="1"><mods:affiliation>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><affiliation wicri:level="1"><mods:affiliation>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="1"><mods:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation wicri:level="1"><mods:affiliation>Saarland Cancer Registry, Saarbrücken, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Saarland Cancer Registry, Saarbrücken</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><mods:affiliation>Division of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technical University of Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><affiliation wicri:level="1"><mods:affiliation>Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><mods:affiliation>Division of Molecular Gyneco‐Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Gyneco‐Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name><affiliation wicri:level="1"><mods:affiliation>Institute for Cancer Studies, Department of Oncology, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation wicri:level="1"><mods:affiliation>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="2"><mods:affiliation>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Schulz Endtland, Ruediger" sort="Schulz Endtland, Ruediger" uniqKey="Schulz Endtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><affiliation wicri:level="1"><mods:affiliation>Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation wicri:level="1"><mods:affiliation>Institute of Human Genetics, Friedrich Alexander University Erlangen‐Nuremberg, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Friedrich Alexander University Erlangen‐Nuremberg, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><mods:affiliation>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation wicri:level="1"><mods:affiliation>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation wicri:level="1"><mods:affiliation>London School of Hygiene and Tropical Medicine, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="1"><mods:affiliation>London School of Hygiene and Tropical Medicine, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name><affiliation wicri:level="1"><mods:affiliation>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</mods:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea></affiliation></author><author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name><affiliation wicri:level="1"><mods:affiliation>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</mods:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea></affiliation></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><affiliation wicri:level="1"><mods:affiliation>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name><affiliation wicri:level="1"><mods:affiliation>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name><affiliation wicri:level="1"><mods:affiliation>Bashkirian Medical University, Ufa, Russia</mods:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Bashkirian Medical University, Ufa</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name><affiliation wicri:level="1"><mods:affiliation>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland; Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland; Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kosma, Veli Atti" sort="Kosma, Veli Atti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</mods:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><mods:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><mods:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="1"><mods:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation wicri:level="1"><mods:affiliation>Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><mods:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation wicri:level="2"><mods:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation wicri:level="2"><mods:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation wicri:level="2"><mods:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine (Faculty Division Ahus), University of Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea></affiliation></author><author><name sortKey="B Rresen Ale, Anne Ise" sort="B Rresen Ale, Anne Ise" uniqKey="B Rresen Ale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Faculty of Medicine (Faculty Division Ahus), University of Oslo, Norway</mods:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><mods:affiliation>Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name><affiliation wicri:level="1"><mods:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</mods:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Losas, Montserrat" sort="Garcia Losas, Montserrat" uniqKey="Garcia Losas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="1"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London</wicri:regionArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><mods:affiliation>Department of Cancer Epidemiology and Prevention, M. Sklodowska‐Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</mods:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Cancer Epidemiology and Prevention, M. Sklodowska‐Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation wicri:level="2"><mods:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Yoo, Keun Oung" sort="Yoo, Keun Oung" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Noh, Dong Oung" sort="Noh, Dong Oung" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name><affiliation wicri:level="1"><mods:affiliation>Seoul National University College of Medicine, Seoul, Republic of Korea</mods:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="1"><mods:affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><mods:affiliation>Department of Oncology Pathology, Karolinska Institutet, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology Pathology, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><mods:affiliation>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>University Paris‐Sud, UMRS 1018, Villejuif, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="1"><mods:affiliation>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>E-mail: hiltrud.brauch@ikp‐stuttgart.de</mods:affiliation><country wicri:rule="url">Allemagne</country></affiliation><affiliation wicri:level="1"><mods:affiliation>Correspondence address: Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, Germany.</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Correspondence address: Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Human Mutation</title><title level="j" type="alt">HUMAN MUTATION</title><idno type="ISSN">1059-7794</idno><idno type="eISSN">1098-1004</idno><imprint><biblScope unit="vol">33</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1123">1123</biblScope><biblScope unit="page" to="1132">1132</biblScope><biblScope unit="page-count">10</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-07">2012-07</date></imprint><idno type="ISSN">1059-7794</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1059-7794</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abcfs</term><term>Academia sinica</term><term>Accident insurance</term><term>Acute lymphoblastic leukaemia</term><term>Allele</term><term>Asian descent</term><term>Asian women</term><term>Association study</term><term>Bcac</term><term>Biocenter kuopio</term><term>Biomedical research centre</term><term>Biomedical sciences</term><term>Brca1</term><term>Brca1 mutations</term><term>Breakthrough breast cancer</term><term>Breakthrough breast cancer research centre</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer association consortium</term><term>Breast cancer cases</term><term>Breast cancer family registry</term><term>Breast cancer patients</term><term>Breast cancer risk</term><term>Breast cancer susceptibility loci</term><term>Bsuch study</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer council victoria</term><term>Cancer epidemiology</term><term>Cancer foundation</term><term>Cancer genetics</term><term>Cancer institute</term><term>Cancer prevention institute</term><term>Cancer research</term><term>Cancer research centre</term><term>Cancer studies</term><term>Cecile study</term><term>Cell cycle control</term><term>Centre</term><term>Clin</term><term>Clin cancer</term><term>Clinical genetics</term><term>Clinical medicine</term><term>Clinical pharmacology</term><term>College london</term><term>Common variants</term><term>Consortium</term><term>Coriell institute</term><term>Coronary artery disease</term><term>Cyclin</term><term>Deutsche krebshilfe</term><term>Deutsches krebsforschungszentrum</term><term>Dkfz</term><term>Ductal</term><term>Dutch cancer society</term><term>Eastern finland</term><term>Epidemiol</term><term>Epidemiology</term><term>Erlangen</term><term>Estrogen</term><term>Estrogen breast cancer</term><term>Estrogen receptor</term><term>European descent</term><term>European women</term><term>Evangelische kliniken bonn ggmbh</term><term>Familial breast cancer risk</term><term>Family history</term><term>Federal ministry</term><term>Finland</term><term>Fondazione irccs istituto nazionale tumori</term><term>Forest plots</term><term>Foundation trust</term><term>Gene expression</term><term>General population</term><term>Genet</term><term>Genetic variants</term><term>Genetics</term><term>German cancer research center</term><term>Gwas</term><term>Heidelberg</term><term>Helmholtz society</term><term>Helsinki</term><term>Helsinki university</term><term>Herlev university hospital</term><term>Heterogeneity</term><term>Heterozygous</term><term>Hiltrud brauch</term><term>Histology</term><term>Histology ductal</term><term>Histopathological subtype</term><term>Homozygous effect</term><term>Horizontal lines</term><term>Hormone receptor status</term><term>Human cancer genetics programme</term><term>Human genetics</term><term>Human mutation</term><term>Inst</term><term>Internal medicine</term><term>Johanniter krankenhaus</term><term>Kuopio</term><term>Kuopio university hospital</term><term>Laboratory medicine</term><term>Leiden university</term><term>Lobular</term><term>Locus</term><term>Mammographic density</term><term>Many others</term><term>Mayo clinic</term><term>Medical research</term><term>Medical research council</term><term>Melbourne</term><term>Minor allele frequencies</term><term>Molecular epidemiology group</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>National cancer institute</term><term>National health</term><term>Natl</term><term>Natl cancer inst</term><term>Nhmrc</term><term>Obstetrics</term><term>Occupational medicine</term><term>Odds ratio</term><term>Odds ratios</term><term>Ofbcr</term><term>Oncogenic driver</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Other tumors</term><term>Oulu</term><term>Oulu university hospital</term><term>Ovarian cancer</term><term>Pancreatic cancer</term><term>Polymorphism</term><term>Postgraduate school</term><term>Receptor</term><term>Repair genes</term><term>Research centre</term><term>Sample sizes</term><term>Samuel lunenfeld research institute</term><term>Sigrid juselius foundation</term><term>Sinai hospital</term><term>Single nucleotide polymorphism</term><term>Snp</term><term>Study abcfs</term><term>Study participants</term><term>Subgroup analyses</term><term>Susceptibility</term><term>Tumor characteristics</term><term>Tumor subtype</term><term>Tumor subtypes</term><term>Turnbull</term><term>Ucibcs</term><term>University breast center</term><term>University hospital</term><term>University hospital erlangen</term><term>University tubingen</term><term>Unselected breast cancer patients</term><term>Variant</term><term>Victorian breast cancer research consortium group leader</term><term>Western australia</term><term>Wiley periodicals</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Abcfs</term><term>Academia sinica</term><term>Accident insurance</term><term>Acute lymphoblastic leukaemia</term><term>Allele</term><term>Asian descent</term><term>Asian women</term><term>Association study</term><term>Bcac</term><term>Biocenter kuopio</term><term>Biomedical research centre</term><term>Biomedical sciences</term><term>Brca1</term><term>Brca1 mutations</term><term>Breakthrough breast cancer</term><term>Breakthrough breast cancer research centre</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer association consortium</term><term>Breast cancer cases</term><term>Breast cancer family registry</term><term>Breast cancer patients</term><term>Breast cancer risk</term><term>Breast cancer susceptibility loci</term><term>Bsuch study</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer council victoria</term><term>Cancer epidemiology</term><term>Cancer foundation</term><term>Cancer genetics</term><term>Cancer institute</term><term>Cancer prevention institute</term><term>Cancer research</term><term>Cancer research centre</term><term>Cancer studies</term><term>Cecile study</term><term>Cell cycle control</term><term>Centre</term><term>Clin</term><term>Clin cancer</term><term>Clinical genetics</term><term>Clinical medicine</term><term>Clinical pharmacology</term><term>College london</term><term>Common variants</term><term>Consortium</term><term>Coriell institute</term><term>Coronary artery disease</term><term>Cyclin</term><term>Deutsche krebshilfe</term><term>Deutsches krebsforschungszentrum</term><term>Dkfz</term><term>Ductal</term><term>Dutch cancer society</term><term>Eastern finland</term><term>Epidemiol</term><term>Epidemiology</term><term>Erlangen</term><term>Estrogen</term><term>Estrogen breast cancer</term><term>Estrogen receptor</term><term>European descent</term><term>European women</term><term>Evangelische kliniken bonn ggmbh</term><term>Familial breast cancer risk</term><term>Family history</term><term>Federal ministry</term><term>Finland</term><term>Fondazione irccs istituto nazionale tumori</term><term>Forest plots</term><term>Foundation trust</term><term>Gene expression</term><term>General population</term><term>Genet</term><term>Genetic variants</term><term>Genetics</term><term>German cancer research center</term><term>Gwas</term><term>Heidelberg</term><term>Helmholtz society</term><term>Helsinki</term><term>Helsinki university</term><term>Herlev university hospital</term><term>Heterogeneity</term><term>Heterozygous</term><term>Hiltrud brauch</term><term>Histology</term><term>Histology ductal</term><term>Histopathological subtype</term><term>Homozygous effect</term><term>Horizontal lines</term><term>Hormone receptor status</term><term>Human cancer genetics programme</term><term>Human genetics</term><term>Human mutation</term><term>Inst</term><term>Internal medicine</term><term>Johanniter krankenhaus</term><term>Kuopio</term><term>Kuopio university hospital</term><term>Laboratory medicine</term><term>Leiden university</term><term>Lobular</term><term>Locus</term><term>Mammographic density</term><term>Many others</term><term>Mayo clinic</term><term>Medical research</term><term>Medical research council</term><term>Melbourne</term><term>Minor allele frequencies</term><term>Molecular epidemiology group</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>National cancer institute</term><term>National health</term><term>Natl</term><term>Natl cancer inst</term><term>Nhmrc</term><term>Obstetrics</term><term>Occupational medicine</term><term>Odds ratio</term><term>Odds ratios</term><term>Ofbcr</term><term>Oncogenic driver</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Other tumors</term><term>Oulu</term><term>Oulu university hospital</term><term>Ovarian cancer</term><term>Pancreatic cancer</term><term>Polymorphism</term><term>Postgraduate school</term><term>Receptor</term><term>Repair genes</term><term>Research centre</term><term>Sample sizes</term><term>Samuel lunenfeld research institute</term><term>Sigrid juselius foundation</term><term>Sinai hospital</term><term>Single nucleotide polymorphism</term><term>Snp</term><term>Study abcfs</term><term>Study participants</term><term>Subgroup analyses</term><term>Susceptibility</term><term>Tumor characteristics</term><term>Tumor subtype</term><term>Tumor subtypes</term><term>Turnbull</term><term>Ucibcs</term><term>University breast center</term><term>University hospital</term><term>University hospital erlangen</term><term>University tubingen</term><term>Unselected breast cancer patients</term><term>Variant</term><term>Victorian breast cancer research consortium group leader</term><term>Western australia</term><term>Wiley periodicals</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Finlande</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cancer</term><term>Consortium</term><term>épidémiologie</term><term>Génétique</term><term>Histologie</term><term>Recherche médicale</term><term>Médecine du travail</term><term>Oulu</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A recent two‐stage genome‐wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, and rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (P ≤ 3 × 10−9) and weak evidence was observed for rs2380205 (P = 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per‐allele odds ratio 1.21, P = 4 × 10−39). The association for rs614367 was specific to estrogen receptor (ER)‐positive disease and strongest for ER plus progesterone receptor (PR)‐positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype. Hum Mutat 33:1123–1132, 2012. © 2012 Wiley Periodicals, Inc.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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