OcrV1, PascalFrancis, Curation, bibRecord, 000905

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Identifieur interne : 000905 ( PascalFrancis/Curation ); précédent : 000904; suivant : 000906

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Auteurs : M. Riehle [Allemagne] ; J. Bereiter-Hahn

Source :

Arzneimittel-Forschung [ 0004-4172 ] ; 1994.

RBID : Pascal:94-0638675

Descripteurs français

Pascal (Inist)
- Ouabaïne, Digitoxine, Cardiotonique, Coeur, Appareil circulatoire, Consommation oxygène, Métabolisme, Embryon, Contractilité, Myocyte, Culture cellulaire, Poulet, In vitro, Glycoside, Animal.

English descriptors

KwdEn :
- Animal, Cardiotonic agent, Cell culture, Chicken, Circulatory system, Contractility, Embryo, Glycoside, Heart, In vitro, Metabolism, Myocyte, Oxygen consumption.

Abstract

The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected

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A08	`01`	`1`	`ENG`	`@1 Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism`
A11	`01`	`1`		`@1 RIEHLE (M.)`
A11	`02`	`1`		`@1 BEREITER-HAHN (J.)`
A14	`01`			`@1 Johann Wolfgan Goethe univ., cinematic cell res. group @2 Frankfurt/Main @3 DEU`
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C01	`01`		`ENG`	`@0 The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected`
C02	`01`	`X`		`@0 002B02F01`
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C03	`02`	`X`	`FRE`	`@0 Digitoxine @2 NK @2 FR @5 04`
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C03	`04`	`X`	`FRE`	`@0 Coeur @5 10`
C03	`04`	`X`	`ENG`	`@0 Heart @5 10`
C03	`04`	`X`	`SPA`	`@0 Corazón @5 10`
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C03	`06`	`X`	`SPA`	`@0 Consumo oxígeno @5 13`
C03	`07`	`X`	`FRE`	`@0 Métabolisme @5 16`
C03	`07`	`X`	`ENG`	`@0 Metabolism @5 16`
C03	`07`	`X`	`SPA`	`@0 Metabolismo @5 16`
C03	`08`	`X`	`FRE`	`@0 Embryon @5 17`
C03	`08`	`X`	`ENG`	`@0 Embryo @5 17`
C03	`08`	`X`	`SPA`	`@0 Embrión @5 17`
C03	`09`	`X`	`FRE`	`@0 Contractilité @5 18`
C03	`09`	`X`	`ENG`	`@0 Contractility @5 18`
C03	`09`	`X`	`SPA`	`@0 Contractilidad @5 18`
C03	`10`	`X`	`FRE`	`@0 Myocyte @5 19`
C03	`10`	`X`	`ENG`	`@0 Myocyte @5 19`
C03	`10`	`X`	`SPA`	`@0 Miocito @5 19`
C03	`11`	`X`	`FRE`	`@0 Culture cellulaire @5 20`
C03	`11`	`X`	`ENG`	`@0 Cell culture @5 20`
C03	`11`	`X`	`SPA`	`@0 Cultivo celular @5 20`
C03	`12`	`X`	`FRE`	`@0 Poulet @5 21`
C03	`12`	`X`	`ENG`	`@0 Chicken @5 21`
C03	`12`	`X`	`SPA`	`@0 Pollo @5 21`
C03	`13`	`X`	`FRE`	`@0 In vitro @5 22`
C03	`13`	`X`	`ENG`	`@0 In vitro @5 22`
C03	`13`	`X`	`SPA`	`@0 In vitro @5 22`
C03	`14`	`X`	`FRE`	`@0 Glycoside @5 27`
C03	`14`	`X`	`ENG`	`@0 Glycoside @5 27`
C03	`14`	`X`	`SPA`	`@0 Glicósido @5 27`
C03	`15`	`X`	`FRE`	`@0 Animal @5 78`
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N21				`@1 307`

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Pascal:94-0638675

Le document en format XML

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<author><name sortKey="Bereiter Hahn, J" sort="Bereiter Hahn, J" uniqKey="Bereiter Hahn J" first="J." last="Bereiter-Hahn">J. Bereiter-Hahn</name>
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<front><div type="abstract" xml:lang="en">The effects of 0.1 nmol/l ouabain (CAS 630-60-4) and digitoxin (CAS 71-63-6) on oxygen consumption rate (OCR) and the contractility of cultured chick embryo cardiomyocytes were investigated using a perfusion system which allowed microscopic observation during the experiment. Contractility was assessed by a novel image analysis procedure. During substrate free perfusion the OCR was increased on application of 0.1 nmol/l ouabain or digitoxin for 60 min, whilst contractility was not affected</div>
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Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism

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Descripteurs français

English descriptors

Abstract

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