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Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Identifieur interne : 000E98 ( PascalFrancis/Corpus ); précédent : 000E97; suivant : 000E99

Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Auteurs : Oliver Stachs ; Hanka Schneider ; Joachim Stave ; Rudolf Guthoff

Source :

RBID : Pascal:05-0148130

Descripteurs français

English descriptors

Abstract

PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 1081-597X
A02 01      @0 JRSUFZ
A03   1    @0 J. refract. surg. : (1995)
A05       @2 21
A06       @2 1
A08 01  1  ENG  @1 Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound
A11 01  1    @1 STACHS (Oliver)
A11 02  1    @1 SCHNEIDER (Hanka)
A11 03  1    @1 STAVE (Joachim)
A11 04  1    @1 GUTHOFF (Rudolf)
A14 01      @1 Eye Clinic of the U niversity of Rostock @2 Rostock @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut.
A20       @1 37-45
A21       @1 2005
A23 01      @0 ENG
A43 01      @1 INIST @2 21122 @5 354000129355820040
A44       @0 0000 @1 © 2005 INIST-CNRS. All rights reserved.
A45       @0 35 ref.
A47 01  1    @0 05-0148130
A60       @1 P
A61       @0 A
A64 01  1    @0 Journal of refractive surgery : (1995)
A66 01      @0 USA
C01 01    ENG  @0 PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.
C02 01  X    @0 002B25B
C03 01  X  FRE  @0 Lentille intraoculaire @5 02
C03 01  X  ENG  @0 Intraocular lens @5 02
C03 01  X  SPA  @0 Lente intraocular @5 02
C03 02  X  FRE  @0 In vitro @5 03
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C03 03  X  FRE  @0 In vivo @5 05
C03 03  X  ENG  @0 In vivo @5 05
C03 03  X  SPA  @0 In vivo @5 05
C03 04  X  FRE  @0 Echographie tridimensionnelle @5 06
C03 04  X  ENG  @0 Three-dimensional ultrasound @5 06
C03 04  X  SPA  @0 Ecografía tridimensional @5 06
C03 05  X  FRE  @0 Haute fréquence @5 08
C03 05  X  ENG  @0 High frequency @5 08
C03 05  X  SPA  @0 Alta frecuencia @5 08
C03 06  X  FRE  @0 Chirurgie @5 09
C03 06  X  ENG  @0 Surgery @5 09
C03 06  X  SPA  @0 Cirugía @5 09
C03 07  X  FRE  @0 Ophtalmologie @5 11
C03 07  X  ENG  @0 Ophthalmology @5 11
C03 07  X  SPA  @0 Oftalmología @5 11
N21       @1 101
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 05-0148130 INIST
ET : Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound
AU : STACHS (Oliver); SCHNEIDER (Hanka); STAVE (Joachim); GUTHOFF (Rudolf)
AF : Eye Clinic of the U niversity of Rostock/Rostock/Allemagne (1 aut., 2 aut., 3 aut., 4 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of refractive surgery : (1995); ISSN 1081-597X; Coden JRSUFZ; Etats-Unis; Da. 2005; Vol. 21; No. 1; Pp. 37-45; Bibl. 35 ref.
LA : Anglais
EA : PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.
CC : 002B25B
FD : Lentille intraoculaire; In vitro; In vivo; Echographie tridimensionnelle; Haute fréquence; Chirurgie; Ophtalmologie
ED : Intraocular lens; In vitro; In vivo; Three-dimensional ultrasound; High frequency; Surgery; Ophthalmology
SD : Lente intraocular; In vitro; In vivo; Ecografía tridimensional; Alta frecuencia; Cirugía; Oftalmología
LO : INIST-21122.354000129355820040
ID : 05-0148130

Links to Exploration step

Pascal:05-0148130

Le document en format XML

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<div type="abstract" xml:lang="en">PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.</div>
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<ET>Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound</ET>
<AU>STACHS (Oliver); SCHNEIDER (Hanka); STAVE (Joachim); GUTHOFF (Rudolf)</AU>
<AF>Eye Clinic of the U niversity of Rostock/Rostock/Allemagne (1 aut., 2 aut., 3 aut., 4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
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<EA>PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.</EA>
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<ED>Intraocular lens; In vitro; In vivo; Three-dimensional ultrasound; High frequency; Surgery; Ophthalmology</ED>
<SD>Lente intraocular; In vitro; In vivo; Ecografía tridimensional; Alta frecuencia; Cirugía; Oftalmología</SD>
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<ID>05-0148130</ID>
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   |texte=   Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound
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