Infrared skin damage thresholds from 1940-nm continuous-wave laser exposures.
Identifieur interne : 000460 ( PubMed/Curation ); précédent : 000459; suivant : 000461Infrared skin damage thresholds from 1940-nm continuous-wave laser exposures.
Auteurs : Jeffrey W. Oliver [États-Unis] ; David J. Stolarski ; Gary D. Noojin ; Harvey M. Hodnett ; Corey A. Harbert ; Kurt J. Schuster ; Michael F. Foltz ; Semih S. Kumru ; Clarence P. Cain ; C J Finkeldei ; Gavin D. Buffington ; Isaac D. Noojin ; Robert J. ThomasSource :
- Journal of biomedical optics [ 1560-2281 ]
Descripteurs français
- KwdFr :
- Animaux, Brûlures (physiopathologie), Brûlures (étiologie), Dose de radiation, Exposition environnementale (effets indésirables), Lésions radio-induites (physiopathologie), Lésions radio-induites (étiologie), Modèles biologiques, Peau (effets des radiations), Peau (physiopathologie), Peau (traumatismes), Porc miniature, Rayons infrarouges (effets indésirables), Relation dose-effet des radiations, Seuil différentiel (effets des radiations), Simulation numérique, Suidae, Température cutanée (effets des radiations).
- MESH :
- effets des radiations : Peau, Seuil différentiel, Température cutanée.
- effets indésirables : Exposition environnementale, Rayons infrarouges.
- physiopathologie : Brûlures, Lésions radio-induites, Peau.
- traumatismes : Peau.
- étiologie : Brûlures, Lésions radio-induites.
- Animaux, Dose de radiation, Modèles biologiques, Porc miniature, Relation dose-effet des radiations, Simulation numérique, Suidae.
English descriptors
- KwdEn :
- Animals, Burns (etiology), Burns (physiopathology), Computer Simulation, Differential Threshold (radiation effects), Dose-Response Relationship, Radiation, Environmental Exposure (adverse effects), Infrared Rays (adverse effects), Models, Biological, Radiation Dosage, Radiation Injuries (etiology), Radiation Injuries (physiopathology), Skin (injuries), Skin (physiopathology), Skin (radiation effects), Skin Temperature (radiation effects), Swine, Swine, Miniature.
- MESH :
- adverse effects : Environmental Exposure, Infrared Rays.
- etiology : Burns, Radiation Injuries.
- injuries : Skin.
- physiopathology : Burns, Radiation Injuries, Skin.
- radiation effects : Differential Threshold, Skin, Skin Temperature.
- Animals, Computer Simulation, Dose-Response Relationship, Radiation, Models, Biological, Radiation Dosage, Swine, Swine, Miniature.
Abstract
A series of experiments are conducted in vivo using Yucatan mini-pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1940-nm continuous-wave thulium fiber laser irradiation. Experiments employ exposure durations from 10 ms to 10 s and beam diameters of approximately 4.8 to 18 mm. Thermal imagery data provide a time-dependent surface temperature response from the laser. A damage endpoint of minimally visible effect is employed to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of optical-thermal interaction. Results are compared with current exposure limits for laser safety. It is concluded that exposure limits should be based on data representative of large-beam exposures, where effects of radial diffusion are minimized for longer-duration damage thresholds.
DOI: 10.1117/1.3523622
PubMed: 21198172
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pubmed:21198172Le document en format XML
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<term>Suidae</term>
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<term>Dose de radiation</term>
<term>Modèles biologiques</term>
<term>Porc miniature</term>
<term>Relation dose-effet des radiations</term>
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<term>Suidae</term>
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<front><div type="abstract" xml:lang="en">A series of experiments are conducted in vivo using Yucatan mini-pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1940-nm continuous-wave thulium fiber laser irradiation. Experiments employ exposure durations from 10 ms to 10 s and beam diameters of approximately 4.8 to 18 mm. Thermal imagery data provide a time-dependent surface temperature response from the laser. A damage endpoint of minimally visible effect is employed to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of optical-thermal interaction. Results are compared with current exposure limits for laser safety. It is concluded that exposure limits should be based on data representative of large-beam exposures, where effects of radial diffusion are minimized for longer-duration damage thresholds.</div>
</front>
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<Abstract><AbstractText>A series of experiments are conducted in vivo using Yucatan mini-pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1940-nm continuous-wave thulium fiber laser irradiation. Experiments employ exposure durations from 10 ms to 10 s and beam diameters of approximately 4.8 to 18 mm. Thermal imagery data provide a time-dependent surface temperature response from the laser. A damage endpoint of minimally visible effect is employed to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of optical-thermal interaction. Results are compared with current exposure limits for laser safety. It is concluded that exposure limits should be based on data representative of large-beam exposures, where effects of radial diffusion are minimized for longer-duration damage thresholds.</AbstractText>
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