OcrV1, PascalFrancis, Checkpoint, bibRecord, 000A54

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Identifieur interne : 000A54 ( PascalFrancis/Checkpoint ); précédent : 000A53; suivant : 000A55

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Auteurs : M. Riehle [Allemagne] ; J. Bereiter-Hahn

Source :

Arzneimittel-Forschung [ 0004-4172 ] ; 1994.

RBID : Pascal:94-0638675

Descripteurs français

Pascal (Inist)
- Ouabaïne, Digitoxine, Cardiotonique, Coeur, Appareil circulatoire, Consommation oxygène, Métabolisme, Embryon, Contractilité, Myocyte, Culture cellulaire, Poulet, In vitro, Glycoside, Animal.

English descriptors

KwdEn :
- Animal, Cardiotonic agent, Cell culture, Chicken, Circulatory system, Contractility, Embryo, Glycoside, Heart, In vitro, Metabolism, Myocyte, Oxygen consumption.

Abstract

The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected

Affiliations:

Allemagne

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Pascal:94-0638675

Le document en format XML

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<s2>Frankfurt/Main</s2>
<s3>DEU</s3>
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<wicri:noRegion>Frankfurt/Main</wicri:noRegion>
<wicri:noRegion>cinematic cell res. group</wicri:noRegion>
<wicri:noRegion>Frankfurt/Main</wicri:noRegion>
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<author><name sortKey="Bereiter Hahn, J" sort="Bereiter Hahn, J" uniqKey="Bereiter Hahn J" first="J." last="Bereiter-Hahn">J. Bereiter-Hahn</name>
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<front><div type="abstract" xml:lang="en">The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected</div>
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Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri