Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?
Identifieur interne : 006566 ( Main/Curation ); précédent : 006565; suivant : 006567Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?
Auteurs : David J. Hernandez [États-Unis] ; Jonathan I. Epstein [États-Unis] ; Bruce J. Trock [États-Unis] ; Toyonori Tsuzuki [États-Unis] ; H. Ballentine Carter [États-Unis] ; Patrick C. Walsh [États-Unis]Source :
- The Journal of urology [ 0022-5347 ] ; 2005.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgien, Décision.
English descriptors
- KwdEn :
- Adult, Aged, Anatomic pathology, Clinical Competence, Decision, Decision making, Extension, General Surgery (statistics & numerical data), Humans, Male, Middle Aged, Neoplasm Invasiveness, Nephrology, Prostate, Prostate (blood supply), Prostate (innervation), Prostatectomy, Prostatic Neoplasms (pathology), Prostatic Neoplasms (surgery), Radical, Retrospective Studies, Support, Surgeon, Surgical margin, Technique, Treatment, Tumor, Urology.
- MESH :
- blood supply : Prostate.
- innervation : Prostate.
- pathology : Prostatic Neoplasms.
- statistics & numerical data : General Surgery.
- surgery : Prostatic Neoplasms.
- Adult, Aged, Clinical Competence, Humans, Male, Middle Aged, Neoplasm Invasiveness, Prostatectomy, Retrospective Studies.
Abstract
Purpose: We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons. Materials and Methods: A total of 204 men with EPE in the region of the NVB underwent surgery by 2 experienced surgeons. The frequency of PSMs in the area of the NVB as well as the nerve sparing status of each lobe of the prostate were determined through a retrospective investigation of the pathology database as well as the physician's database. The recovery of sexual function was determined and compared to controls. Results: The age, clinical stage, biopsy Gleason sum and serum prostate specific antigen of the patients operated on by surgeons 1 and 2 were similar. Surgeon 1 widely excised at least 1 neurovascular bundle in 16% of the patients and surgeon 2 in 63%. The overall frequency of PSMs at the NVB was 5.9% for surgeon 1 and 5.8% for surgeon 2. Of the evaluable patients followed for 12 months or longer 83.5% of those operated on by surgeon 1 were potent compared to 63.8% of those operated on by surgeon 2. Conclusions: Visual and tactile assessment during open surgery by an experienced surgeon provides valuable information on when and where it is safe to preserve the neurovascular bundle in patients with EPE in the region of the NVB. Surgical approaches in which tactile sensation is muted or absent, laparoscopic and robotic, need to undergo a similar evaluation to determine whether magnification of the operative field is sufficient to overcome the lack of haptic feedback and ability to palpate the tissue.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000F06
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :000602
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000B00
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :006910
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001998
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001998
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001686
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000679
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000679
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000679
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :006509
Links to Exploration step
Pascal:05-0079063Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J." last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I." last="Epstein">Jonathan I. Epstein</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J." last="Trock">Bruce J. Trock</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H. Ballentine" last="Carter">H. Ballentine Carter</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C." last="Walsh">Patrick C. Walsh</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">05-0079063</idno>
<date when="2005">2005</date>
<idno type="stanalyst">PASCAL 05-0079063 INIST</idno>
<idno type="RBID">Pascal:05-0079063</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000F06</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000602</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000B00</idno>
<idno type="wicri:doubleKey">0022-5347:2005:Hernandez D:radical:retropubic:prostatectomy</idno>
<idno type="wicri:Area/Main/Merge">006910</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:15643199</idno>
<idno type="wicri:Area/PubMed/Corpus">001998</idno>
<idno type="wicri:Area/PubMed/Curation">001998</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001686</idno>
<idno type="wicri:Area/Ncbi/Merge">000679</idno>
<idno type="wicri:Area/Ncbi/Curation">000679</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000679</idno>
<idno type="wicri:doubleKey">0022-5347:2005:Hernandez D:radical:retropubic:prostatectomy</idno>
<idno type="wicri:Area/Main/Merge">006509</idno>
<idno type="wicri:Area/Main/Curation">006566</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J." last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I." last="Epstein">Jonathan I. Epstein</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J." last="Trock">Bruce J. Trock</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H. Ballentine" last="Carter">H. Ballentine Carter</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C." last="Walsh">Patrick C. Walsh</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The Journal of urology</title>
<title level="j" type="abbreviated">J. urol.</title>
<idno type="ISSN">0022-5347</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The Journal of urology</title>
<title level="j" type="abbreviated">J. urol.</title>
<idno type="ISSN">0022-5347</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Anatomic pathology</term>
<term>Clinical Competence</term>
<term>Decision</term>
<term>Decision making</term>
<term>Extension</term>
<term>General Surgery (statistics & numerical data)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Nephrology</term>
<term>Prostate</term>
<term>Prostate (blood supply)</term>
<term>Prostate (innervation)</term>
<term>Prostatectomy</term>
<term>Prostatic Neoplasms (pathology)</term>
<term>Prostatic Neoplasms (surgery)</term>
<term>Radical</term>
<term>Retrospective Studies</term>
<term>Support</term>
<term>Surgeon</term>
<term>Surgical margin</term>
<term>Technique</term>
<term>Treatment</term>
<term>Tumor</term>
<term>Urology</term>
</keywords>
<keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="innervation" xml:lang="en"><term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>General Surgery</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Clinical Competence</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Prostatectomy</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Radical</term>
<term>Prostatectomie</term>
<term>Chirurgien</term>
<term>Extension</term>
<term>Prostate</term>
<term>Tumeur</term>
<term>Anatomopathologie</term>
<term>Décision</term>
<term>Prise décision</term>
<term>Support</term>
<term>Technique</term>
<term>Urologie</term>
<term>Traitement</term>
<term>Paquet neurovasculaire</term>
<term>Marge chirurgicale</term>
<term>Néphrologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgien</term>
<term>Décision</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Purpose: We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons. Materials and Methods: A total of 204 men with EPE in the region of the NVB underwent surgery by 2 experienced surgeons. The frequency of PSMs in the area of the NVB as well as the nerve sparing status of each lobe of the prostate were determined through a retrospective investigation of the pathology database as well as the physician's database. The recovery of sexual function was determined and compared to controls. Results: The age, clinical stage, biopsy Gleason sum and serum prostate specific antigen of the patients operated on by surgeons 1 and 2 were similar. Surgeon 1 widely excised at least 1 neurovascular bundle in 16% of the patients and surgeon 2 in 63%. The overall frequency of PSMs at the NVB was 5.9% for surgeon 1 and 5.8% for surgeon 2. Of the evaluable patients followed for 12 months or longer 83.5% of those operated on by surgeon 1 were potent compared to 63.8% of those operated on by surgeon 2. Conclusions: Visual and tactile assessment during open surgery by an experienced surgeon provides valuable information on when and where it is safe to preserve the neurovascular bundle in patients with EPE in the region of the NVB. Surgical approaches in which tactile sensation is muted or absent, laparoscopic and robotic, need to undergo a similar evaluation to determine whether magnification of the operative field is sufficient to overcome the lack of haptic feedback and ability to palpate the tissue.</div>
</front>
</TEI>
<double idat="0022-5347:2005:Hernandez D:radical:retropubic:prostatectomy"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J." last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I." last="Epstein">Jonathan I. Epstein</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J." last="Trock">Bruce J. Trock</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H. Ballentine" last="Carter">H. Ballentine Carter</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C." last="Walsh">Patrick C. Walsh</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">05-0079063</idno>
<date when="2005">2005</date>
<idno type="stanalyst">PASCAL 05-0079063 INIST</idno>
<idno type="RBID">Pascal:05-0079063</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000F06</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000602</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000B00</idno>
<idno type="wicri:doubleKey">0022-5347:2005:Hernandez D:radical:retropubic:prostatectomy</idno>
<idno type="wicri:Area/Main/Merge">006910</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J." last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I." last="Epstein">Jonathan I. Epstein</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J." last="Trock">Bruce J. Trock</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H. Ballentine" last="Carter">H. Ballentine Carter</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C." last="Walsh">Patrick C. Walsh</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The Journal of urology</title>
<title level="j" type="abbreviated">J. urol.</title>
<idno type="ISSN">0022-5347</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The Journal of urology</title>
<title level="j" type="abbreviated">J. urol.</title>
<idno type="ISSN">0022-5347</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anatomic pathology</term>
<term>Decision</term>
<term>Decision making</term>
<term>Extension</term>
<term>Nephrology</term>
<term>Prostate</term>
<term>Prostatectomy</term>
<term>Radical</term>
<term>Support</term>
<term>Surgeon</term>
<term>Surgical margin</term>
<term>Technique</term>
<term>Treatment</term>
<term>Tumor</term>
<term>Urology</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Radical</term>
<term>Prostatectomie</term>
<term>Chirurgien</term>
<term>Extension</term>
<term>Prostate</term>
<term>Tumeur</term>
<term>Anatomopathologie</term>
<term>Décision</term>
<term>Prise décision</term>
<term>Support</term>
<term>Technique</term>
<term>Urologie</term>
<term>Traitement</term>
<term>Paquet neurovasculaire</term>
<term>Marge chirurgicale</term>
<term>Néphrologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgien</term>
<term>Décision</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Purpose: We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons. Materials and Methods: A total of 204 men with EPE in the region of the NVB underwent surgery by 2 experienced surgeons. The frequency of PSMs in the area of the NVB as well as the nerve sparing status of each lobe of the prostate were determined through a retrospective investigation of the pathology database as well as the physician's database. The recovery of sexual function was determined and compared to controls. Results: The age, clinical stage, biopsy Gleason sum and serum prostate specific antigen of the patients operated on by surgeons 1 and 2 were similar. Surgeon 1 widely excised at least 1 neurovascular bundle in 16% of the patients and surgeon 2 in 63%. The overall frequency of PSMs at the NVB was 5.9% for surgeon 1 and 5.8% for surgeon 2. Of the evaluable patients followed for 12 months or longer 83.5% of those operated on by surgeon 1 were potent compared to 63.8% of those operated on by surgeon 2. Conclusions: Visual and tactile assessment during open surgery by an experienced surgeon provides valuable information on when and where it is safe to preserve the neurovascular bundle in patients with EPE in the region of the NVB. Surgical approaches in which tactile sensation is muted or absent, laparoscopic and robotic, need to undergo a similar evaluation to determine whether magnification of the operative field is sufficient to overcome the lack of haptic feedback and ability to palpate the tissue.</div>
</front>
</TEI>
</INIST>
<PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J" last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><nlm:affiliation>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I" last="Epstein">Jonathan I. Epstein</name>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J" last="Trock">Bruce J. Trock</name>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H Ballentine" last="Carter">H Ballentine Carter</name>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C" last="Walsh">Patrick C. Walsh</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2005">2005</date>
<idno type="RBID">pubmed:15643199</idno>
<idno type="pmid">15643199</idno>
<idno type="doi">10.1097/01.ju.0000151135.80249.c9</idno>
<idno type="wicri:Area/PubMed/Corpus">001998</idno>
<idno type="wicri:Area/PubMed/Curation">001998</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001686</idno>
<idno type="wicri:Area/Ncbi/Merge">000679</idno>
<idno type="wicri:Area/Ncbi/Curation">000679</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000679</idno>
<idno type="wicri:doubleKey">0022-5347:2005:Hernandez D:radical:retropubic:prostatectomy</idno>
<idno type="wicri:Area/Main/Merge">006509</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?</title>
<author><name sortKey="Hernandez, David J" sort="Hernandez, David J" uniqKey="Hernandez D" first="David J" last="Hernandez">David J. Hernandez</name>
<affiliation wicri:level="2"><nlm:affiliation>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Epstein, Jonathan I" sort="Epstein, Jonathan I" uniqKey="Epstein J" first="Jonathan I" last="Epstein">Jonathan I. Epstein</name>
</author>
<author><name sortKey="Trock, Bruce J" sort="Trock, Bruce J" uniqKey="Trock B" first="Bruce J" last="Trock">Bruce J. Trock</name>
</author>
<author><name sortKey="Tsuzuki, Toyonori" sort="Tsuzuki, Toyonori" uniqKey="Tsuzuki T" first="Toyonori" last="Tsuzuki">Toyonori Tsuzuki</name>
</author>
<author><name sortKey="Carter, H Ballentine" sort="Carter, H Ballentine" uniqKey="Carter H" first="H Ballentine" last="Carter">H Ballentine Carter</name>
</author>
<author><name sortKey="Walsh, Patrick C" sort="Walsh, Patrick C" uniqKey="Walsh P" first="Patrick C" last="Walsh">Patrick C. Walsh</name>
</author>
</analytic>
<series><title level="j">The Journal of urology</title>
<idno type="ISSN">0022-5347</idno>
<imprint><date when="2005" type="published">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Clinical Competence</term>
<term>General Surgery (statistics & numerical data)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Prostate (blood supply)</term>
<term>Prostate (innervation)</term>
<term>Prostatectomy</term>
<term>Prostatic Neoplasms (pathology)</term>
<term>Prostatic Neoplasms (surgery)</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="innervation" xml:lang="en"><term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>General Surgery</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Clinical Competence</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Prostatectomy</term>
<term>Retrospective Studies</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons.</div>
</front>
</TEI>
</PubMed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006566 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 006566 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Curation |type= RBID |clé= Pascal:05-0079063 |texte= Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle? }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |