Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism
Identifieur interne : 003048 ( Main/Merge ); précédent : 003047; suivant : 003049Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism
Auteurs : M. Riehle [Allemagne] ; J. Bereiter-HahnSource :
- Arzneimittel-Forschung [ 0004-4172 ] ; 1994.
Descripteurs français
- Pascal (Inist)
English descriptors
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Abstract
The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected
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Pascal:94-0638675Le document en format XML
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