Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound
Identifieur interne : 006567 ( Main/Curation ); précédent : 006566; suivant : 006568Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound
Auteurs : Oliver Stachs [Allemagne] ; Hanka Schneider [Allemagne] ; Joachim Stave [Allemagne] ; Rudolf Guthoff [Allemagne]Source :
- Journal of refractive surgery : (1995) [ 1081-597X ] ; 2005.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie.
English descriptors
- KwdEn :
Abstract
PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.
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Pascal:05-0148130Le document en format XML
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<front><div type="abstract" xml:lang="en">PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.</div>
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